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Int J Cardiol：动态应力计算机断层扫描心肌灌注检测心肌缺血性能分析！

2018-02-10 xing.T MedSci原创

DCTMP心肌缺血性能
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由此可见，DCTMP在诊断心肌缺血方面具有较高的诊断准确性，在联合应用冠状动脉CTA的情况下，DCTMP可能在血管节段层面上的诊断准确性显著增加。

与SPECT和MRI相比，随着时间和空间分辨率的提高以及辐射剂量减少的发展，心肌计算机断层扫描灌注已经成为评价血液动力学心肌缺血的潜在方法。近日，心血管领域权威杂志International Journal of Cardiology上发表了一篇荟萃分析文章，该文章系统地分析了动态CT心肌灌注（DCTMP）诊断心肌缺血（MI）的性能，并与临床已知的参考方法[MR/SPECT/PET灌注和分流量储备（FFR）]作为参考标准。

研究人员检索了PubMed、Embase和web of science 数据库，以评估符合纳入标准的DCTMP诊断MI的准确性，并将检验类型作为随机效应协变量的二变量混合效应回归模型的精确二项式再现来合成可用的数据。

研究人员查找了13个符合条件的研究，包含482名患者。在血管节段层面，心肌血流量（MBF）合并的灵敏度和特异性分别为0.83（95％可信区间为0.80-0.86）和0.90（95％可信区间为0.88-0.91）；在动脉层面，分别为0.85（95％可信区间为0.80-0.88）和0.81（95％可信区间为0.78-0.84）；在患者层面，分别为0.93（95％可信区间为0.82-0.98）和0.82（95％可信区间为0.70-0.91）。MBF的sROC曲线下面积分别在血管节段层面为0.944，血管层面为0.911，患者层面为0.949。

由此可见，DCTMP在诊断心肌缺血方面具有较高的诊断准确性，在联合应用冠状动脉CTA的情况下，DCTMP可能在血管节段层面上的诊断准确性显著增加。

原始出处：

Minjie Lu,et al. Dynamic stress computed tomography myocardial perfusion for detecting myocardial ischemia: A systematic review and meta-analysis.International Journal of Cardiology.2018. https://doi.org/10.1016/j.ijcard.2018.01.095

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    2019-01-15 仁者大医

    #Cardiol#

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    2018-12-15 lishiwen

    #能分析#

    0

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    2018-10-24 12498e5fm19(暂无昵称)

    #心肌灌注#

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    2018-10-17 bioon14

    #计算机#

    0

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    2018-05-10 guihongzh

    #缺血性#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1781866, encodeId=f56f1e8186613, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Tue Jan 15 08:16:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1809968, encodeId=f0051809968ef, content=<a href='/topic/show?id=2b9d8426121' target=_blank style='color:#2F92EE;'>#能分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84261, encryptionId=2b9d8426121, topicName=能分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sat Dec 15 21:16:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642508, encodeId=4720164250880, content=<a href='/topic/show?id=8210512940e' target=_blank style='color:#2F92EE;'>#心肌灌注#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51294, encryptionId=8210512940e, topicName=心肌灌注)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=754b22951372, createdName=12498e5fm19(暂无昵称), createdTime=Wed Oct 24 07:16:00 CST 2018, time=2018-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1716388, encodeId=52631e163881e, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Wed Oct 17 08:16:00 CST 2018, time=2018-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893017, encodeId=a162189301ed2, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu May 10 07:16:00 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591070, encodeId=ec0315910e002, content=<a href='/topic/show?id=ed574924e8c' target=_blank style='color:#2F92EE;'>#应力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49247, encryptionId=ed574924e8c, topicName=应力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Mon Feb 12 07:16:00 CST 2018, time=2018-02-12, status=1, ipAttribution=)]
    2018-02-12 jiangjun073

    #应力#

    0