Arthritis Care & Research:止痛剂+运动治疗膝盖OA疗效可

2016-03-20 Mechront 译 MedSci原创

近期发表在Arthritis Care & Research的研究称,对膝盖骨关节炎(OA)和严重膝盖疼痛患者,使用止痛剂+运动疗法可显著改善疼痛和活动受限。阿姆斯特丹康复研究中心的Joyce A. C. van Tunen和同事对49名膝盖OA和严重膝盖疼的患者进行了研究,探究止痛剂+运动疗法对该类患者的结局影响,评估该疗法的可行性。先予以患者止痛剂,6周后,再添加长达12周的运动疗法。

近期发表在Arthritis Care & Research的研究称,对膝盖骨关节炎(OA)和严重膝盖疼痛患者,使用止痛剂+运动疗法可显著改善疼痛和活动受限。

阿姆斯特丹康复研究中心的Joyce A. C. van Tunen和同事对49名膝盖OA和严重膝盖疼的患者进行了研究,探究止痛剂+运动疗法对该类患者的结局影响,评估该疗法的可行性。先予以患者止痛剂,6周后,再添加长达12周的运动疗法。在纳入研究时、试验6周和18周后分别评估患者的膝盖疼痛和活动受限情况。

通过ITT分析,研究人员发现,在止痛剂使用6周后和干预结局后,患者的膝盖疼痛和活动受限情况现在改善。从纳入研究开始,到止痛剂+运动疗法干预结局,患者的膝盖疼痛和活动受限情况分别平均改善30%和17%(P值均<0.001)。整体上,有78%的患者能够按照试验标准进行运动,这些患者中,在6周止痛药之后的运动疗法将可以改善10%的膝盖活动受限(P = 0.004)。

作者写道:“虽然该项研究得到了不错的结局,但是在未来还需要进行随机对照试验以验证该结果。”

原始出处:


Joyce A. C. van Tunen,Marike van der Leeden,et al.Optimization of Analgesics for Greater Exercise Therapy Participation Among Patients With Knee Osteoarthritis and Severe Pain: A Feasibility Study.Arthritis Care & Research.Volume 68, Issue 3, pages 332–340, March 2016

Analgesics plus exercise therapy feasible for knee OA.MedicalXpress.March 11, 2016


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    2017-01-20 cooco
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    2016-03-22 zhaojie88
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    2016-03-22 yangshch

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