只需几滴血:日团队开发诊断阿尔茨海默症新方法

2017-09-05 中新网 尹海华

9月5日电 据日媒报道,日本京都府立医科大学神经内科学教授德田隆彦等的团队近日在海外专业杂志网络版上发表研究成果称,开发了使用从手腕采集的血液可诊断是否患有阿尔茨海默症的方法。

9月5日电 据日媒报道,日本京都府立医科大学神经内科学教授德田隆彦等的团队近日在海外专业杂志网络版上发表研究成果称,开发了使用从手腕采集的血液可诊断是否患有阿尔茨海默症的方法。

德田表示:“新方法对于身体的负担少,很简便,可正确且迅速地辨别。”

据该团队称,名为“tau蛋白”的蛋白质中,容易积聚在脑内这一类型的tau蛋白增加就易患阿尔茨海默症,因此在诊断中测定血内异常tau蛋白的含量。迄今也存在从脑脊髓液中检测的方法,但需要用针刺入背部采集。

此外,从脑部转移至血液中的tau蛋白极其微量,因此测定存在难度。该团队则利用了与tau蛋白结合的抗体为标记这一点,采用特殊分析仪器,使得能以过去千倍的敏感度检测出血液内的tau蛋白。

据称,使用新方法分析了60至89岁男女20人的血液后,确认了存在患者的异常tau蛋白量较高的倾向,获知可用于诊断。

该团队表示,未来设想用于记忆测试等前实施的患者迅速筛查等中,为投入实际运用将携手相关企业展开研究。

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