J Gerontol A Biol:中年人的感官损伤和认知功能

2017-05-29 AlexYang MedSci原创

听力、视觉和嗅觉的损伤与老年人的认知功能损伤有关,但是与中年人认知功能的关系却知道很少。最近,研究人员利用Beaver Dam Offspring研究对参与者进行了感官和认知功能的基线调查(2005-2008)。并利用Trail Making测试A(TMTA)和B(TMTB)以及Grooved Peg Board测试进行了认知功能的测量。另外,研究人员利用纯音听觉测试、Pelli-Robson信息

听力、视觉和嗅觉的损伤与老年人的认知功能损伤有关,但是与中年人认知功能的关系却知道很少。最近,研究人员利用Beaver Dam Offspring研究对参与者进行了感官和认知功能的基线调查(2005-2008)。并利用Trail Making测试A(TMTA)和B(TMTB)以及Grooved Peg Board测试进行了认知功能的测量。另外,研究人员利用纯音听觉测试、Pelli-Robson信息表和圣地亚哥气味鉴定测试分别测量了听力、对比灵敏度和嗅觉情况。

研究总共包括了年龄在21-84岁的2836名参与者,并进行了听力、视觉、嗅觉和认知功能的基线检查。研究发现,19%的参与者具有一种感官损伤,3%的参与者具有多种感官损伤,并且嗅觉损伤与较差的TMTA、TMTB和Grooved Peg Board表现独立相关(在所有模型和感官损伤中p<0.05)。另外,具有一种感官损伤的参与者要比对应的没有感官损伤的参与者平均花费时间要长2到10秒来完成测试。在模型中以及助听器使用调整的模型中结果是相似的。最后,研究人员指出,听力、视觉和嗅觉损伤与认知功能较差的表现有关,并且与其他感官损伤和认知相关因素没有联系。中年人的感官损伤与认知功能的轻微缺陷有关,这也许象征着早期的脑损伤。

原始出处:

Schubert CR, Cruickshanks KJ, Fischer ME et al. Sensory Impairments and Cognitive Function in Middle-Aged Adults. J Gerontol A Biol. 23 May 2017.

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    2017-09-03 sunylz
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