Nat Commun:钻石可有助于癌症的早期检测

2015-10-13 sunshine 译 MedSci原创

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玛丽莲梦露曾说过,“钻石是女人最好的朋友,”但是,据发表于Nature Communications的一项新的研究揭示了珍贵的宝石如何成为男性及女性有价值的伴侣:它们可有助于检测早期癌症。该研究详细的介绍了纳米钻石如何增强早期癌组织的磁共振成像。

本研究中,研究人员将纳米钻石称为超极化过程,这个过程中,钻石内部的原子排列产生一个可被MRI扫描捕捉到的信号。

本研究第一作者Ewa Rej,来自悉尼大学物理学院,解释道,通过将钻石超极化成为可靶向定位癌细胞的分子,研究人员可在体内追踪分子的运动轨迹。

“将这些靶向定位某特定肿瘤细胞的化学物质粘附至某些类型的受体上,是一项很先进的技术,” Prof. Reilly说道,“我们现在所做的就是要让这些分子在进行MRI过程中发光,让我们不通过手术就能直观地看到癌组织。”

Rej相信,本研究的发现为癌症的早期诊断和治疗提供了一种有前景的策略:

“这是物理学研究解决现实问题的一个很好的例子,本研究为癌细胞发展成为致命状态之前的癌前组织的成像及靶向治疗开辟了新的道路。”

研究人员指出,虽然钻石是昂贵的宝石,但是相比之下,本研究中合成的版本却是十分廉价的,并可广泛使用。

Prof. Reilly 说道,“这是个好消息,因为我们不希望围绕一个在地球以外的地方挖掘出来的的技术建立某些医疗技术。”

现在,研究人员正计划测试纳米钻石在动物模型中对癌细胞的检测作用。

原始出处:


Ewa Rej,Torsten Gaebel,et,al.Hyperpolarized nanodiamond with long spin-relaxation times.Nat Commun.2015


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    2016-05-06 liuli5079
  2. [GetPortalCommentsPageByObjectIdResponse(id=2086829, encodeId=643020868290d, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Fri May 06 00:11:00 CST 2016, time=2016-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880837, encodeId=619a188083e88, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Nov 18 04:11:00 CST 2015, time=2015-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39284, encodeId=6be439284fb, content=谢谢分享~, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:17:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39285, encodeId=d56a39285a9, content=为了积分我也是拼了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:17:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39283, encodeId=1b9c392835e, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:16:00 CST 2015, time=2015-10-18, status=1, ipAttribution=)]
    2015-11-18 liye789132251
  3. [GetPortalCommentsPageByObjectIdResponse(id=2086829, encodeId=643020868290d, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Fri May 06 00:11:00 CST 2016, time=2016-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880837, encodeId=619a188083e88, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Nov 18 04:11:00 CST 2015, time=2015-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39284, encodeId=6be439284fb, content=谢谢分享~, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:17:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39285, encodeId=d56a39285a9, content=为了积分我也是拼了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:17:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=39283, encodeId=1b9c392835e, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Oct 18 22:16:00 CST 2015, time=2015-10-18, status=1, ipAttribution=)]
    2015-10-18 sunlong28

    谢谢分享~

    0

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    2015-10-18 sunlong28

    为了积分我也是拼了~

    0

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    2015-10-18 sunlong28

    赞一个

    0