Eur Heart J:MIDA死亡风险评分:退行性二尖瓣返流早晚期死亡预后模型的建立和外部验证

2017-08-19 xiangting MedSci原创

MIDA评分可能是DMR管理的创新工具,能够将患者定位在连续的短长期死亡风险范围内。

在退行性二尖瓣返流(DMR)中,缺乏预测死亡的死亡率评分导致对患者风险的误判和不恰当决策。

二尖瓣返流国际数据库(MIDA)登记包括3666名患者(年龄66±14岁; 70%男性;随访7.8±5.0年),在三级医疗中心通过超声心动图诊断为单纯性孤立DMR(欧洲/北/南美洲)。MIDA评分来自MIDA-Flail登记(2472例DMR患者和连枷状瓣叶推定队列),通过加权所有指南提供的预后指标,并在MIDA-BNP登记中进行外部验证(1194例DMR患者和连枷状瓣叶/脱垂验证队列)。MIDA得分范围从0到12,取决于累积的风险因素。在预测诊断后的总死亡率,MIDA评分在推定队列(c ?= 0.78)和验证队列(c?= 0.81)中有很好的一致性。在整个MIDA队列(n ?= 3666例)中,评分0,7-8和11-12的1年死亡率分别为治疗情况下0.4,17和48%,手术后1,7,14% (P<0.001)。评分0,7-8,11-12的5年生存率分别为治疗情况下98±1,57±4和21±10%,手术后99±1,82±2和57±9%P<0.001)。在包括所有指南提供的预后标志物和EuroScoreII模型中,MIDA评分提供了增加的预后信息(P≤0.002)。

MIDA评分可能是DMR管理的创新工具,能够将患者定位在连续的短长期死亡风险范围内。这种创新的预后指标可能为将来的临床试验提供一个具体框架,旨在比较针对同类风险患者的DMR治疗新技术。

原始出处:

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1951956, encodeId=0a9f195195614, content=<a href='/topic/show?id=ebc011e60fb' target=_blank style='color:#2F92EE;'>#MIDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11760, encryptionId=ebc011e60fb, topicName=MIDA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Fri Oct 27 16:23:00 CST 2017, time=2017-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255663, encodeId=81fb1255663f3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356476, encodeId=52f913564e6d8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418745, encodeId=c1e51418e452f, content=<a href='/topic/show?id=e5be23919cf' target=_blank style='color:#2F92EE;'>#二尖瓣返流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23919, encryptionId=e5be23919cf, topicName=二尖瓣返流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad623409629, createdName=kksonne, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463165, encodeId=adde1463165ec, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562669, encodeId=2450156266922, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
    2017-10-27 mjldent
  2. [GetPortalCommentsPageByObjectIdResponse(id=1951956, encodeId=0a9f195195614, content=<a href='/topic/show?id=ebc011e60fb' target=_blank style='color:#2F92EE;'>#MIDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11760, encryptionId=ebc011e60fb, topicName=MIDA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Fri Oct 27 16:23:00 CST 2017, time=2017-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255663, encodeId=81fb1255663f3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356476, encodeId=52f913564e6d8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418745, encodeId=c1e51418e452f, content=<a href='/topic/show?id=e5be23919cf' target=_blank style='color:#2F92EE;'>#二尖瓣返流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23919, encryptionId=e5be23919cf, topicName=二尖瓣返流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad623409629, createdName=kksonne, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463165, encodeId=adde1463165ec, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562669, encodeId=2450156266922, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1951956, encodeId=0a9f195195614, content=<a href='/topic/show?id=ebc011e60fb' target=_blank style='color:#2F92EE;'>#MIDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11760, encryptionId=ebc011e60fb, topicName=MIDA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Fri Oct 27 16:23:00 CST 2017, time=2017-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255663, encodeId=81fb1255663f3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356476, encodeId=52f913564e6d8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418745, encodeId=c1e51418e452f, content=<a href='/topic/show?id=e5be23919cf' target=_blank style='color:#2F92EE;'>#二尖瓣返流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23919, encryptionId=e5be23919cf, topicName=二尖瓣返流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad623409629, createdName=kksonne, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463165, encodeId=adde1463165ec, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562669, encodeId=2450156266922, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
    2017-08-21 zhaojie88
  4. [GetPortalCommentsPageByObjectIdResponse(id=1951956, encodeId=0a9f195195614, content=<a href='/topic/show?id=ebc011e60fb' target=_blank style='color:#2F92EE;'>#MIDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11760, encryptionId=ebc011e60fb, topicName=MIDA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Fri Oct 27 16:23:00 CST 2017, time=2017-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255663, encodeId=81fb1255663f3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356476, encodeId=52f913564e6d8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418745, encodeId=c1e51418e452f, content=<a href='/topic/show?id=e5be23919cf' target=_blank style='color:#2F92EE;'>#二尖瓣返流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23919, encryptionId=e5be23919cf, topicName=二尖瓣返流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad623409629, createdName=kksonne, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463165, encodeId=adde1463165ec, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562669, encodeId=2450156266922, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1951956, encodeId=0a9f195195614, content=<a href='/topic/show?id=ebc011e60fb' target=_blank style='color:#2F92EE;'>#MIDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11760, encryptionId=ebc011e60fb, topicName=MIDA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Fri Oct 27 16:23:00 CST 2017, time=2017-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255663, encodeId=81fb1255663f3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356476, encodeId=52f913564e6d8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418745, encodeId=c1e51418e452f, content=<a href='/topic/show?id=e5be23919cf' target=_blank style='color:#2F92EE;'>#二尖瓣返流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23919, encryptionId=e5be23919cf, topicName=二尖瓣返流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad623409629, createdName=kksonne, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463165, encodeId=adde1463165ec, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562669, encodeId=2450156266922, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
    2017-08-21 wwzzly
  6. [GetPortalCommentsPageByObjectIdResponse(id=1951956, encodeId=0a9f195195614, content=<a href='/topic/show?id=ebc011e60fb' target=_blank style='color:#2F92EE;'>#MIDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11760, encryptionId=ebc011e60fb, topicName=MIDA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Fri Oct 27 16:23:00 CST 2017, time=2017-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255663, encodeId=81fb1255663f3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356476, encodeId=52f913564e6d8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418745, encodeId=c1e51418e452f, content=<a href='/topic/show?id=e5be23919cf' target=_blank style='color:#2F92EE;'>#二尖瓣返流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23919, encryptionId=e5be23919cf, topicName=二尖瓣返流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad623409629, createdName=kksonne, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463165, encodeId=adde1463165ec, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562669, encodeId=2450156266922, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Aug 21 07:23:00 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
    2017-08-21 slcumt

相关资讯

JACC Cardiovasc Interv:新型ARTO系统治疗功能性二尖瓣返流安全有效

新型ARTO系统可改善二尖瓣返流(FMR),因此,本研究评估了新型ARTO系统对心力衰竭患者和功能性二尖瓣返流的治疗效果。 MAVERIC试验是一项前瞻性,非随机化的研究。关键入选标准为患者均为收缩性心衰、NYHA心功能II~IV级、功能性二尖瓣返流等级大于2级、左心室射血分数小于等于40%、左室舒张末期内径在50 mm~75 mm之间。主要安全性终点是30天主要不良事件,有效性终点为二尖瓣返流

ACC 2014:哪些严重二尖瓣返流患者适宜早期手术治疗?

2014年美国心脏病学会年会(ACC 2014)公布的一项研究表明,在年龄≥50岁的严重二尖瓣返流(MR)但无症状的患者中,与保守治疗相比,早期手术与其心血管死亡和心脏事件长期减少显著相关。研究论文3月30日在线发表于《美国心脏病学杂志》(J Am Coll Cardiol)。 研究共纳入610例严重MR但无症状的序贯患者,前瞻性评估保留的左心室功能。接受早期手术和常规治疗的病例数分别为235例