Stroke:急性脑桥梗死患者吞咽困难的预测因素!

2017-04-12 xing.T MedSci原创

由此可见,吞咽困难在孤立性脑桥梗死患者中经常发生。吞咽困难的临床和影像学预测可能有助于提供最佳的筛选,以防止并发症和改善长期预后。

对于脑桥卒中神经源性吞咽障碍的发生频率和临床特征知之甚少。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,在这项研究中,研究人员试图通过一组孤立的脑桥梗死患者找出吞咽困难的预测因素。

研究人员纳入在2008年至2014年期间入住研究人员所在医疗机构的所有通过磁共振弥散加权成像证实的急性(症状发作后的48小时)脑桥缺血性卒中患者。精确的梗死定位根据确定的血管领域进行分层。吞咽困难是该研究的主要终点,并且通过语言病理学家根据明确的标准来进行评估。

该研究招募了59例患者,其中14例为吞咽困难患者,45例患者无吞咽困难。卒中严重程度(国立卫生研究院健康卒中量表值)的中位数(四分位距)在吞咽困难组患者中较高,相比于无吞咽困难的患者(8.5 [6-12] vs. 2 [1-5];P<0.001)。梗死灶位于脑桥上部(78.6% vs. 33.3%;P=0.004)和血管区域前外侧(78.6% vs. 31.1%;P=0.002)在发生吞咽困难的患者中更加常见。在多变量模型中,年龄、梗死体积和国立卫生研究院卒中量表值是吞咽困难的独立预测因子。

由此可见,吞咽困难在孤立性脑桥梗死患者中经常发生。吞咽困难的临床和影像学预测可能有助于提供最佳的筛选,以防止并发症和改善长期预后。

原始出处:

Sriramya Lapa,et al. Predictors of Dysphagia in Acute Pontine Infarction.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.116.015045

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    2017-07-03 amy0560
  2. [GetPortalCommentsPageByObjectIdResponse(id=1695646, encodeId=7fae1695646f2, content=<a href='/topic/show?id=d7298488274' target=_blank style='color:#2F92EE;'>#脑桥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84882, encryptionId=d7298488274, topicName=脑桥)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937429851027, createdName=amy0560, createdTime=Mon Jul 03 08:35:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187494, encodeId=e20318e4949a, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xjZ9qh3bhXrJtUlmycKGfQKPuADVZQsdNAQj5IrHHlzbGsDwScictBgogYRk8KhicpgEKwTEfOHgqw/0, createdBy=bc931611963, createdName=jin321, createdTime=Sat Apr 15 00:06:36 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264241, encodeId=a852126424167, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri Apr 14 01:35:00 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1318601, encodeId=2b46131860146, content=<a href='/topic/show?id=25eb391692f' target=_blank style='color:#2F92EE;'>#吞咽困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39169, encryptionId=25eb391692f, topicName=吞咽困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5eee468, createdName=zxl729, createdTime=Fri Apr 14 01:35:00 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186933, encodeId=bd14186933b4, content=很简单啊貌似, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Wed Apr 12 21:27:52 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186886, encodeId=75ee1868860d, content=很好的idea,说实话,国内好多中心都有条件做类似研究的,只是……, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Wed Apr 12 13:04:23 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186870, encodeId=3c5c1868e005, content=文章已经收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Apr 12 10:52:56 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-15 jin321

    有意义

    0

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    2017-04-12 dachengl

    很简单啊貌似

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1695646, encodeId=7fae1695646f2, content=<a href='/topic/show?id=d7298488274' target=_blank style='color:#2F92EE;'>#脑桥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84882, encryptionId=d7298488274, topicName=脑桥)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937429851027, createdName=amy0560, createdTime=Mon Jul 03 08:35:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187494, encodeId=e20318e4949a, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xjZ9qh3bhXrJtUlmycKGfQKPuADVZQsdNAQj5IrHHlzbGsDwScictBgogYRk8KhicpgEKwTEfOHgqw/0, createdBy=bc931611963, createdName=jin321, createdTime=Sat Apr 15 00:06:36 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264241, encodeId=a852126424167, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri Apr 14 01:35:00 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1318601, encodeId=2b46131860146, content=<a href='/topic/show?id=25eb391692f' target=_blank style='color:#2F92EE;'>#吞咽困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39169, encryptionId=25eb391692f, topicName=吞咽困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5eee468, createdName=zxl729, createdTime=Fri Apr 14 01:35:00 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186933, encodeId=bd14186933b4, content=很简单啊貌似, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Wed Apr 12 21:27:52 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186886, encodeId=75ee1868860d, content=很好的idea,说实话,国内好多中心都有条件做类似研究的,只是……, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Wed Apr 12 13:04:23 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186870, encodeId=3c5c1868e005, content=文章已经收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Apr 12 10:52:56 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-12 baihao215

    很好的idea,说实话,国内好多中心都有条件做类似研究的,只是……

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1695646, encodeId=7fae1695646f2, content=<a href='/topic/show?id=d7298488274' target=_blank style='color:#2F92EE;'>#脑桥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84882, encryptionId=d7298488274, topicName=脑桥)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937429851027, createdName=amy0560, createdTime=Mon Jul 03 08:35:00 CST 2017, time=2017-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187494, encodeId=e20318e4949a, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xjZ9qh3bhXrJtUlmycKGfQKPuADVZQsdNAQj5IrHHlzbGsDwScictBgogYRk8KhicpgEKwTEfOHgqw/0, createdBy=bc931611963, createdName=jin321, createdTime=Sat Apr 15 00:06:36 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264241, encodeId=a852126424167, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri Apr 14 01:35:00 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1318601, encodeId=2b46131860146, content=<a href='/topic/show?id=25eb391692f' target=_blank style='color:#2F92EE;'>#吞咽困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39169, encryptionId=25eb391692f, topicName=吞咽困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5eee468, createdName=zxl729, createdTime=Fri Apr 14 01:35:00 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186933, encodeId=bd14186933b4, content=很简单啊貌似, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Wed Apr 12 21:27:52 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186886, encodeId=75ee1868860d, content=很好的idea,说实话,国内好多中心都有条件做类似研究的,只是……, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Wed Apr 12 13:04:23 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186870, encodeId=3c5c1868e005, content=文章已经收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Apr 12 10:52:56 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-12 milkshark

    文章已经收藏

    0