JAMA:髋部骨折手术时用局部麻醉与较低的死亡风险没有关系

2014-06-26 佚名 EurekAlert!

据6月25日刊《美国医学会杂志》上的一则研究披露,在2004年至2011年间接受髋关节修复术的5万6000多名成年人中,与全身麻醉相比,使用局部麻醉与术后30天时死亡风险的下降没有关系,但与住院时间的适度缩短有关。 每年,美国会发生30多万起的髋骨骨折,它会导致功能性能力丧失和死亡。根据文章的背景资料,在做髋部骨折手术时使用局部麻醉可减少手术后并发症,而手术指南呼吁更广泛地用局部麻醉来进行髋部骨

据6月25日刊《美国医学会杂志》上的一则研究披露,在2004年至2011年间接受髋关节修复术的5万6000多名成年人中,与全身麻醉相比,使用局部麻醉与术后30天时死亡风险的下降没有关系,但与住院时间的适度缩短有关。

每年,美国会发生30多万起的髋骨骨折,它会导致功能性能力丧失和死亡。根据文章的背景资料,在做髋部骨折手术时使用局部麻醉可减少手术后并发症,而手术指南呼吁更广泛地用局部麻醉来进行髋部骨折手术。

费城宾夕法尼亚大学Perelman医学院的Mark D. Neuman, M.D., M.Sc.及其同事对局部麻醉(即脊髓或硬膜外麻醉)vs 全身麻醉对髋部骨折手术后30天死亡率及住院时间长短的关系进行了评估。该研究包括了年龄50岁或以上的病人,他们在2004年7月至2011年12月间在纽约州的普通急诊治疗医院中接受了髋部骨折手术。

在5万6729个病人中,有1万5904人(28%)接受了局部麻醉,有4万又825人(72%)则接受了全身麻醉。总体而言,有3032位病人(5.3%)在术后30天内死亡。研究人员没有观察到因为麻醉技术不同而在死亡率上有具有统计意义的差异。但他们确实发现,局部麻醉与住院时间缩短大约半天有关。

文章的作者写道:“我们的发现可能对临床实践及卫生政策具有意义。局部麻醉是在美国及其它国家中在少数髋部骨折手术中所用的主要麻醉方法,而有人曾经提出增加其应用来作为改善髋关节骨折治疗品质的一个策略。我们发现在更多应用局部麻醉与髋部骨折术后住院时间缩短之间有关联;然而,我们没有发现局部麻醉与死亡率之间的统计学显著差异有关。”

“这些结果不支持局部麻醉在这种情况下会有减少死亡的裨益。”

原始出处:

Use of regional anesthesia during hip fracture surgery not associated with lower risk of death.EurekAlert Jun 25 2014.

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    2014-06-28 chg122
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    2014-06-28 liuquan
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