Heart:D-二聚体和CRP可预测主动脉夹层院内死亡

2013-07-13 MedSci MedSci原创

  首都医科大学附属北京安贞医院的马长生和董建增等探讨了血浆D—二聚体和C反应蛋白(CRP)在预测急性主动脉夹层(AD)院内死亡所起的作用,结果发现,血浆D—二聚体≥5.67 μg/mL、CRP ≥11.21 mg/L和A型急性主动脉夹层是AD院内死亡的重要危险因素,且与其独立相关。论文6月28日在线发表于《心脏》(Heart)杂志。  该单中心前瞻性研究入选了114例急性AD患者,测定

  首都医科大学附属北京安贞医院的马长生和董建增等探讨了血浆D—二聚体和C反应蛋白(CRP)在预测急性主动脉夹层(AD)院内死亡所起的作用,结果发现,血浆D—二聚体≥5.67 μg/mL、CRP ≥11.21 mg/L和A型急性主动脉夹层是AD院内死亡的重要危险因素,且与其独立相关。论文6月28日在线发表于《心脏》(Heart)杂志。

  该单中心前瞻性研究入选了114例急性AD患者,测定患者入院D—二聚体和CRP的浓度,观察D—二聚体和CRP与院内死亡的相关性。

  结果显示,与生存者相比,那些死亡的患者血浆D—二聚体、CRP水平和主动脉直径有增加。另外,A型夹层患者的血浆D—二聚体浓度比B型夹层患者的高(P= 0.013)。血浆D—二聚体浓度与CRP水平和主动脉直径呈正相关关系,与AD分型和发病时间呈负相关。D—二聚体和CRP水平以及AD分型与院内死亡强相关。另外,D—二聚体≥5.67 μg/mL预测急性AD院内死亡的敏感性和特异性分别为90.3% 和75.9%,CRP ≥11.21 mg/L的敏感性和特异性分别为100% 和54.2%。

原始出处:

Wen D, Du X, Dong JZ, Zhou XL, Ma CS.Value of D-dimer and C reactive protein in predicting inhospital death in acute aortic dissection.Heart. 2013 Jul 8.

PDF文件下载:heartjnl-2013-304158.full.pdf

 

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    2013-09-17 hxj0117
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    2013-07-14 rebeccajiejie
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    2013-07-14 zhaojie88
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1950342, encodeId=fcb5195034205, content=<a href='/topic/show?id=bfc624041dc' target=_blank style='color:#2F92EE;'>#二聚体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24041, encryptionId=bfc624041dc, topicName=二聚体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac59108, createdName=hxj0117, createdTime=Tue Sep 17 06:23:00 CST 2013, time=2013-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1635224, encodeId=2798163522489, content=<a href='/topic/show?id=bb41983049e' target=_blank style='color:#2F92EE;'>#院内死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98304, encryptionId=bb41983049e, topicName=院内死亡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78f122436081, createdName=yuhaisheng_ibp_32061718, createdTime=Thu Nov 14 01:23:00 CST 2013, time=2013-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269569, encodeId=0e3a1269569be, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310835, encodeId=dea1131083561, content=<a href='/topic/show?id=b15c5628e9' target=_blank style='color:#2F92EE;'>#D-二聚体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5628, encryptionId=b15c5628e9, topicName=D-二聚体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355776, encodeId=7b151355e76af, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414958, encodeId=69cc14149587d, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519499, encodeId=b30715194996e, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562174, encodeId=184915621e438, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1950342, encodeId=fcb5195034205, content=<a href='/topic/show?id=bfc624041dc' target=_blank style='color:#2F92EE;'>#二聚体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24041, encryptionId=bfc624041dc, topicName=二聚体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac59108, createdName=hxj0117, createdTime=Tue Sep 17 06:23:00 CST 2013, time=2013-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1635224, encodeId=2798163522489, content=<a href='/topic/show?id=bb41983049e' target=_blank style='color:#2F92EE;'>#院内死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98304, encryptionId=bb41983049e, topicName=院内死亡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78f122436081, createdName=yuhaisheng_ibp_32061718, createdTime=Thu Nov 14 01:23:00 CST 2013, time=2013-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269569, encodeId=0e3a1269569be, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310835, encodeId=dea1131083561, content=<a href='/topic/show?id=b15c5628e9' target=_blank style='color:#2F92EE;'>#D-二聚体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5628, encryptionId=b15c5628e9, topicName=D-二聚体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355776, encodeId=7b151355e76af, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414958, encodeId=69cc14149587d, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519499, encodeId=b30715194996e, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562174, encodeId=184915621e438, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Jul 14 15:23:00 CST 2013, time=2013-07-14, status=1, ipAttribution=)]
    2013-07-14 slcumt

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