JACC:父母长寿可降低后代心血管风险

2016-08-18 Seven L 译 MedSci原创

美国心脏病学院杂志的一项新的研究显示,如果中年人的父母寿命超过69岁的时间越长,那么这名中年人心血管事件和死亡风险明显降的更低。也就是说,父母长寿和后代低心血管风险有关。来自克塞特大学医学院公共卫生和流行病学的教授David Melzer博士对186151名55-73岁参与者进行了研究,目的是研究父母长寿和后代早发心血管事件发病率之间的关联。随访8年,收集入院和死亡等相关信息。后代参与者平均年龄为

美国心脏病学院杂志的一项新的研究显示,如果中年人的父母寿命超过69岁的时间越长,那么这名中年人心血管事件和死亡风险明显降的更低。也就是说,父母长寿和后代低心血管风险有关。

来自克塞特大学医学院公共卫生和流行病学的教授David Melzer博士对186151名55-73岁参与者进行了研究,目的是研究父母长寿和后代早发心血管事件发病率之间的关联。随访8年,收集入院和死亡等相关信息。

后代参与者平均年龄为63岁,53%为女性。在基线时,更长的父母寿命与更高的后代教育、更高的收入、更多的运动、更低的吸烟率和更低的肥胖率有关。

根据调查结果,父母寿命超过69岁与后代全因死亡率和冠心病死亡率呈负相关;父母额外多活10年,后代全因死亡率下降16%-17%,冠心病死亡率下降20%-21%。

此外,父母长寿与后代多种心血管疾病发生率的下降有关(死亡 HR=0.82; 95% CI, 0.76-0.87;HF HR=0.86; 95% CI, 0.81-0.91;卒中 HR=0.88; 95% CI, 0.83-0.93;高血压 HR=0.88; 95% CI, 0.86-0.91;冠心病 HR=0.91; 95% CI, 0.88-0.94;贫血 HR=0.91; 95% CI, 0.86-0.96;高胆固醇血症 HR=0.93; 95% CI, 0.9-0.96;房颤 HR=0.94; 95% CI, 0.9-0.97)。

研究者称,众所周知避免吸烟等危险因素对于心脏健康是非常重要的,我们的研究表明,除了之前我们的普遍认识以外,父母的寿命也会对心脏健康产生影响。

研究人员指出了这项研究的一些局限性,包括缺乏代表性、后代年龄范围有限等。他们指出,还需要进一步的研究来确定父母寿命和后代心血管风险的联系。

原始出处:

Parental longevity linked to lower CV risk among offspring.Healio.August 17, 2016

Atkins JL, et al. Longer-Lived Parents and Cardiovascular Outcomes.J Am Coll Cardiol. 2016;doi:10.1016/j.jacc.2016.05.072.

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    2016-12-05 hbwxf
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    2016-09-25 1e10c84am36(暂无匿称)

    文章很好值得关注

    0

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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105372, encodeId=4d2c1053e2b1, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 08:31:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-09-06 李东泽

    很好,不错,以后会多学习

    0

  6. 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encodeId=074210542118, content=遗传基因挺重要,, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Sat Aug 27 10:09:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105407, encodeId=6d9a10540e5b, content=学习了,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sat Aug 27 09:20:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105372, encodeId=4d2c1053e2b1, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 08:31:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-31 1771ae4158m

    还得靠爸妈呀

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 08:08:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=112445, encodeId=c1b71124457c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Sep 06 16:16:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108060, encodeId=8b0c10806024, content=还得靠爸妈呀, beContent=null, 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105372, encodeId=4d2c1053e2b1, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 08:31:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-28 李东泽

    很好的文章。

    0

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105372, encodeId=4d2c1053e2b1, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 08:31:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-27 186****0580(小山羊)

    遗传基因挺重要,

    0

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105372, encodeId=4d2c1053e2b1, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 08:31:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-27 1771ae4158m

    学习了,好

    0

  10. 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    2016-08-27 ylzr123

    赞!文章有深度,值得收藏拜读。

    0

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