Crit Care:体外膜肺氧合治疗急性失代偿性心力衰竭效果如何?

2017-05-05 xing.T MedSci原创

在选取的105例接受体外膜肺氧合治疗急性失代偿性心力衰竭患者中,其1年生存率为42%,但在体外膜肺氧合前序贯器官衰竭评分小于11的患者中生存率更好。体外膜肺氧合对于急性失代偿性心力衰竭患者应给予考虑,但是接受治疗的时机是至关重要的。

用体外膜式氧合治疗急性失代偿性心力衰竭(即心源性休克并发慢性心肌病)患者的长期预后尚未被报道。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,该研究旨在描述其结局,并确定死亡相关因素。

该研究为前瞻性收集数据的回顾性分析,是在26个三级医院的ICU内完成,105例患者接受了体外膜式氧合治疗急性失代偿性心力衰竭。

从2007年3月至2015年1月期间,在研究人员所在机构共有105例患者接受体外膜式氧合治疗的急性失代偿性心力衰竭患者(其中67%有主动脉内球囊反搏泵为左心室减负)。其1年的生存率为42%,大多数幸存者直接或随后切换到中央双侧离心泵、心室辅助装置或整个人工心脏。大多数死亡发生在多器官衰竭早期。多变量分析(比值比95%可信区间[CI])发现体外膜肺氧合前序贯器官衰竭评分超过11(3.3 [1.3-8.3])、特发性心肌病(0.4[0.2-1])、体外膜肺氧合前心脏病持续时间大于2年(2.8[1.2-6.9])以及体外膜肺氧合前血乳酸水平大于4毫摩尔/升(2.6[1.03-6.4])仍是1年死亡率的独立预测因素。只有17%的体外膜肺氧合前顺序器官衰竭评估分数大于14分的患者可以存活,而52%的患者分数不到7分,60%的患者分数在7分以上但小于11分的患者存活了1年。

在选取的105例接受体外膜肺氧合治疗急性失代偿性心力衰竭患者中,其1年生存率为42%,但在体外膜肺氧合前序贯器官衰竭评分小于11的患者中生存率更好。体外膜肺氧合对于急性失代偿性心力衰竭患者应给予考虑,但是接受治疗的时机是至关重要的。

原始出处:

Dangers, Laurence,et al. Extracorporeal Membrane Oxygenation for Acute Decompensated Heart Failure.Critical Care.2017. http://journals.lww.com/ccmjournal/Abstract/publishahead/Extracorporeal_Membrane_Oxygenation_for_Acute.96601.aspx

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    2018-01-29 120e71dcm28暂无昵称

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    2017-06-24 海之蓝

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    2017-06-10 海之蓝

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    2017-05-06 tanxingdoctor

    学习了谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=283136, encodeId=826f283136f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b4b12216028, createdName=120e71dcm28暂无昵称, createdTime=Mon Jan 29 09:22:33 CST 2018, time=2018-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214850, encodeId=7c672148509a, content=xxxx, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, createdBy=eeaf2031798, createdName=海之蓝, createdTime=Sat Jun 24 16:15:04 CST 2017, time=2017-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209118, encodeId=dd12209118b0, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, createdBy=eeaf2031798, createdName=海之蓝, createdTime=Sat Jun 10 22:41:16 CST 2017, time=2017-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194477, encodeId=fc0b1944e73d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sat May 06 09:13:00 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194399, encodeId=8a7c194399d3, content=好文,值得点赞,更值得收藏!慢慢领会学习的。给点个赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat May 06 07:00:37 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194244, encodeId=c4ff19424468, content=心肌病预后都不太好, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhbPwBo0yCebU4qpdSwzpBA1WFXMEUicoTnJDickpj9Ve1cUdNjjTiaDXmpXL47LYh3DdYkPOA2kddyZ/0, createdBy=508c2054450, createdName=solarjin, createdTime=Fri May 05 19:10:59 CST 2017, time=2017-05-05, status=1, ipAttribution=)]
    2017-05-06 ylzr123

    好文,值得点赞,更值得收藏!慢慢领会学习的。给点个赞!

    0

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    2017-05-05 solarjin

    心肌病预后都不太好

    0