Lancet Planetary Health:农业和畜牧业中减少抗生素使用对耐药菌的影响

2017-11-07 zhangfan MedSci原创

限制食品生产和牲畜业中抗生素的使用可减少这些动物体内的抗生素耐药细菌,减少通过食物链导致的人体抗生素耐药

人类医学、兽医学和农业领域的抗生素应用导致全球范围内的抗生素耐药。近日研究人员开展系统综述和荟萃分析概述了减少食品生产和牲畜中抗生素使用的干预措施对动物和人类中存在抗药性细菌的影响。

研究人员收集了截止2017年1月27日相关研究资料,纳入标准是关于减少食物生产和动物抗生素使用的干预措施的原始研究报告,并比较了动物和人类干预组和对照组之间抗生素耐药菌的存在情况差异。研究的主要终点是抗生素耐药菌比例的风险差异。

总计181个研究纳入本次荟萃分析,其中179个研究考察了动物的抗生素耐药性,21个研究包含人类抗生素耐药性。在限制抗生素使用的干预措施中,依据不同的抗生素类别,样本类型,细菌,动物抗生素耐药性流行的绝对风险降低了10-15%。人类研究中,干预组与对照组相比,耐药性流行的绝对风险降低了24%。

限制食品生产和牲畜业中抗生素的使用可减少这些动物体内的抗生素耐药细菌,减少通过食物链导致的人体抗生素耐药。

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    2018-05-09 howi
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    2018-07-02 shizhenshan
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    2018-05-01 canlab
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