Diabetologia:研究表明环境毒素全氟化合物和糖尿病发病存在相关性

2014-01-03 佚名 医学界

全氟化合物是环境毒素,被发现存在于灭火泡沫和防水纺织中。在一项新研究中,Uppsala大学研究小组分析了血中高水平全氟化合物和糖尿病之间的联系。【原文下载】 该研究小组先前揭示高水平的环境毒素如PCB,农药,邻苯二甲酸盐和糖尿病之间有关联。在新的研究中,他们研究另一种类型环境毒素,即所谓的全氟化合物,其水平的升高是否与糖尿病有关。 全氟化合物被用于多种工业和消费

全氟化合物是环境毒素,被发现存在于灭火泡沫和防水纺织中。在一项新研究中,Uppsala大学研究小组分析了血中高水平全氟化合物和糖尿病之间的联系。【原文下载】

该研究小组先前揭示高水平的环境毒素如PCB,农药,邻苯二甲酸盐和糖尿病之间有关联。在新的研究中,他们研究另一种类型环境毒素,即所谓的全氟化合物,其水平的升高是否与糖尿病有关。

全氟化合物被用于多种工业和消费产品,包括消防泡沫,不粘炊具,以及油脂和防水材料等。在一组千余名70岁男性和女性参加的研究中,Uppsala大学研究人员测定血液七个不同全氟化合物的水平,并评价这些指标与糖尿病发病的相关性。

这七个全氟化合物在几乎所有的试验参与者体内都检测到,研究人员发现全氟化合物的高水平,特别是全氟化合物中的一种,全氟壬酸(PFNA),与糖尿病相关。此外,全氟辛酸(PFOA)也与糖尿病发病有关。Monica Lind副教授解释说:我们还看到,PFOA与胰腺胰岛素分泌受阻有关。

原文出处:

Lind L, Zethelius B, Salihovic S, van Bavel B, Lind PM.Circulating levels of perfluoroalkyl substances and prevalent diabetes in the elderly.Diabetologia. 2013 Dec 14. 【原文下载】

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    2016-02-28 kittydog

    为PFCs的毒力研究提供了参考,非常谢谢。

    0

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    2014-01-04 60.55.43.102

    太深奥了,可以做申报基金参考

    0

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