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Community Dent Oral Epidemiol：母亲产前暴露于汞合金 儿童无注意力缺陷风险

2018-09-15 邵金龙 编译 中国医学论坛报今日口腔

汞合金儿童无注意力缺陷
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挪威的一项大型前瞻性队列研究表明，母亲产前暴露于汞合金充填物的儿童并无注意力缺陷和多动症相关症状风险增加的迹象。本研究于2018年8月7日在线发表在《社区口腔流行病学》（Community Dent Oral Epidemiol）杂志。


挪威的一项大型前瞻性队列研究表明，母亲产前暴露于汞合金充填物的儿童并无注意力缺陷和多动症相关症状风险增加的迹象。本研究于2018年8月7日在线发表在《社区口腔流行病学》（Community Dent Oral Epidemiol）杂志。

注意力缺陷和多动症（ADHD）与多种因素有关，包括遗传因素和环境因素。因为银汞合金含有汞以及其可能对后代的神经发育产生负面后果的潜在风险，用于牙科治疗的银汞合金的安全性一直被讨论。该研究的目的是调查3~5岁儿童的ADHD相关症状与产前母亲银汞合金充填物产生的汞暴露之间的可能关联。研究中使用挪威母婴队列研究（MoBa）的数据，通过在妊娠第17周（Q1）和第30周（Q3）以及当孩子3岁（Q6）和5岁（Q7）时给受试妇女发送问卷收集数据。有关妊娠期间接触银汞合金的信息从Q3中获得，而有关ADHD症状的信息则来自Q6和Q7。实验中共获得了42163名3岁儿童和23392名5岁儿童的有效数据。采用逻辑回归模型对包括母亲的年龄、教育程度、体重指数、胎次、吸烟和妊娠期间的酒精消耗等因素来评估ADHD症状与产前接触应汞合金充填物之间的关联。

结果为，3岁和5岁儿童的ADHD相关的症状与银汞合金充填的牙齿数量、妊娠期间放置或移除的银汞合金充填物并无显著关联。

原始出处：

Lygre GB,et al.Prenatal exposure to dental amalgam and risk of symptoms of attention-deficit and hyperactivity disorder (ADHD).Community Dent Oral Epidemiol. 2018 Aug 7. doi: 10.1111/cdoe.12409. [Epub ahead of print]

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    2018-11-14 ms3153534357578991

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    2019-04-26 小几洁

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    2018-09-17 楚秀娟

    #合金#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2054055, encodeId=82632054055f9, content=<a href='/topic/show?id=5dd064322d7' target=_blank style='color:#2F92EE;'>#汞合金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64322, encryptionId=5dd064322d7, topicName=汞合金)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=606c2500035, createdName=ms3153534357578991, createdTime=Wed Nov 14 20:04:00 CST 2018, time=2018-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020475, encodeId=d85020204e575, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Apr 26 00:04:00 CST 2019, time=2019-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2087425, encodeId=168d208e425ad, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Sun May 12 20:04:00 CST 2019, time=2019-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465403, encodeId=dba41465403a1, content=<a href='/topic/show?id=662a388823e' target=_blank style='color:#2F92EE;'>#合金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38882, encryptionId=662a388823e, topicName=合金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=81df6719716, createdName=楚秀娟, createdTime=Mon Sep 17 07:04:00 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502539, encodeId=5a36150253994, content=<a href='/topic/show?id=ef4b2441971' target=_blank style='color:#2F92EE;'>#产前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24419, encryptionId=ef4b2441971, topicName=产前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b49a9545081, createdName=qilu_qi, createdTime=Mon Sep 17 07:04:00 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515703, encodeId=ce641515e03b1, content=<a href='/topic/show?id=cd636500e2e' target=_blank style='color:#2F92EE;'>#注意力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65007, encryptionId=cd636500e2e, topicName=注意力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=096e10855142, createdName=12498c24m72暂无昵称, createdTime=Mon Sep 17 07:04:00 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345112, encodeId=4fb334511258, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sat Sep 15 16:38:09 CST 2018, time=2018-09-15, status=1, ipAttribution=)]
    2018-09-17 qilu_qi

    #产前#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2054055, encodeId=82632054055f9, content=<a href='/topic/show?id=5dd064322d7' target=_blank style='color:#2F92EE;'>#汞合金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64322, encryptionId=5dd064322d7, topicName=汞合金)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=606c2500035, createdName=ms3153534357578991, createdTime=Wed Nov 14 20:04:00 CST 2018, time=2018-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020475, encodeId=d85020204e575, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Apr 26 00:04:00 CST 2019, time=2019-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2087425, encodeId=168d208e425ad, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Sun May 12 20:04:00 CST 2019, time=2019-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465403, encodeId=dba41465403a1, content=<a href='/topic/show?id=662a388823e' target=_blank style='color:#2F92EE;'>#合金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38882, encryptionId=662a388823e, topicName=合金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=81df6719716, createdName=楚秀娟, createdTime=Mon Sep 17 07:04:00 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502539, encodeId=5a36150253994, content=<a href='/topic/show?id=ef4b2441971' target=_blank style='color:#2F92EE;'>#产前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24419, encryptionId=ef4b2441971, topicName=产前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b49a9545081, createdName=qilu_qi, createdTime=Mon Sep 17 07:04:00 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515703, encodeId=ce641515e03b1, content=<a href='/topic/show?id=cd636500e2e' target=_blank style='color:#2F92EE;'>#注意力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65007, encryptionId=cd636500e2e, topicName=注意力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=096e10855142, createdName=12498c24m72暂无昵称, createdTime=Mon Sep 17 07:04:00 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345112, encodeId=4fb334511258, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sat Sep 15 16:38:09 CST 2018, time=2018-09-15, status=1, ipAttribution=)]
    2018-09-17 12498c24m72暂无昵称

    #注意力#

    0

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    2018-09-15 医者仁心5538

    学习了

    0

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