Alzheimers Dement:警惕!焦虑症可增加老年痴呆症的发病风险

2015-12-28 MedSci MedSci原创

据发表于Alzheimers Dementia的一项新的研究发现表明,焦虑可能会增加老年痴呆的发病风险。

据发表于Alzheimers Dementia的一项新的研究发现表明,焦虑可能会增加老年痴呆的发病风险。

“痴呆患者通常伴有精神疾病及精神紊乱,而精神疾病和精神紊乱是可以治疗的。焦虑症是老年人最常见的精神疾病。焦虑可影响机体的健康,如增加医疗费用,降低生活质量,还可能会增加残疾的发生风险。日后生活中,焦虑与认知功能的下降有关,而且通常与老年痴呆症共同存在,” Andrew J. Petkus博士及其同事写道,“然而,既往关于探究焦虑症是老年痴呆症的一个危险因素的研究却得出了不同的结果。”

为了确定焦虑是否可影响痴呆的发生风险以及是否有遗传因素参与了此过程,研究人员进行了此项研究。研究共纳入了1082对双胞胎,并无痴呆症患者。1984年开始此项研究,随访28年后进行评估。

结果发现基线时期的焦虑评分与随访期间研究对象出现痴呆症之间存在着明显的关联。对于基线时期焦虑评分较高的研究对象患老年痴呆症的风险较无焦虑症状的研究对象高48%。

双生子分析显示,异卵双胞胎之间焦虑症状和老年痴呆症的关联较同卵双胞胎之间更为密切。

“焦虑症可增加痴呆的发生风险这一发现具有重要的临床意义,”Petkus其同事写道, “根据主观报告和客观认知来评估老年人的认知功能时,重要的是评估机体的焦虑状况。卫生保健提供者往往会误诊患者老年时期的焦虑症;该研究表明,这些症状可能是机体日后老年痴呆症发生的一个特别重要的危险因素。此外,我们的研究结果表明,即使是亚临床焦虑也是痴呆发生的一个危险因素,表明,临床医生应关注老年人的焦虑症,而不仅仅是已确诊的焦虑症患者。”

原始出处:

Petkus AJ, et al.Anxiety may increase risk for dementia. Alzheimers Dement. 2015;doi:10.1016/j.jalz.2015.09.008. December 23, 2015.


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    2016-07-28 仁者大医
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    2016-02-03 Boyinsh
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