JAHA:导管消融术作为室上性心动过速一线治疗并未充分发挥作用

2022-06-08 MedSci原创 MedSci原创

在这项Logistic回归分析中,CA作为一线治疗的独立预测因素表明,导管消融对哪些患者最有利,在决策过程中存在偏差,这一医疗决策中的偏差导致导管消融术使用不足。

导管消融术(CA)是一种安全、经济有效的治疗技术,可被认为是有症状的室上性心动过速(SVT)的一线治疗策略。CA与改善患者生活质量、控制患者症状以及获得较高的满意度相关。从经济角度来看,对症状严重的患者进行CA治疗证明具有成本效益。但是当前数据表明从SVT诊断到CA手术的平均时间可能长达14年,提示CA可能存在延迟。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在评估SVT患者将CA作为一线治疗的相关预测因素。

该模型来自于一个三级中心的SVT或心室预兴奋CA患者组成的回顾性队列。在逐步Logistic回归分析中,研究人员将临床和人口特征作为自变量,非转诊的CA作为一线治疗的因变量。在350例患者的20个临床人口统计变量中,有10个纳入了初始logistic回归分析:包括年龄、女性、ECG上存在预兴奋、心悸、呼吸困难和胸部不适、消融术前服用抗心律失常药物的数量、伴随症状的数量、症状持续时间和因SVT而在急诊就诊。

经多变量调整分析,年龄(比值比[OR]为1.2;95%可信区间为1.01-1.32;P=0.04)、室上性心动过速时伴有胸部不适(OR为2.7;95%可信区间为1.6-4.7;P<0.001)和消融术前服用抗心律失常药物的数量(OR为1.8;95%可信区间为1.4-2.3;P<0.001)与将CA作为SVT一线治疗之间存在正相关性。

由此可见,在这项Logistic回归分析中,CA作为一线治疗的独立预测因素表明,导管消融对哪些患者最有利,在决策过程中存在偏差,这一医疗决策中的偏差导致导管消融术使用不足。

原始出处:

Lucas Hollanda Oliveira.et al.Underuse of Catheter Ablation as First‐Line Therapy for Supraventricular Tachycardia.JAHA.2022.https://www.ahajournals.org/doi/10.1161/JAHA.121.022648

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    2022-06-08 146de973m94暂无昵称

    学到了

    0

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    2022-06-08 zhaohui6731
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