颈动脉斑块需要他汀治疗吗?

2017-10-27 郭艺芳 郭艺芳心前沿

近年来颈动脉超声检查普遍开展,很多患者或健康查体者被发现有颈动脉斑块。存在颈动脉斑块者需要应用他汀治疗吗?这是临床上经常被患者问到的问题。这个问题无法一概而论,应结合患者的颈动脉狭窄程度、是否存在心血管病或心血管病危险因素以及低密度脂蛋白胆固醇(LDL-C)水平综合考虑。

近年来颈动脉超声检查普遍开展,很多患者或健康查体者被发现有颈动脉斑块。存在颈动脉斑块者需要应用他汀治疗吗?这是临床上经常被患者问到的问题。这个问题无法一概而论,应结合患者的颈动脉狭窄程度、是否存在心血管病或心血管病危险因素以及低密度脂蛋白胆固醇(LDL-C)水平综合考虑。可以按照以下方法做出初步决定:

若颈动脉斑块导致了颈动脉明显狭窄(狭窄≥50%),其处理原则与确诊冠心病或缺血性卒中相同(均属于动脉粥样硬化性心血管疾病),应该立即接受他汀治疗,将LDL-C控制在1.8mmol/L以下。并且多数患者还应考虑接受阿司匹林抗血小板治疗。

若颈动脉斑块未导致明显狭窄(狭窄程度<50%),则需要评估患者是否存在心血管病或其他心血管病危险因素。可有以下几种情况:

1.已确诊冠心病或缺血性卒中,无论颈动脉有无明显狭窄均应立即接受他汀治疗,将LDL-C控制在1.8mmol/L以下;

2.无冠心病和缺血性卒中,但患有糖尿病并伴高血压,也应服用他汀将LDL-C控制在1.8mmol/L以下;

3.年龄≥40岁的糖尿病患者,且LDL-C>2.6 mmol/L,需要接受他汀治疗;

4.慢性肾病(III期或IV期)且LDL-C>2.6 mmol/L,需要接受他汀治疗;

5.存在高血压或其他危险因素、且LDL-C>3.4 mmol/L,建议应用他汀治疗将LDL-C降至<3.4 mmol/L。

以上是一种简单的判定方法,在临床上还应全面分析患者其他情况综合判断。

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    2018-12-13 攀少

    感谢分享

    0

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  5. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Fri Oct 27 05:25:32 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 Y—xianghai

    学习了新知识学习了新知识

    0

  6. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Fri Oct 27 05:25:32 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 榄枷檬

    谢谢分享

    0

  7. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Fri Oct 27 05:25:32 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 明月清辉

    谢谢分享.学习了

    0

  8. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Fri Oct 27 05:25:32 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 刘煜

    谢谢分享.阅读

    0

  9. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Fri Oct 27 05:25:32 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 天地飞扬

    谢谢分享!

    0

  10. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Fri Oct 27 05:25:32 CST 2017, time=2017-10-27, status=1, ipAttribution=)]
    2017-10-27 yjs木玉

    好好好好好好好好

    0

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专访|陆信武:颈动脉狭窄需防中风,微创新技术拆除主动脉瘤

主动脉夹层、主动脉瘤,是致死率非常高的疾病,犹如一颗“不定时炸弹”,随时威胁患者生命。近三十年,随着血管外科的兴起,微创介入手术逐渐取代传统的开胸大手术,通过在血管内放置支架来拆除这个随时会破裂的“炸弹”。上海交大医学院附属第九人民医院血管外科主任陆信武教授,就是专注于此类疾病的“拆弹专家”。他带领九院血管外科,在累及弓上分支的主动脉腔内修复术中,创造 “激光原位开窗技术”,取得了初步成果。他

活血通脉片对颈动脉易损斑块的干预作用

活血通脉片和阿司匹林肠溶片、阿托伐他汀钙片联用能提高干预颈动脉易损斑块的效果。

ATVB:颈动脉斑块钙化与斑块内出血相关!

由此可见,颈动脉粥样硬化斑块表面钙化和多个钙化与IPH存在独立相关,提示钙化数量和位置都可能在IPH的发生中起着重要的作用。这些发现可能为理解IPH的机制提供了新的见解。

JACC:体循环肺动脉分流的手术介入治疗

该研究证明颈动脉可作为替代入路,与手术成功率更高,手术时间和支架植入时间更短相关。

开滦研究:半数中老年有颈动脉斑块,近三成不稳定

开滦总医院近日发表的一项研究表明,中老年人群中有54%有颈动脉斑块,其中26%为稳定斑块,28%为不稳定斑块。

悲剧重演,17岁男孩一吻丧命!

说吻痕会致命,一开始我也不信。因为除了外观上会带来的麻烦外,几乎没有任何不适。和普通的淤青一样,3~5天就能消失。但前阵子,有报道称墨西哥一年轻男子,在被可爱的小女友深吻脖子后身亡。禁不住一阵狙翎,三观再次被刷新。