空气污染是胎儿死亡重要风险因素之一

2016-05-26 佚名 来宝网

一项新的评估结果显示,空气污染和胎儿死亡风险增加之间的联系正在不断加强。世界上各地区的胎儿死亡概率差异十分显著,研究小组表民,去年260万死产中的大多数情况,其实是可以预防的。“如果环境空气与胎儿死亡风险增加之间的联系得到证实,那么这将是重大的公共卫生突破,”丹麦哥本哈根大玛丽中心的流行病筛查学专业的 Marie Pedersen 表示,她并没有参与该项研究。先前的研究已经表明


一项新的评估结果显示,空气污染和胎儿死亡风险增加之间的联系正在不断加强。

世界上各地区的胎儿死亡概率差异十分显著,研究小组表民,去年260万死产中的大多数情况,其实是可以预防的。

“如果环境空气与胎儿死亡风险增加之间的联系得到证实,那么这将是重大的公共卫生突破,”丹麦哥本哈根大玛丽中心的流行病筛查学专业的 Marie Pedersen 表示,她并没有参与该项研究。

先前的研究已经表明,空气污染严重和胎儿死亡风险增加之间存在某种联系,但是这种联系十分微弱。但是新的研究为这一关系提供了更深刻的证据,来自芬兰奥卢大学的研究者们对三项2015年进行的来自美国和亚洲的研究进行了分析。

新的研究表明,暴露于空气污染中,尤其是对处于孕期第三阶段的女性来说,胎儿死亡风险显著增加。然而,研究人员表示,该研究并不能证明其中的因果关系,目前仍需要进一步的研究以深入了解其中的联系。

该研究相关文章发表于5月24日的《职业与环境医学》(Occupational & Environmental Medicine)杂志上。同时,Marie Pedersen近年来参与了大量有关空气污染对胎儿的影响,发表了很多研究成果。

“对于全球健康问题来说,胎死腹中是最容易被忽视的悲剧之一,现有的研究证据让我们对这一研究课题提起高度重视,进行详细的研究,找出解决这一悲剧的方案,”他在杂志的一篇社论中写道。

其他影响胎儿死亡风险的因素可能包括:肥胖、感染、酒精、职业和压力等,研究人员表示。这些因素共同构成了胎儿死亡风险因素。

原始出处:

Pedersen M.Is it still important to study if ambient air pollution triggers stillbirth? Occup Environ Med. 2016 May 24. pii: oemed-2016-103625

O'Callaghan-Gordo C, Fthenou E, Pedersen M, Espinosa A, Chatzi L, Beelen R, Chalkiadaki G, Decordier I, Hoek G, Merlo DF, Nieuwenhuijsen M, Roumeliotaki T, Vafeiadi M, Vande Loock K, Kleinjans J, Stephanou E, Kirsch-Volders M, Kogevinas M. Outdoor air pollution exposures and micronuclei frequencies in lymphocytes from pregnant women and newborns in Crete, Greece (Rhea cohort). Environ Res. 2015 Nov;143(Pt A):170-6

Clemente DB, Casas M, Vilahur N, Begiristain H, Bustamante M, Carsin AE, Fernández MF, Fierens F, Gyselaers W, Iñiguez C, Janssen BG, Lefebvre W, Llop S, Olea N, Pedersen M, Pieters N, Santa Marina L, Souto A, Tardón A, Vanpoucke C, Vrijheid M, Sunyer J, Nawrot TS. Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts. Environ Health Perspect. 2016 May;124(5):659-65.

Schembari A, de Hoogh K, Pedersen M, Dadvand P, Martinez D, Hoek G, Petherick ES, Wright J, Nieuwenhuijsen MJ. Ambient Air Pollution and Newborn Size and Adiposity at Birth: Differences by Maternal Ethnicity (the Born in Bradford Study Cohort). Environ Health Perspect. 2015 Nov;123(11):1208-15.

Pedersen M, Mendez MA, Schoket B, Godschalk RW, Espinosa A, Landström A, Villanueva CM, Merlo DF, Fthenou E, Gracia-Lavedan E, van Schooten FJ, Hoek G, Brunborg G, Meltzer HM, Alexander J, Nielsen JK, Sunyer J, Wright J, Kovács K, de Hoogh K, Gutzkow KB, Hardie LJ, Chatzi L, Knudsen LE, Anna L, Ketzel M, Haugen M, Botsivali M, Nieuwenhuijsen MJ, Cirach M, Toledano MB, Smith RB, Fleming S, Agramunt S, Kyrtopoulos SA, Lukács V, Kleinjans JC, Segerbäck D, Kogevinas M. Environmental, dietary, maternal, and fetal predictors of bulky DNA adducts in cord blood: a European mother-child study (NewGeneris). Environ Health Perspect. 2015 Apr;123(4):374-80.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=140944, encodeId=860514094432, content=文章真心很好,感谢作者, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Oct 06 13:48:58 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106603, encodeId=851d106603de, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:50:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92598, encodeId=ecc792598cf, content=环保部门应该负起责任, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 18:52:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87938, encodeId=4c898e93868, content=保护环境,人人有责, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160528/IMG5749A60FD120A3124.jpg, createdBy=65fe1709307, createdName=青荷, createdTime=Tue May 31 22:29:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472502, encodeId=abdd14e25023d, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Sat May 28 08:27:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
    2016-10-06 1e10c84am36(暂无匿称)

    文章真心很好,感谢作者

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=140944, encodeId=860514094432, content=文章真心很好,感谢作者, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Oct 06 13:48:58 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106603, encodeId=851d106603de, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:50:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92598, encodeId=ecc792598cf, content=环保部门应该负起责任, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 18:52:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87938, encodeId=4c898e93868, content=保护环境,人人有责, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160528/IMG5749A60FD120A3124.jpg, createdBy=65fe1709307, createdName=青荷, createdTime=Tue May 31 22:29:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472502, encodeId=abdd14e25023d, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Sat May 28 08:27:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
    2016-08-29 ylzr123

    深度好文,值得学习,赞!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=140944, encodeId=860514094432, content=文章真心很好,感谢作者, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Oct 06 13:48:58 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106603, encodeId=851d106603de, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:50:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92598, encodeId=ecc792598cf, content=环保部门应该负起责任, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 18:52:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87938, encodeId=4c898e93868, content=保护环境,人人有责, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160528/IMG5749A60FD120A3124.jpg, createdBy=65fe1709307, createdName=青荷, createdTime=Tue May 31 22:29:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472502, encodeId=abdd14e25023d, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Sat May 28 08:27:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
    2016-07-10 oo902

    环保部门应该负起责任

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=140944, encodeId=860514094432, content=文章真心很好,感谢作者, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Oct 06 13:48:58 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106603, encodeId=851d106603de, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:50:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92598, encodeId=ecc792598cf, content=环保部门应该负起责任, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 18:52:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87938, encodeId=4c898e93868, content=保护环境,人人有责, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160528/IMG5749A60FD120A3124.jpg, createdBy=65fe1709307, createdName=青荷, createdTime=Tue May 31 22:29:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472502, encodeId=abdd14e25023d, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Sat May 28 08:27:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
    2016-05-31 青荷

    保护环境,人人有责

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=140944, encodeId=860514094432, content=文章真心很好,感谢作者, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Oct 06 13:48:58 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106603, encodeId=851d106603de, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:50:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92598, encodeId=ecc792598cf, content=环保部门应该负起责任, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 18:52:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87938, encodeId=4c898e93868, content=保护环境,人人有责, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160528/IMG5749A60FD120A3124.jpg, createdBy=65fe1709307, createdName=青荷, createdTime=Tue May 31 22:29:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472502, encodeId=abdd14e25023d, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Sat May 28 08:27:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]

相关资讯

J Clin Endocrinol Metab:空气污染可增加心脏病的发病风险

近日来自索罗卡医学中心和本古里安大学的一项新的研究表明,空气污染可增加机体心脏病的发病风险,尤其是糖尿病患者,该研究成果已发表于Journal of Clinical Endocrinology & Metabolism。资深作者Victor Novack博士及其同事发现,空气污染可升高血糖和胆固醇的水平以及其他可增加心脏病发病风险的因素。在美国,心脏病是导致男性和女性死亡的主要原因,每年

每年有4万人因空气污染死亡

RCP和RCPCH指出,空气污染正危害我们的机体健康,每年约有4万人的死亡与空气污染有关。空气污染对我们呼吸系统的影响不是短期影响,而是一个长期问题。 报告指出,从胎儿在子宫内发育开始,空气污染对胎儿的发展有众多危害,包括不利于肺和肾脏的发育、增加流产、心脏病、中风、哮喘、糖尿病、老年痴呆症、肥胖和癌症的风险。 有充足证据表明空气污染与不利于肺部发育,同时增多新发哮喘儿童和成年人的数目,同时研究人

Ca Cau & Con :空气污染与脑肿瘤发生风险

这项研究结果不支持空气污染与脑肿瘤发生风险之间存在相对较强的线性相关。但是高浓度空气氮氧化物与脑肿瘤发生风险增加之间的关联值得关注,脑肿瘤形态学研究可能会产生不同结果。

FASEB:空气污染增加肥胖风险

研究人员进行了一项实验,他们将怀孕小鼠随机分为两组,一组暴露于北京户外空气,另一组小鼠所处环境中含有一个空气过滤器,可去除大部分的空气污染颗粒。研究人员饲喂3-8周后即出现变化。 仅19天后,暴露于北京户外空气的怀孕小鼠的肺和肝脏体积增大,且显示组织炎症的出现。相比暴露于含有空气过滤器的小鼠而言,暴露于北京户外的小鼠血液中低密度脂蛋白胆固醇增加50%、甘油三酯增加46%、总胆固醇增加97%。此外,

JAMA:减轻空气污染可显著减少儿童支气管炎症状

儿童支气管炎的症状是很重要的公共和临床健康问题,对社会产生了极大的疾病负担。而空气污染物是导致支气管炎发生的重要危险因素。本研究旨在确定南加利福尼亚环境空气质量的改善是否与儿童支气管炎症状的减少有关。

Lancet:空气污染加快了冠状动脉钙化的进展

长期暴露于小于2.5微米直径(PM2.5)的细颗粒物和交通相关的空气污染物与心血管风险有关。这些联系背后的疾病过程仍然不明朗。该研究的目的是评估长期暴露于大气污染和冠状动脉钙化和颈总动脉内膜中层厚度进展之间的关联。原始出处:Joel D Kaufman,Sara D Adar,R Graham Barr,et al.Association between air pollution and cor