PLOS ONE:腰围,颈围,腰臀比:哪些是严重肥胖女性理想的心脏代谢风险标志物?

2018-11-10 海北 MedSci原创

颈围是唯一与所有心脏代谢风险标志物(HOMA-IR,呼吸暂停 - 低通气指数,Log甘油三酯/ HDL-c,丙氨酸 - 氨基转移酶,天冬氨酸 - 氨基转移酶,γ-谷氨酰转肽酶)显着相关的标志物。

最近,研究人员分析了严重肥胖结果网络(SOON)队列中所包括的女性(n = 305,年龄43 [34; 53]岁,BMI 44.2 [40.8; 48.2] kg / m2)的数据。其目的如下:(i),以评估不同的人体测量标志物之间的共线性,(ii)比较标志物与高血压,2型糖尿病,阻塞性睡眠呼吸暂停综合征(OSAS)和其他心脏代谢风险之间的关联。
结果显示,髋,腰,颈的围度与BMI相关,共线性较小(r = 0.70,r = 0.59,r = 0.37,p <0.001),而腰臀比无相关性(r = 0.11,p = 0.072)。腰围和颈围与高血压,2型糖尿病和OSAS的单变量逻辑回归显著相关,腰臀比与高血压和2型糖尿病显着相关。髋周长与2型糖尿病呈负相关(OR 0.970(95CI:0.948; 0.991)p = 0.006)。 BMI仅与OSAS相关(OR 1.092(95CI:1.043; 1.143)p <0.001)。颈围是唯一与所有心脏代谢风险标志物(HOMA-IR,呼吸暂停 - 低通气指数,Log甘油三酯/ HDL-c,丙氨酸 - 氨基转移酶,天冬氨酸 - 氨基转移酶,γ-谷氨酰转肽酶)显着相关的标志物。
因此,颈围似乎是最合适的人体测量标记,用于识别与严重肥胖女性高心脏代谢风险相关的脂肪分布。

原始出处:

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    2019-05-22 1235bc3dm63暂无昵称

    了解了

    0

  2. 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    2018-12-05 hukaixun
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encryptionId=8f0085426a7, topicName=腰围)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b0e350, createdName=naiwu77, createdTime=Mon Nov 12 05:15:00 CST 2018, time=2018-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337193, encodeId=285f133e193a1, content=<a href='/topic/show?id=f4c251404aa' target=_blank style='color:#2F92EE;'>#心脏代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51404, encryptionId=f4c251404aa, topicName=心脏代谢)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Mon Nov 12 05:15:00 CST 2018, time=2018-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545993, 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  5. 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encodeId=ab33154599384, content=<a href='/topic/show?id=31a351414ef' target=_blank style='color:#2F92EE;'>#心脏代谢风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51414, encryptionId=31a351414ef, topicName=心脏代谢风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caae13850815, createdName=ms8538335253054589, createdTime=Mon Nov 12 05:15:00 CST 2018, time=2018-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352319, encodeId=dbd8352319a1, content=谢谢分享谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Nov 11 23:24:11 CST 2018, time=2018-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352263, encodeId=869c3522635e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sun Nov 11 11:29:17 CST 2018, time=2018-11-11, status=1, ipAttribution=)]
    2018-11-13 kafei

    了解一下谢谢

    0

  6. 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encryptionId=8f0085426a7, topicName=腰围)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b0e350, createdName=naiwu77, createdTime=Mon Nov 12 05:15:00 CST 2018, time=2018-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337193, encodeId=285f133e193a1, content=<a href='/topic/show?id=f4c251404aa' target=_blank style='color:#2F92EE;'>#心脏代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51404, encryptionId=f4c251404aa, topicName=心脏代谢)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Mon Nov 12 05:15:00 CST 2018, time=2018-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545993, encodeId=ab33154599384, content=<a href='/topic/show?id=31a351414ef' target=_blank style='color:#2F92EE;'>#心脏代谢风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51414, encryptionId=31a351414ef, topicName=心脏代谢风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caae13850815, createdName=ms8538335253054589, createdTime=Mon Nov 12 05:15:00 CST 2018, time=2018-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352319, encodeId=dbd8352319a1, content=谢谢分享谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sun Nov 11 23:24:11 CST 2018, time=2018-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352263, encodeId=869c3522635e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sun Nov 11 11:29:17 CST 2018, time=2018-11-11, status=1, ipAttribution=)]
    2018-11-12 naiwu77
  7. 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  8. 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  9. [GetPortalCommentsPageByObjectIdResponse(id=366607, encodeId=39b136660ed6, content=了解了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96472403201, createdName=1235bc3dm63暂无昵称, createdTime=Wed May 22 19:32:31 CST 2019, time=2019-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1841316, encodeId=3819184131674, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Dec 05 21:15:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), 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createdTime=Sun Nov 11 23:24:11 CST 2018, time=2018-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352263, encodeId=869c3522635e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sun Nov 11 11:29:17 CST 2018, time=2018-11-11, status=1, ipAttribution=)]
    2018-11-11 1e0ece0dm09(暂无匿称)

    谢谢分享谢谢

    0

  10. 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    2018-11-11 医者仁心5538

    学习了

    0

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为什么一些肥胖的人反而不容易得糖尿病?英国埃克塞特大学日前发布的一项新研究显示,人体与肥胖相关的部分遗传变异反而有助降低2型糖尿病、心脏病和中风的风险。

肥胖是否会影响孩子学业及应对能力?

一项初步研究表明,肥胖儿童在课业和应对压力方面可能有额外的困难。在一项对近2.3万名父母的调查中,研究人员发现,与体重正常的同龄人相比,肥胖儿童不太可能表现出某些“繁荣”的迹象。这就意味着孩子们对功课和学习的投入减少了,他们在应对挑战时更加困难。研究人员说,这些发现不一定能证明儿童肥胖助长了这些问题。不过,美国儿科学会(American Academy of Pediatrics)肥胖科主任克里斯

EMBO Mol Med:三医大郑宏庭团队揭示糖尿病与肥胖引致骨骼肌再生障碍新机制

糖尿病和肥胖人群中常见骨骼肌再生过程的损伤,导致肌肉功能的部分丧失。然而,糖尿病和肥胖引致骨骼肌再生障碍的机制尚未得到明确阐述。

Cell Metab:你知道吗?肥胖竟有多种类型,到底哪一种关乎你的健康呢?

如今我们的社会似乎已经接受了这样一种观点,即体重增加是在一个容易摄入卡路里的环境中长大所产生的必然结果,然而在我们的职业和私人生活中,体育锻炼所起到的作用越来越小,而且衰老只会让减肥变得更加困难。

Am J Prev Med:数字化干预措施更有利于低收入肥胖患者减重

发表于American Journal of Preventive Medicine的一项研究显示,与接受常规护理者相比,接受数字化干预措施的低收入、肥胖成人患者在一年内减重更多。

GUT:儿童服用抗生素及抗胃酸药物导致肥胖风险增加

研究发现,2岁以下儿童服用抗生素和胃酸抑制剂导致儿童肥胖症风险增加