Diabetic Med:慢性糖尿病足溃疡的出现与更加频繁和较晚期的视网膜病变有关

2018-11-16 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于慢性糖尿病足溃疡与视网膜病变有关的研究。研究目的是证实糖尿病视网膜病变在一组2型糖尿病和慢性糖尿病足溃疡患者中的频率和严重程度,并与匹配的对照的无性糖尿病足溃疡病史的2型糖尿病患者的视力,视网膜病变水平和临床显著黄斑水肿进行比较。研究人员对90名踝关节以下至少持续3个月的糖尿病足溃疡的白人进行视力和眼底成像评估,并将结果与180例没有慢

近日,国际杂志 《Diabetic Med》上在线发表一项关于慢性糖尿病足溃疡与视网膜病变有关的研究。研究目的是证实糖尿病视网膜病变在一组2型糖尿病和慢性糖尿病足溃疡患者中的频率和严重程度,并与匹配的对照的无性糖尿病足溃疡病史的2型糖尿病患者的视力,视网膜病变水平和临床显著黄斑水肿进行比较。
研究人员对90名踝关节以下至少持续3个月的糖尿病足溃疡的白人进行视力和眼底成像评估,并将结果与180例没有慢性糖尿病足溃疡病史的2型糖尿病白人(对照组)进行比较。对照组的年龄,性别和糖尿病持续时间与实验组相匹配。
尽管年龄和糖尿病持续时间相似,但糖尿病足溃疡组中41%的患者存在严重的非增殖性或增殖性糖尿病视网膜病变,而对照组为15%(P <0.001)。糖尿病足溃疡组中只有6%没有任何糖尿病视网膜病变,而对照组中有34%。增生性糖尿病视网膜病变在糖尿病足溃疡组更常见(31%vs 8%; P <0.001),但增殖期糖尿病视网膜病变时间组间无差异。临床上显著的黄斑水肿更容易出现,并且糖尿病足溃疡组在最佳和最差眼睛视力测试中明显表现出更差的结果。
研究表明,在本研究所涉及北欧地区,几乎所有患有2型糖尿病和慢性糖尿病足溃疡的人患有糖尿病视网膜病变。几乎三分之一患有增生性糖尿病视网膜病变,而匹配对照组<10%。更晚期的糖尿病视网膜病变与视力更差有关。

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    2018-11-18 zutt
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    2018-11-18 hb2008ye
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    2018-11-16 misszhang

    谢谢MedSci提供最新的资讯

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