Obstet Gynecol:女性肛门癌与HPV感染间联系

2016-02-20 Mechront 译 MedSci原创

英国妇女和婴儿医院的研究人员最近发表的一项研究结果显示,肛门癌与人乳头瘤病毒(HPV)感染有关。研究成果发表在Obstetrics & Gynecology。HPV与肛门癌相关,尤其是女性中。2014年,7200例肛门癌患者中有4500例为女性。因此女性既往HPV相关生殖器感染的既往史,将有助于肛门癌的筛查。通常对HIV阳性的男性和女性,以及男男性行为者进行肛门细胞学检查以筛查肛门癌。宫颈

英国妇女和婴儿医院的研究人员最近发表的一项研究结果显示,肛门癌与人乳头瘤病毒(HPV)感染有关。研究成果发表在Obstetrics & Gynecology。

HPV与肛门癌相关,尤其是女性中。2014年,7200例肛门癌患者中有4500例为女性。因此女性既往HPV相关生殖器感染史,将有助于肛门癌的筛查。

通常对HIV阳性的男性和女性,以及男男性行为者进行肛门细胞学检查以筛查肛门癌。宫颈、阴道或外阴癌女性有5倍的肛门癌风险,而这些生殖器癌症均与HPV感染相关。因此研究者进行了一项研究,探究对HIV阴性的女性进行HPV检测和肛门细胞学检查的可行性。

该研究在2012年12月到2014年2月间对273名女性进行了肛门细胞学和HPV基因检测。肛门细胞学检查异常的女性进行高分辨率的肛门镜检查,由结直肠外科医生合作参与活检检查。

根据不同癌症风险将273名参与者分为两组,高风险组指累积宫颈癌、阴道癌和外阴癌的女性,低风险组则没有癌症史、发育不良或异常的巴氏涂片。

高风险和低风险组中肛门细胞学检查异常的发生率分别为40%和21.7%;两组高危HPV的发现率分别为20.8%和1.2%。


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原始出处:


Anal Cytology and Human Papillomavirus Genotyping in Women With a History of Lower Genital Tract Neoplasia Compared With Low-Risk Women.
Robison, Katina MD; et al. Obstetrics & Gynecology. DOI.10.1097/AOG.0000000000001135. Published December 2015 - Volume 126 - Issue 6 - p 1294–1300.

Study demonstrates connection between anal cancer and HPV

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    2016-10-25 yhy100200
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    2016-07-23 hxj0127
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    2016-02-28 jetleo

    宫颈癌风险也大

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=2011235, encodeId=97c32011235b6, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Tue Oct 25 20:08:00 CST 2016, time=2016-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043899, encodeId=dd9120438992e, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat Jun 18 18:08:00 CST 2016, time=2016-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693696, encodeId=7862169369606, content=<a href='/topic/show?id=c8168114412' target=_blank style='color:#2F92EE;'>#肛门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81144, encryptionId=c8168114412, topicName=肛门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=39bc29444908, createdName=hxj0127, createdTime=Sat Jul 23 07:08:00 CST 2016, time=2016-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=66213, encodeId=bd4266213f6, content=宫颈癌风险也大, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Sun Feb 28 20:36:00 CST 2016, time=2016-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483032, encodeId=f59f1483032db, content=<a href='/topic/show?id=0ac39080cc' target=_blank style='color:#2F92EE;'>#HPV感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9080, encryptionId=0ac39080cc, topicName=HPV感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=56437868203, createdName=ms3415360956839622, createdTime=Mon Feb 22 07:08:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65063, encodeId=66606506344, content=及网友?, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d81686303, createdName=1de4881fm22(暂无匿称), createdTime=Sun Feb 21 14:50:00 CST 2016, time=2016-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65022, encodeId=15516502265, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=5, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHfSLw3PzIKiaSnTBUuAtRkrrxWpibukl35iciaGtBq4LYQv4ian1tPC3IdmzWI2dZ3cDC8wUg5CnBxlJ/0, createdBy=33a51675735, createdName=jiangxianchen, createdTime=Sun Feb 21 08:45:00 CST 2016, time=2016-02-21, status=1, ipAttribution=)]
    2016-02-21 1de4881fm22(暂无匿称)

    及网友?

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2011235, encodeId=97c32011235b6, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Tue Oct 25 20:08:00 CST 2016, time=2016-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043899, encodeId=dd9120438992e, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat Jun 18 18:08:00 CST 2016, time=2016-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693696, encodeId=7862169369606, content=<a href='/topic/show?id=c8168114412' target=_blank style='color:#2F92EE;'>#肛门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81144, encryptionId=c8168114412, topicName=肛门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=39bc29444908, createdName=hxj0127, createdTime=Sat Jul 23 07:08:00 CST 2016, time=2016-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=66213, encodeId=bd4266213f6, content=宫颈癌风险也大, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Sun Feb 28 20:36:00 CST 2016, time=2016-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483032, encodeId=f59f1483032db, content=<a href='/topic/show?id=0ac39080cc' target=_blank style='color:#2F92EE;'>#HPV感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9080, encryptionId=0ac39080cc, topicName=HPV感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=56437868203, createdName=ms3415360956839622, createdTime=Mon Feb 22 07:08:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65063, encodeId=66606506344, content=及网友?, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d81686303, createdName=1de4881fm22(暂无匿称), createdTime=Sun Feb 21 14:50:00 CST 2016, time=2016-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65022, encodeId=15516502265, content=嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=5, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHfSLw3PzIKiaSnTBUuAtRkrrxWpibukl35iciaGtBq4LYQv4ian1tPC3IdmzWI2dZ3cDC8wUg5CnBxlJ/0, createdBy=33a51675735, createdName=jiangxianchen, createdTime=Sun Feb 21 08:45:00 CST 2016, time=2016-02-21, status=1, ipAttribution=)]
    2016-02-21 jiangxianchen

    0

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