PLoS One: 卒中后睡眠呼吸障碍与卒中部位无关?

2017-04-22 phylis MedSci原创

缺血性脑卒中患者睡眠呼吸障碍(SRBD)很常见,且与不良预后相关。卒中后SRBD可能是中枢神经系统具体结构损伤的一个直接后果。然而,是否缺血性卒中的具体位置引起SRBD是尚不清楚。因此研究者研究了SRBD与缺血性病变部位的关系。方法:卒中单元治疗的急性缺血性卒中患者纳入前瞻性观察研究。所有患者在卒中急性期均行磁共振成像(MRI)和多导图睡眠监测。SRBD是指睡眠呼吸暂停低通气指数(AHI)≥10。

缺血性脑卒中患者睡眠呼吸障碍(SRBD)很常见,且与不良预后相关。卒中后SRBD可能是中枢神经系统具体结构损伤的一个直接后果。然而,是否缺血性卒中的具体位置引起SRBD是尚不清楚。因此研究者研究了SRBD与缺血性病变部位的关系。

方法:卒中单元治疗的急性缺血性卒中患者纳入前瞻性观察研究。所有患者在卒中急性期均行磁共振成像(MRI)和多导图睡眠监测。SRBD是指睡眠呼吸暂停低通气指数(AHI)≥10。应用MRI标准影像图确定,存在或不存在SRBD的卒中患者梗死部位的可能分布情况。采用Logistic回归分析进行组间比较。

结果:共纳入142名患者,86(59%)例患者存在SRBD。SRBD组患者年龄、体重指数和高血压高于非SRBD组。梗死部位与SRBD之间无统计学意义。

结论:研究显示脑卒中患者脑卒中部位与SRBD无相关性,而SRBD的风险因素与SRBD显著相关。鉴于脑卒中患者SRBD的高患病率,这些研究结果表明,SRBD的发生不是由中枢神经系统结构的损伤引起,可能是卒中患者存在SRBD的危险因素。研究结果可以用来确定从多导图睡眠监测中获益的卒中患者。

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    2017-05-30 海棠胜雪

    学习了,谢谢分享

    0

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