J Hypertens:适度运动时过度收缩压升高可识别左心室肥厚高风险的高血压患者!

2018-03-09 xing.T MedSci原创

由此可见,适度运动时收缩压过高可用于鉴别LVH发展的高危高血压患者。

高血压患者在运动过程中表现出过度的收缩压升高,尽管需要最佳的血压(BP)控制来防止左心室肥厚(LVH)的发展。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,这项研究评估了中度运动时过度收缩压升高是否与新发LVH有关。

该研究共纳入了143例无LVH的患者,这些患者服用抗高血压药治疗BP一直保持低于140/90mmHg,受试者在运动时进行中等强度的踏车运动试验来评估SBP升高(ΔSBP)。采用超声心动图检查每年评估一次左心室重量指数(LVMI)以确定新发左心室肥厚。根据ΔSBP三分位数,患者被分为三组。研究人员通过Kaplan–Meier法、对数秩检验法和Cox回归分析评估了ΔSBP与新发LVH之间的关系。

患者(100例男性,65.3±9.1岁)静息时血压为126±16/75±11mmHg。随访2.5±1.6年,新发LVH 有47例(32.9%)。较高的ΔSBP与LVH较高的发生率显著相关(P<0.001):最低、中等和最高三组分别为12.8、27.1和58.3%。在多变量分析中,ΔSBP是新发LVH的显著预测因素(ΔSBP每增加10mmHg的风险比为1.45;95%可信区间为1.22-1.73;P<0.001)。与最低水平比较,中间和最高三分位数组LVH发生率的风险比别为3.16(95%可信区间为1.07-9.32)和6.43(95%可信区间为2.35-17.62)。

由此可见,适度运动时收缩压过高可用于鉴别LVH发展的高危高血压患者。

原始出处:


Tanaka, Shinya.et al. Excessive SBP elevation during moderate exercise discriminates patients at high risk of developing left ventricular hypertrophy from hypertensive patients.Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/Excessive_SBP_elevation_during_moderate_exercise.97515.aspx

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    2018-05-03 feather89
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  9. 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    2018-03-10 flysky120

    高血压运动与左心室肥厚

    0

  10. 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    2018-03-09 139****5926

    好好文章学习了

    0

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