炎症性肠病(IBD)患者确诊后脊椎关节病发病率逐年增加

2012-07-12 吴莹莹 爱唯医学网

根据首项分析炎症性肠病(IBD)患者的脊椎关节病发病情况的人群研究结果,在诊断IBD后10年内,脊椎关节病的累计发病率为1/50,在诊断IBD后20和30年,发病率分别攀升到1/25和1/14。明尼苏达州罗彻斯特市梅奥医院风湿科主任Matteson医生及其同事分析了明尼苏达州Olmsted县1970~2004年间被诊断为IBD的居民的医疗记录。有311人被诊断为克罗恩氏病,365人被诊断为溃疡性结

根据首项分析炎症性肠病(IBD)患者的脊椎关节病发病情况的人群研究结果,在诊断IBD后10年内,脊椎关节病的累计发病率为1/50,在诊断IBD后20和30年,发病率分别攀升到1/25和1/14。

明尼苏达州罗彻斯特市梅奥医院风湿科主任Matteson医生及其同事分析了明尼苏达州Olmsted县1970~2004年间被诊断为IBD的居民的医疗记录。有311人被诊断为克罗恩氏病,365人被诊断为溃疡性结肠炎,对这些患者随访至2011年6月。诊断IBD时的中位年龄为33岁。

结果显示,在IBD之前被诊断为脊椎关节病的比例为1%。在确诊IBD后10年、20年和30年,脊椎关节病的累计发病率分别为2.3%、4.2%和7.1%。诊断IBD后10年时,强直性脊柱炎的累计发病率为0.2%,在诊断后20年升至0.7%。在诊断克罗恩氏病后10、20和30年,脊椎关节病的累计发病率分别为2.6%、6.1%和 9.8%;在诊断溃疡性结肠炎后10、20和30年,脊椎关节病的累计发病率分别为1.9%、2.8%和4.9%。

诊断IBD后才出现的脊椎关节病临床特征包括:少关节炎(3.1%)、多关节炎(1.3%)、骶髂关节炎(1.6%)、银屑病(2.2%)、葡萄膜炎(2.9%)、足底筋膜炎(5%)。

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    2012-07-14 bnurmamat
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    2012-07-14 neizongke

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