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Stroke：左室收缩功能障碍不影响心衰患者栓塞事件风险

2015-02-10 高晓方 译 医学论坛网

心衰左室收缩功能障碍栓塞
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加拿大一项研究表明，在心衰患者中，无论时左室收缩功能障碍(LVSD)存在与否或症状严重度均对栓塞事件风险无影响。论文1月27日在线发表于《卒中》(Stroke)杂志。 此项研究共纳入3487例接受抗血小板治疗的心衰患者，并将其分类为射血分数正常和降低者。如射血分数降低，则将LVSD分类为轻、中或重度。利用NYHA对症状进行定量评估。主要转归由卒中、短暂性脑缺血发作和系统性栓塞组成。

加拿大一项研究表明，在心衰患者中，无论时左室收缩功能障碍(LVSD)存在与否或症状严重度均对栓塞事件风险无影响。论文1月27日在线发表于《卒中》(Stroke)杂志。


此项研究共纳入3487例接受抗血小板治疗的心衰患者，并将其分类为射血分数正常和降低者。如射血分数降低，则将LVSD分类为轻、中或重度。利用NYHA对症状进行定量评估。主要转归由卒中、短暂性脑缺血发作和系统性栓塞组成。

结果显示，射血分数正常和降低的患者分别为969例(46.8%)和1103例(53.2%)。在平均3.6年的随访期间，386例患者出现首发卒中、短暂性脑缺血发作或系统性栓塞。

系统性栓塞的最显著独立预测因素为年龄≥75岁、既往卒中或短暂性脑缺血发作以及女性。然而，射血分数<0.5、LVSD程度和NYHA分类不能预测栓塞事件。射血分数正常和降低患者的栓塞事件风险相似(4.3%对4.4%)。在LVSD和NYHA各分类患者中栓塞事件风险亦相似。

原始出处：

Sandhu RK1, Hohnloser SH2, Pfeffer MA2, Yuan F2, Hart RG2, Yusuf S2, Connolly SJ2, McAlister FA2, Healey JS2.Relationship Between Degree of Left Ventricular Dysfunction, Symptom Status, and Risk of Embolic Events in Patients With Atrial Fibrillation and Heart Failure.Stroke. 2015 Jan 27. pii: STROKEAHA.114.007140. [Epub ahead of print]、

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    2015-03-16 ms306040998833292

    #栓塞事件#

    0

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    2015-08-01 经常头晕

    #收缩功能障碍#

    0

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    2015-10-13 fengyqf

    #左室收缩功能障碍#

    0

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    2015-02-17 chinayinhan

    已阅

    0

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    2015-02-16 windmilL1989

    音音

    0

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    2015-02-15 jianlion

    哦

    0

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    2015-02-12 yuanming7

    #心衰患者#

    0

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    2015-02-12 naiwu78

    #功能障碍#

    0

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