即刻起效,仅需超声引导!葛均波院士等报告自主研发ValveClamp治疗二尖瓣反流经验

2020-06-09 朱朱 中国循环杂志

复旦大学附属中山医院葛均波院士、潘翠珍教授等发表的一项研究显示,利用我国自主研发的二尖瓣介入器械ValveClamp对退行性二尖瓣反流患者行经导管缘对缘修复术时,术后即刻二尖瓣几何形状就有明显改善。

复旦大学附属中山医院葛均波院士、潘翠珍教授等发表的一项研究显示,利用我国自主研发的二尖瓣介入器械ValveClamp对退行性二尖瓣反流患者行经导管缘对缘修复术时,术后即刻二尖瓣几何形状就有明显改善,二尖瓣反流明显减轻。
 
ValveClamp的原始创意由葛均波院士团队提出,是一种国内企业自主研发的、全球首个经心尖二尖瓣夹合器,其操作方式简单,不需要X射线,仅由超声引导就能完成手术。

该研究一共纳入35例有症状的3~4级以上退行性二尖瓣反流患者,这些患者均在经食道三维超声心动图引导下进行ValveClamp植入术。
 
超声显示,术后即刻,患者的平均二尖瓣环前后径由33.24 mm缩小至31.12 mm,平均二尖瓣脱垂高度由4.78 mm减至2.32 mm,平均二尖瓣叶总裸露面积从1110.29 mm2缩小至1013.44 mm2
 
与此同时,二尖瓣反流程度明显减轻。
 
多因素分析显示,术后二尖瓣反流减轻与二尖瓣环前后径和二尖瓣脱垂高度减小有关。
 
2018年,葛院士团队利用ValveClamp,成功完成全球首例经心尖二尖瓣夹合术。
 
来源:Effect of a Novel Transcatheter Edge-To-Edge Repair Device on the Three-Dimensional Geometry of Mitral Valve in Degenerative Mitral Regurgitation. Catheter Cardiovasc Interv, 2020 Jun 4. 

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    2020-11-28 lxg951
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topicList=[TopicDto(id=18270, encryptionId=e08d182e056, topicName=valve)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=09a12500213, createdName=12498f1em08(暂无昵称), createdTime=Mon Nov 16 11:37:39 CST 2020, time=2020-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1813480, encodeId=77e5181348089, content=<a href='/topic/show?id=0ba692e7473' target=_blank style='color:#2F92EE;'>#超声引#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92774, encryptionId=0ba692e7473, topicName=超声引)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb182500058, createdName=yuhaisheng_ibp_32061711, createdTime=Thu Aug 20 20:37:39 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1300397, encodeId=1f2f130039e0f, content=<a href='/topic/show?id=ed5ee332423' target=_blank style='color:#2F92EE;'>#研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73324, encryptionId=ed5ee332423, topicName=研发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463287, encodeId=23b7146328ee5, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571688, encodeId=c5a015e168865, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=220d15750403, createdName=feifers, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626293, encodeId=1ec4162629384, content=<a href='/topic/show?id=44ca88222d2' target=_blank style='color:#2F92EE;'>#葛均波院士#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88222, encryptionId=44ca88222d2, topicName=葛均波院士)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63720999381, createdName=hjwang86, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1049231, encodeId=2cc410492310e, content=院士是学术至高点,也是大家必争之地呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Tue Jun 09 19:37:39 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1672184, encodeId=7dba16e21840d, content=<a href='/topic/show?id=177c85966dc' target=_blank style='color:#2F92EE;'>#自主研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85966, encryptionId=177c85966dc, topicName=自主研发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d2c26890289, createdName=xlwang2700, createdTime=Thu Feb 25 17:37:39 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769829, encodeId=42cb1e698290d, content=<a href='/topic/show?id=b3fc92e7516' target=_blank style='color:#2F92EE;'>#超声引导#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92775, encryptionId=b3fc92e7516, topicName=超声引导)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d66e38113145, createdName=guoyibin, createdTime=Sun Nov 01 11:37:39 CST 2020, time=2020-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057682, encodeId=76a6205e68240, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sat Nov 28 16:37:39 CST 2020, time=2020-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796687, encodeId=6a1e1e9668764, content=<a href='/topic/show?id=e08d182e056' target=_blank style='color:#2F92EE;'>#valve#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, 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style='color:#2F92EE;'>#研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73324, encryptionId=ed5ee332423, topicName=研发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463287, encodeId=23b7146328ee5, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), 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createdBy=a63720999381, createdName=hjwang86, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1049231, encodeId=2cc410492310e, content=院士是学术至高点,也是大家必争之地呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Tue Jun 09 19:37:39 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1672184, encodeId=7dba16e21840d, content=<a href='/topic/show?id=177c85966dc' target=_blank style='color:#2F92EE;'>#自主研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85966, encryptionId=177c85966dc, topicName=自主研发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d2c26890289, createdName=xlwang2700, createdTime=Thu Feb 25 17:37:39 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769829, encodeId=42cb1e698290d, content=<a href='/topic/show?id=b3fc92e7516' target=_blank style='color:#2F92EE;'>#超声引导#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92775, encryptionId=b3fc92e7516, topicName=超声引导)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d66e38113145, createdName=guoyibin, createdTime=Sun Nov 01 11:37:39 CST 2020, time=2020-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057682, encodeId=76a6205e68240, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sat Nov 28 16:37:39 CST 2020, time=2020-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796687, encodeId=6a1e1e9668764, content=<a href='/topic/show?id=e08d182e056' target=_blank style='color:#2F92EE;'>#valve#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, 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style='color:#2F92EE;'>#研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73324, encryptionId=ed5ee332423, topicName=研发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463287, encodeId=23b7146328ee5, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571688, encodeId=c5a015e168865, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=220d15750403, createdName=feifers, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626293, encodeId=1ec4162629384, content=<a href='/topic/show?id=44ca88222d2' target=_blank style='color:#2F92EE;'>#葛均波院士#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88222, encryptionId=44ca88222d2, topicName=葛均波院士)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63720999381, createdName=hjwang86, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1049231, encodeId=2cc410492310e, content=院士是学术至高点,也是大家必争之地呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Tue Jun 09 19:37:39 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
    2020-06-11 lqvr
  7. [GetPortalCommentsPageByObjectIdResponse(id=1672184, encodeId=7dba16e21840d, content=<a href='/topic/show?id=177c85966dc' target=_blank style='color:#2F92EE;'>#自主研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85966, encryptionId=177c85966dc, topicName=自主研发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d2c26890289, createdName=xlwang2700, createdTime=Thu Feb 25 17:37:39 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769829, encodeId=42cb1e698290d, content=<a href='/topic/show?id=b3fc92e7516' target=_blank style='color:#2F92EE;'>#超声引导#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92775, encryptionId=b3fc92e7516, topicName=超声引导)], attachment=null, authenticateStatus=null, createdAvatar=null, 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style='color:#2F92EE;'>#研发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73324, encryptionId=ed5ee332423, topicName=研发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463287, encodeId=23b7146328ee5, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571688, encodeId=c5a015e168865, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=220d15750403, createdName=feifers, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626293, encodeId=1ec4162629384, content=<a href='/topic/show?id=44ca88222d2' target=_blank style='color:#2F92EE;'>#葛均波院士#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88222, encryptionId=44ca88222d2, topicName=葛均波院士)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63720999381, createdName=hjwang86, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1049231, encodeId=2cc410492310e, content=院士是学术至高点,也是大家必争之地呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Tue Jun 09 19:37:39 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
    2020-06-11 wwzzly
  8. 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createdBy=a63720999381, createdName=hjwang86, createdTime=Thu Jun 11 07:37:39 CST 2020, time=2020-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1049231, encodeId=2cc410492310e, content=院士是学术至高点,也是大家必争之地呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Tue Jun 09 19:37:39 CST 2020, time=2020-06-09, status=1, ipAttribution=)]
    2020-06-11 feifers
  9. 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  10. 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    2020-06-09 junJUN

    院士是学术至高点,也是大家必争之地呀

    0

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