Arthritis Rheumatol:当前贫困、贫困史和脱离贫困对SLE患者疾病损害积累的影响!

2017-05-29 xing.T MedSci原创

目前处于贫困、贫困的程度和脱离贫困的对SLE损伤的影响表明,贫困在SLE患者积累损害中起着关键作用。

近日,风湿疾病领域权威杂志Arthritis & Rheumatology上发表了一篇研究文章,研究人员旨在评估当前贫困、贫困年数和脱离贫困对系统性红斑狼疮(SLE)患者疾病损伤累积的影响。

研究人员对783例SLE患者从2003年至2015年通过年度结构化面试来进行随访。受访者每年会被根据家庭收入≤联邦贫困水平的125%来进行分类。线性和logistic回归分析被用来评估2009年贫困、在2003年至2009年期间贫困年数以及2009年永久性地脱离贫困对疾病损害程度或到2015年具有临床意义的疾病损害积累的影响。

在调整了社会人口统计学、健康行为和保健特点后,研究人员发现2009年处于贫困与2015年累计损伤水平的增加相关(0.62分,95%可信区间为0.25-0.98),并且具有临床意义的疾病损害的几率增加(比值比为1.67,95%可信区间为0.98-2.85)。在2003年至2009年期间每年贫困与更大的疾病损害相关(2.45,95%可信区间为1.88-3.01),相比于贫困年半或以上(1.45,95%可信区间为0.97-1.93)、贫穷不到半年(1.49,95%可信区间为1.0-1.10),或不到一年(1.34,95%可信区间为1.20-1.50)。那些永久脱离贫困的参与者有着类似的损害增加(1.30,95%可信区间为0.90-1.69),正如那些从来没有贫困的参与者一样(1.36,95%可信区间为1.23-1.50),但比那些仍然处于贫困的参与者损害要少得多(1.98,95%可信区间为1.59-2.38)。

目前处于贫困、贫困的程度和脱离贫困的对SLE损伤的影响表明,贫困在SLE患者积累损害中起着关键作用。

原始出处:


Edward Yelin, et al. A Prospective Study of the Impact of Current Poverty, History of Poverty, and Exiting Poverty on Accumulation of Disease Damage in SLE. Arthritis & Rheumatology.2017. http://onlinelibrary.wiley.com/doi/10.1002/art.40134/full

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    2017-05-31 zhaojie88
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    2017-05-29 daiyaozu

    学习了,不错

    0

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