Medicine :糖尿病与卒中、卒中后不良预后相关

2016-01-12 phylis 译 MedSci原创

先前研究表明糖尿病患者卒中发生风险增加,但这些研究存在一些限制。研究者进行这项研究更好的了解糖尿病患者卒中发生的风险及卒中后预后。这项回顾性队列研究,从台湾国家健康保险索赔数据库中,识别2000年至2003年间,24027名新诊断的糖尿病患者,及96108名无糖尿病的成人。在2000年到2008年的随访期间,确定卒中事件(出血,缺血和其他类型的卒中)的发生及糖尿病相关的卒中校正风险。记录2000年

先前研究表明糖尿病患者卒中发生风险增加,但这些研究存在一些限制。研究者进行这项研究是为了更好地了解糖尿病患者卒中发生的风险及卒中后预后。

这项回顾性队列研究,从台湾国家健康保险索赔数据库中,识别2000年至2003年间,24027名新诊断的糖尿病患者,及96108名无糖尿病的成人。在2000年到2008年的随访期间,确定卒中事件(出血性、缺血性卒中和其他类型的卒中)的发生及糖尿病相关的卒中校正风险。记录2000年到2009年221254例住院脑卒中患者(包括脑出血、脑缺血、其他类型)。计算糖尿病患者和非糖尿病患者卒中后住院的不良事件的校正OR值和95%CI。

糖尿病患者和非糖尿病患者卒中发生率分别为10.1和4.5每1000人-年。随访期间,糖尿病患者(aHR:1.75;95%CI:1.64-1.86)比非糖尿病患者卒中发生的风险更高。性别和各年龄组间糖尿病和卒中发生风险相关是显著的。糖尿病与卒中后死亡(OR:1.33;95%CI:1.19-1.49),肺炎(OR:1.30;95%CI:1.20-1.42)和泌尿系感染(OR:1.66;95%CI:1.55-1.77)相关。

糖尿病与脑卒中后不良事件相关,特别是与糖尿病相关的并发症。糖尿病与卒中风险相关,糖尿病患者卒中后的不良事件和随后的死亡率发生增加。

原文出处:

Liao CC, Shih CC, et al. Impact of Diabetes on Stroke Risk and Outcomes: Two Nationwide Retrospective Cohort Studies. Medicine (Baltimore). 2015 Dec

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    2016-02-26 kalseyzl
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    2016-09-30 jeanqiuqiu
  4. [GetPortalCommentsPageByObjectIdResponse(id=1671230, encodeId=aef316e123047, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Wed Nov 30 09:34:00 CST 2016, time=2016-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773524, encodeId=59c81e7352462, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Fri Feb 26 16:34:00 CST 2016, time=2016-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858652, encodeId=2f681858652ed, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Fri Sep 30 10:34:00 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71784, encodeId=3c08e1784ce, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71785, encodeId=ff8ee1785fe, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71786, encodeId=3a7ae178606, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71787, encodeId=afb4e17879c, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=163, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71788, encodeId=d582e1788c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71789, encodeId=bc8ae1789ba, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336333, encodeId=5f1813363335e, content=<a href='/topic/show?id=071820530c5' target=_blank style='color:#2F92EE;'>#不良预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20530, encryptionId=071820530c5, topicName=不良预后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Thu Jan 14 11:34:00 CST 2016, time=2016-01-14, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1671230, encodeId=aef316e123047, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Wed Nov 30 09:34:00 CST 2016, time=2016-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773524, encodeId=59c81e7352462, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Fri Feb 26 16:34:00 CST 2016, time=2016-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858652, encodeId=2f681858652ed, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Fri Sep 30 10:34:00 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71784, encodeId=3c08e1784ce, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71785, encodeId=ff8ee1785fe, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71786, encodeId=3a7ae178606, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71787, encodeId=afb4e17879c, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=163, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71788, encodeId=d582e1788c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71789, encodeId=bc8ae1789ba, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336333, encodeId=5f1813363335e, content=<a href='/topic/show?id=071820530c5' target=_blank style='color:#2F92EE;'>#不良预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20530, encryptionId=071820530c5, topicName=不良预后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Thu Jan 14 11:34:00 CST 2016, time=2016-01-14, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1671230, encodeId=aef316e123047, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Wed Nov 30 09:34:00 CST 2016, time=2016-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773524, encodeId=59c81e7352462, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Fri Feb 26 16:34:00 CST 2016, time=2016-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858652, encodeId=2f681858652ed, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Fri Sep 30 10:34:00 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71784, encodeId=3c08e1784ce, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71785, encodeId=ff8ee1785fe, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71786, encodeId=3a7ae178606, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71787, encodeId=afb4e17879c, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=163, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71788, encodeId=d582e1788c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71789, encodeId=bc8ae1789ba, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 07:26:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336333, encodeId=5f1813363335e, content=<a href='/topic/show?id=071820530c5' target=_blank style='color:#2F92EE;'>#不良预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20530, encryptionId=071820530c5, topicName=不良预后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Thu Jan 14 11:34:00 CST 2016, time=2016-01-14, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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BMJ Open :早早减肥,远离糖尿病

2016年1月11日讯/生物谷BIOON/一项新的研究说,如果肥胖的年轻人在中年之前可以改变一些不良习惯,那么他们就有机会避免威胁生命的疾病。 这项研究比较了肥胖者年轻和中年时的身体质量指数(BMI),观察肥胖是否会影响他们心脏病,中风或糖尿病发作的风险。 研究结果显示,如果男性在21岁时BMI值很高,但在他们50岁时BMI值降低了,这与年轻时体重正常的人得糖尿病的几率相似或比他们更低。 该

eLife:靶向衰老细胞 阻止干细胞紊乱和糖尿病

最近,来自美国梅奥诊所的研究人员在阻止和逆转衰老相关干细胞紊乱和代谢疾病方面迈出重要一步。他们在这项研究中发现了改善正常衰老小鼠体内上述问题的新方法。相关研究结果发表在国际学术期刊eLife上。   文章作者James Kirkland表示:"我们的工作表明通过特定药物靶向老年人体内的衰老细胞,阻止衰老细胞释放毒性蛋白促进糖尿病和干细胞紊乱的发生,这是完全可能的。"  

Journal of Diabetes:招募年轻审稿人

小编在朋友圈看到Journal of Diabetes(JDB)招募审稿人的消息,觉得对我们MedSci的粉丝来说,真是既靠谱又实用,所以特地告诉大家一声,如果您身边有合适的人选,也可以转发给他们看看哦。以下是原文内容:Journal of Diabetes (http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1753-0