JCLA:血液学参数与钩虫病的相关性:回顾性研究

2019-07-15 gladiator MedSci原创

本研究的目的是确定血液学参数(中性粒细胞‐淋巴细胞比值[NLR]、血小板‐淋巴细胞比值[PLR]、嗜酸性粒细胞‐淋巴细胞比值[ELR])与钩虫病之间的关系。 本研究纳入140例钩虫病患者和159例健康对照者。所有数据均来自广西医科大学第一附属医院电子病历。 钩虫病患者NLR、PLR、ELR水平明显高于健康对照组(均P = 0.000)。建立ROC工作特性曲线,评估这三个血液学参数的诊断

本研究的目的是确定血液学参数(中性粒细胞‐淋巴细胞比值[NLR]、血小板‐淋巴细胞比值[PLR]、嗜酸性粒细胞‐淋巴细胞比值[ELR])与钩虫病之间的关系。

本研究纳入140例钩虫病患者和159例健康对照者。所有数据均来自广西医科大学第一附属医院电子病历。

钩虫病患者NLRPLRELR水平明显高于健康对照组(P = 0.000)。建立ROC工作特性曲线,评估这三个血液学参数的诊断效果。ELR (AUC = 0.850;敏感性= 75.00%;特异性= 86.80%AUC优于NLR (AUC = 0.718;敏感性= 53.57%;特异性= 88.68%PLR (AUC = 0.806;敏感性= 68.57%;特异性= 86.79%)。采用所选指标(RBCELR)建立多元回归模型,模型的敏感性和特异性分别达到82.86%96.23%。在钩虫病患者组,NLR (r = - 0.452, P = 0.000)PLR (r = - 0.357, P = 0.000)与嗜酸性粒细胞呈负相关。

三个血液学参数(NLRPLRELR)的预处理水平可以作为区分钩虫病患者和健康对照组的有价值的指标。NLRPLR与嗜酸性粒细胞这一指标呈负相关。

原始出处:

Zuojian Hu, Huaping Chen , Correlation between hematological parameters and ancylostomiasis: A retrospective study

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    2019-07-17 hxq78318
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    2019-07-17 逆鳞⊙ω⊙

    学习了

    0

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    2019-07-16 phoebeyan520

    学习了

    0

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    2019-07-16 phoebeyan520

    学习了

    0

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    2019-07-16 深海的鱼

    学习学习啊!

    0

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