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国家自然科学基金重大项目“白血病状态下正常造血干/祖细胞的生物学行为及其调控机制”结题验收会议顺利召开

2015-02-13 熊维宁 彭宏凌 江虎军 医学科学部

重大项目白血病造血干细胞
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国家自然科学基金重大项目“白血病状态下正常造血干/祖细胞的生物学行为及其调控机制”验收会议于2015年2月2日在天津召开。国家自然科学基金委员会医学科学部孙瑞娟副主任到会并介绍了重大项目的定位、总体目标、实施管理要求、以及项目验收工作的重点。由9位来自全国不同单位的专家组成的验收组认真听取了项目负责人和课题负责人的汇报，讨论并形成了结题验收意见。 该重大项目的负责人由中国医学科学院血液病研究所程

国家自然科学基金重大项目“白血病状态下正常造血干/祖细胞的生物学行为及其调控机制”验收会议于2015年2月2日在天津召开。国家自然科学基金委员会医学科学部孙瑞娟副主任到会并介绍了重大项目的定位、总体目标、实施管理要求、以及项目验收工作的重点。由9位来自全国不同单位的专家组成的验收组认真听取了项目负责人和课题负责人的汇报，讨论并形成了结题验收意见。

该重大项目的负责人由中国医学科学院血液病研究所程涛教授担任，联合中国人民解放军第二军医大学王建民教授，华中科技大学周剑锋教授，上海交通大学诸江教授共同承担，共设置了四个课题：1. 正常造血干/祖细胞在白血病体内的受抑规律；2. 治疗性干预对白血病机体内正常HSC/HPC数量和功能的影响；3. 白血病细胞特异性分子靶点对正常造血干/祖细胞的作用研究；4. 白血病状态下造血微环境的改变及机制研究。

四年来，该项目取得了多项重要成果，包括：1.利用重编程，染色体重组等技术建立了多种白血病小鼠模型及急性移植物抗宿主病小鼠模型；2. 利用组学方法及单细胞技术揭示了调控白血病恶性克隆生长和正常造血干/祖细胞受抑的重要信号通路，关键分子靶点及表观遗传学的调控机制；3.研究不同类型白血病微环境的特征及特定微环境对白血病细胞，正常干、祖细胞的调控机制，提出促炎能力是白血病起始细胞基本生物特性之一；4.针对重要信号通路和关键分子靶点设计、合成多种小分子化合物，阐明作用机制，提出了在体内选择性抑制白血病细胞生长的治疗策略。目前已在包括Nature Genetics，Nature Communication，Blood，Leukemia，Molecular Cell，Immunity，JCI，JNCI和Autophage等高水平杂志发表相关SCI论文70篇，申请专利5项，成功举办国际会议6次，并培养博士/硕士84名，博士后3名，促进了血液学科的队伍和平台建设。专家组一致认为：该项目全面完成既定目标，结题验收予以通过，综合评价为特优。


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    2015-04-28 lujian

    #科学基金#

    0

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    2015-03-08 daniustone

    好项目

    0

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    2015-02-28 asukafan

    相关文章有么？？？

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2032932, encodeId=859b203293270, content=<a href='/topic/show?id=0675e48461d' target=_blank style='color:#2F92EE;'>#科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74846, encryptionId=0675e48461d, topicName=科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Tue Apr 28 01:14:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17949, encodeId=1a211e9490f, content=好项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd21607321, createdName=daniustone, createdTime=Sun Mar 08 13:49:00 CST 2015, time=2015-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17210, encodeId=18f71e2108c, content=相关文章有么？？？, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150906/IMG55EC57EDF373F3556.jpg, createdBy=83841615840, createdName=asukafan, createdTime=Sat Feb 28 10:43:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15682, encodeId=cc3915682d4, content=小编评论亮了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 13:44:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337960, encodeId=774e133e9605a, content=<a href='/topic/show?id=a6598626921' target=_blank style='color:#2F92EE;'>#自然科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86269, encryptionId=a6598626921, topicName=自然科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494489, encodeId=8ca514944895a, content=<a href='/topic/show?id=084d9499599' target=_blank style='color:#2F92EE;'>#造血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94995, encryptionId=084d9499599, topicName=造血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caed9138962, createdName=俅侠, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497600, encodeId=3196149e6005d, content=<a href='/topic/show?id=02599201364' target=_blank style='color:#2F92EE;'>#调控机制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92013, encryptionId=02599201364, topicName=调控机制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2bce9348572, createdName=villahu, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512411, encodeId=6f3d15124117c, content=<a href='/topic/show?id=f802e4102cb' target=_blank style='color:#2F92EE;'>#祖细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74102, encryptionId=f802e4102cb, topicName=祖细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18310470858, createdName=12498636m52(暂无昵称), createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617766, encodeId=86d2161e766df, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-16 windmilL1989

    小编评论亮了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2032932, encodeId=859b203293270, content=<a href='/topic/show?id=0675e48461d' target=_blank style='color:#2F92EE;'>#科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74846, encryptionId=0675e48461d, topicName=科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Tue Apr 28 01:14:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17949, encodeId=1a211e9490f, content=好项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd21607321, createdName=daniustone, createdTime=Sun Mar 08 13:49:00 CST 2015, time=2015-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17210, encodeId=18f71e2108c, content=相关文章有么？？？, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150906/IMG55EC57EDF373F3556.jpg, createdBy=83841615840, createdName=asukafan, createdTime=Sat Feb 28 10:43:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15682, encodeId=cc3915682d4, content=小编评论亮了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 13:44:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337960, encodeId=774e133e9605a, content=<a href='/topic/show?id=a6598626921' target=_blank style='color:#2F92EE;'>#自然科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86269, encryptionId=a6598626921, topicName=自然科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494489, encodeId=8ca514944895a, content=<a href='/topic/show?id=084d9499599' target=_blank style='color:#2F92EE;'>#造血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94995, encryptionId=084d9499599, topicName=造血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caed9138962, createdName=俅侠, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497600, encodeId=3196149e6005d, content=<a href='/topic/show?id=02599201364' target=_blank style='color:#2F92EE;'>#调控机制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92013, encryptionId=02599201364, topicName=调控机制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2bce9348572, createdName=villahu, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512411, encodeId=6f3d15124117c, content=<a href='/topic/show?id=f802e4102cb' target=_blank style='color:#2F92EE;'>#祖细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74102, encryptionId=f802e4102cb, topicName=祖细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18310470858, createdName=12498636m52(暂无昵称), createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617766, encodeId=86d2161e766df, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-15 12498b37m72暂无昵称

    #自然科学基金#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2032932, encodeId=859b203293270, content=<a href='/topic/show?id=0675e48461d' target=_blank style='color:#2F92EE;'>#科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74846, encryptionId=0675e48461d, topicName=科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Tue Apr 28 01:14:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17949, encodeId=1a211e9490f, content=好项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd21607321, createdName=daniustone, createdTime=Sun Mar 08 13:49:00 CST 2015, time=2015-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17210, encodeId=18f71e2108c, content=相关文章有么？？？, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150906/IMG55EC57EDF373F3556.jpg, createdBy=83841615840, createdName=asukafan, createdTime=Sat Feb 28 10:43:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15682, encodeId=cc3915682d4, content=小编评论亮了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 13:44:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337960, encodeId=774e133e9605a, content=<a href='/topic/show?id=a6598626921' target=_blank style='color:#2F92EE;'>#自然科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86269, encryptionId=a6598626921, topicName=自然科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494489, encodeId=8ca514944895a, content=<a href='/topic/show?id=084d9499599' target=_blank style='color:#2F92EE;'>#造血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94995, encryptionId=084d9499599, topicName=造血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caed9138962, createdName=俅侠, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497600, encodeId=3196149e6005d, content=<a href='/topic/show?id=02599201364' target=_blank style='color:#2F92EE;'>#调控机制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92013, encryptionId=02599201364, topicName=调控机制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2bce9348572, createdName=villahu, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512411, encodeId=6f3d15124117c, content=<a href='/topic/show?id=f802e4102cb' target=_blank style='color:#2F92EE;'>#祖细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74102, encryptionId=f802e4102cb, topicName=祖细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18310470858, createdName=12498636m52(暂无昵称), createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617766, encodeId=86d2161e766df, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-15 俅侠

    #造血#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2032932, encodeId=859b203293270, content=<a href='/topic/show?id=0675e48461d' target=_blank style='color:#2F92EE;'>#科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74846, encryptionId=0675e48461d, topicName=科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Tue Apr 28 01:14:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17949, encodeId=1a211e9490f, content=好项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd21607321, createdName=daniustone, createdTime=Sun Mar 08 13:49:00 CST 2015, time=2015-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17210, encodeId=18f71e2108c, content=相关文章有么？？？, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150906/IMG55EC57EDF373F3556.jpg, createdBy=83841615840, createdName=asukafan, createdTime=Sat Feb 28 10:43:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15682, encodeId=cc3915682d4, content=小编评论亮了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 13:44:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337960, encodeId=774e133e9605a, content=<a href='/topic/show?id=a6598626921' target=_blank style='color:#2F92EE;'>#自然科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86269, encryptionId=a6598626921, topicName=自然科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494489, encodeId=8ca514944895a, content=<a href='/topic/show?id=084d9499599' target=_blank style='color:#2F92EE;'>#造血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94995, encryptionId=084d9499599, topicName=造血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caed9138962, createdName=俅侠, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497600, encodeId=3196149e6005d, content=<a href='/topic/show?id=02599201364' target=_blank style='color:#2F92EE;'>#调控机制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92013, encryptionId=02599201364, topicName=调控机制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2bce9348572, createdName=villahu, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512411, encodeId=6f3d15124117c, content=<a href='/topic/show?id=f802e4102cb' target=_blank style='color:#2F92EE;'>#祖细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74102, encryptionId=f802e4102cb, topicName=祖细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18310470858, createdName=12498636m52(暂无昵称), createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617766, encodeId=86d2161e766df, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-15 villahu

    #调控机制#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2032932, encodeId=859b203293270, content=<a href='/topic/show?id=0675e48461d' target=_blank style='color:#2F92EE;'>#科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74846, encryptionId=0675e48461d, topicName=科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Tue Apr 28 01:14:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17949, encodeId=1a211e9490f, content=好项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd21607321, createdName=daniustone, createdTime=Sun Mar 08 13:49:00 CST 2015, time=2015-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17210, encodeId=18f71e2108c, content=相关文章有么？？？, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150906/IMG55EC57EDF373F3556.jpg, createdBy=83841615840, createdName=asukafan, createdTime=Sat Feb 28 10:43:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15682, encodeId=cc3915682d4, content=小编评论亮了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 13:44:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337960, encodeId=774e133e9605a, content=<a href='/topic/show?id=a6598626921' target=_blank style='color:#2F92EE;'>#自然科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86269, encryptionId=a6598626921, topicName=自然科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494489, encodeId=8ca514944895a, content=<a href='/topic/show?id=084d9499599' target=_blank style='color:#2F92EE;'>#造血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94995, encryptionId=084d9499599, topicName=造血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caed9138962, createdName=俅侠, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497600, encodeId=3196149e6005d, content=<a href='/topic/show?id=02599201364' target=_blank style='color:#2F92EE;'>#调控机制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92013, encryptionId=02599201364, topicName=调控机制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2bce9348572, createdName=villahu, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512411, encodeId=6f3d15124117c, content=<a href='/topic/show?id=f802e4102cb' target=_blank style='color:#2F92EE;'>#祖细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74102, encryptionId=f802e4102cb, topicName=祖细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18310470858, createdName=12498636m52(暂无昵称), createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617766, encodeId=86d2161e766df, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-15 12498636m52(暂无昵称)

    #祖细胞#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2032932, encodeId=859b203293270, content=<a href='/topic/show?id=0675e48461d' target=_blank style='color:#2F92EE;'>#科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74846, encryptionId=0675e48461d, topicName=科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Tue Apr 28 01:14:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17949, encodeId=1a211e9490f, content=好项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd21607321, createdName=daniustone, createdTime=Sun Mar 08 13:49:00 CST 2015, time=2015-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17210, encodeId=18f71e2108c, content=相关文章有么？？？, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150906/IMG55EC57EDF373F3556.jpg, createdBy=83841615840, createdName=asukafan, createdTime=Sat Feb 28 10:43:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15682, encodeId=cc3915682d4, content=小编评论亮了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 13:44:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337960, encodeId=774e133e9605a, content=<a href='/topic/show?id=a6598626921' target=_blank style='color:#2F92EE;'>#自然科学基金#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86269, encryptionId=a6598626921, topicName=自然科学基金)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494489, encodeId=8ca514944895a, content=<a href='/topic/show?id=084d9499599' target=_blank style='color:#2F92EE;'>#造血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94995, encryptionId=084d9499599, topicName=造血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caed9138962, createdName=俅侠, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497600, encodeId=3196149e6005d, content=<a href='/topic/show?id=02599201364' target=_blank style='color:#2F92EE;'>#调控机制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92013, encryptionId=02599201364, topicName=调控机制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2bce9348572, createdName=villahu, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512411, encodeId=6f3d15124117c, content=<a href='/topic/show?id=f802e4102cb' target=_blank style='color:#2F92EE;'>#祖细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74102, encryptionId=f802e4102cb, topicName=祖细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18310470858, createdName=12498636m52(暂无昵称), createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617766, encodeId=86d2161e766df, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Sun Feb 15 02:14:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-15 12498c32m74暂无昵称

    #生物学#

    0

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