流行病学研究:维生素C、胡萝卜素等抗氧化剂可以降低肺癌风险

2017-03-09 生物谷 生物谷

一项近日发表在Frontiers in Oncology的流行病学研究表明含有高类胡萝卜素和维生素C的饮食也许可以帮助免患肺癌。该研究的作者发现维生素C似乎可以降低经常吸烟男性的肺癌风险,同时beta-胡萝卜素、alpha-胡萝卜素、beta-隐黄质和番茄红素都具有相似的效应。 同时这些氧化剂中的某些物质还和重度吸烟或者不吸烟女性的肺癌风险相


一项近日发表在Frontiers in Oncology的流行病学研究表明含有高类胡萝卜素和维生素C的饮食也许可以帮助免患肺癌。该研究的作者发现维生素C似乎可以降低经常吸烟男性的肺癌风险,同时beta-胡萝卜素、alpha-胡萝卜素、beta-隐黄质和番茄红素都具有相似的效应。

同时这些氧化剂中的某些物质还和重度吸烟或者不吸烟女性的肺癌风险相关。“我们的研究表明维生素C可以保护不吸烟女性免患肺癌。据我们所知,这是此前从未报道过的现象。”该研究第一作者、博士后Martine Shareck这样说道。

这项研究使用了来自肺癌病例对照研究的数据,这是少有的按照吸烟强度探索像维生素C、类胡萝卜素这类抗氧化剂的作用的研究。也是首个考虑吸烟时间及戒烟时间的研究,而这两个参数均是肺癌的关键历史因素。

“对于最常见的3种肺癌亚型,我们发现维生素C、beta-胡萝卜素、allpha-胡萝卜素、beta-隐黄质和番茄红素的高摄入量和人群鳞状细胞癌风险降低有关,而摄入大量beta-胡萝卜素、allpha-胡萝卜素可以降低腺癌的风险。”该研究共同作者、INRS研究所Armand-Frappier研究中心的Marie-élise教授说道,“中到高剂量摄入beta-隐黄质和番茄红素均可以降低小细胞肺癌的风险。”

吸烟是肺癌最重要的危险因素,而肺癌已经成为了全世界癌症相关死亡的最大死因之一。同时日常饮食也可以影响这种癌症的发生。基于这项研究,作者认为通过增加人体食用富含类胡萝卜素和维生素C的蔬菜和水果来降低吸烟和不吸烟人群的肺癌风险应该是合理的。

原文出处:

Martine Shareck et al, Inverse Association between Dietary Intake of Selected Carotenoids and Vitamin C and Risk of Lung Cancer, Frontiers in Oncology (2017). DOI: 10.3389/fonc.2017.00023

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    2017-05-23 sjq027
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    2017-03-25 1e145228m78(暂无匿称)

    学习了谢谢作者分享!

    0

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    2017-03-11 xugumin
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