Clinica Chimica Acta:溶血后血清钾水平恢复的统计模型

2019-11-23 gladiator MedSci原创

血样溶血影响分析前的质量,并可能导致假高钾血症

血样溶血影响分析前的质量,并可能导致假高钾血症。在此,本研究建立了一个统计模型来估计校正后的血清钾(K+)

研究人员分析血清K+H指数,从全血检查(FBE)结果中获得血细胞指数。采用溶血(H)指数、K+和共变异的血细胞指数对139血液标本进行线性回归分析。该模型随后在26个体外物理溶血血清样本上进行了验证。

研究结果显示:最终模型选择H指数、血红蛋白浓度(HGB)、红细胞压积(HCT)作为K+含量的重要预测因子。模型经人工溶血血清样品验证,结果显示溶血净K+增加与预测值之间的相关系数为0.942。预测因子H指数、HCTHB对模型R2的贡献率分别为93.7%3.5%2.8%

研究表明,体外溶血诱导的假高钾血症可由本模型准确预测和修复,并可进行临床应用。

原始出处:

Wei-zheng ZhangDavid J. PriceA statistical model for restoration of serum potassium level disturbed by hemolysis

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1984293, encodeId=2f4d19842939e, content=<a href='/topic/show?id=d6b1894e1c8' target=_blank style='color:#2F92EE;'>#血清钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89471, encryptionId=d6b1894e1c8, topicName=血清钾)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Mon Aug 03 06:24:00 CST 2020, time=2020-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849799, encodeId=533c1849e99ee, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Mon Apr 06 06:24:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1047744, encodeId=0b27104e7441f, content=梅斯里提供了很多疾病的模型计算公式,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Nov 24 00:24:00 CST 2019, time=2019-11-24, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1984293, encodeId=2f4d19842939e, content=<a href='/topic/show?id=d6b1894e1c8' target=_blank style='color:#2F92EE;'>#血清钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89471, encryptionId=d6b1894e1c8, topicName=血清钾)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Mon Aug 03 06:24:00 CST 2020, time=2020-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849799, encodeId=533c1849e99ee, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Mon Apr 06 06:24:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1047744, encodeId=0b27104e7441f, content=梅斯里提供了很多疾病的模型计算公式,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Nov 24 00:24:00 CST 2019, time=2019-11-24, status=1, ipAttribution=)]
    2020-04-06 windight
  3. [GetPortalCommentsPageByObjectIdResponse(id=1984293, encodeId=2f4d19842939e, content=<a href='/topic/show?id=d6b1894e1c8' target=_blank style='color:#2F92EE;'>#血清钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89471, encryptionId=d6b1894e1c8, topicName=血清钾)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Mon Aug 03 06:24:00 CST 2020, time=2020-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849799, encodeId=533c1849e99ee, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Mon Apr 06 06:24:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1047744, encodeId=0b27104e7441f, content=梅斯里提供了很多疾病的模型计算公式,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Nov 24 00:24:00 CST 2019, time=2019-11-24, status=1, ipAttribution=)]
    2019-11-24 CHANGE

    梅斯里提供了很多疾病的模型计算公式,赞一个!

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