Dermatol Surg:皮秒vs.Nd: YAG激光治疗亚洲人表皮和真皮色素病变的效果

2021-09-20 MedSci原创 MedSci原创

亚洲人群良性皮肤色素病变的清除十分困难,由于亚洲人的黑色素细胞反应性强,在激光手术后往往会出现不利的不良反应,包括色素沉着、纹理改变和瘢痕。目前,皮秒激光器在治疗色素性病变方面是否优于Q开关激光器还没

亚洲人群良性皮肤色素病变的清除十分困难,由于亚洲人的黑色素细胞反应性强,在激光手术后往往会出现不利的不良反应,包括色素沉着、纹理改变和瘢痕。目前,皮秒激光器在治疗色素性病变方面是否优于Q开关激光器还没有得到明确的评估。近日,发表于Dermatol Surg的一项随机研究比较了皮秒激光和Q-开关激光在治疗亚洲人的表皮和真皮色素病变方面的疗效和安全性。

研究纳入了8名患有雀斑的受试者和6名获得性双侧太田痣样斑块的受试者。随机分组受试者,一侧面部接受皮秒激光治疗,另一侧用Q-开关激光治疗。在最后一次治疗后的第0、4、12和24周,对色素清除和不良反应进行了主观评估。

 

14名女性患者(平均年龄41岁),皮肤光型为III(1/14,7%)、IV(8/14,57%)和V(5/14,36%)。结果显示,在第4周(p=0.034)、第12周(p=0.039)和第24周(p=0.027),两种激光系统的临床改善情况不同,85.7%的皮秒激光和57.2%的Q-开关激光部位在6个月时有>50%的改善。副作用的发生率和愈合时间没有明显差异,但皮秒激光与较低的治疗不适感明显相关(p = .05)。

综上,该研究结果表明,皮秒激光在治疗亚洲人的色素性病变方面似乎比Q-开关激光更有效、更耐受。

 

原始出处:

 

Chanida Ungaksornpairote, et al., A Prospective, Split-Face, Randomized Study Comparing Picosecond to Q-Switched Nd: YAG Laser for Treatment of Epidermal and Dermal Pigmented Lesions in Asians. Dermatol Surg. 2020 Dec;46(12):1671-1675. doi: 10.1097/DSS.0000000000002486.

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    2022-01-02 hyf028
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    2021-11-07 sunylz
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    2021-09-22 oliver169
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