Sci Rep:传统日本食物梅花具有抗过敏作用

2018-08-16 AlexYang MedSci原创

在日本,日本梅花是一种传统的食物,并展现出了对健康各种有利的作用。有一些证据表明梅花对过敏性疾病同样有一定的抗过敏作用。最近,有研究人员进行了一个代表性的流行病学先导研究来调查梅花的摄入频率与过敏性症状之间的相关性,过敏性症状中包括了鼻炎。研究包括了居住在日本歌山县563名成年人(288名男性和275名女性)。在调整了年龄、当前疾病和药物治疗因素后,研究发现,具有高梅花摄入频率的女性具有过敏症状显

在日本,日本梅花是一种传统的食物,并展现出了对健康各种有利的作用。有一些证据表明梅花对过敏性疾病同样有一定的抗过敏作用。

最近,有研究人员进行了一个代表性的流行病学先导研究来调查梅花的摄入频率与过敏性症状之间的相关性,过敏性症状中包括了鼻炎。研究包括了居住在日本歌山县563名成年人(288名男性和275名女性)。在调整了年龄、当前疾病和药物治疗因素后,研究发现,具有高梅花摄入频率的女性具有过敏症状显著更低的风险比(OR)(OR: 0.49,95%置信区间(CI): 0.25-0.97)。因此,研究人员在免疫球蛋白E(lgE)敏感的小鼠中,调查了梅花对被动性皮肤过敏(PCA)反应的抗过敏作用。动物研究结果阐释了口服梅花提取物能够减弱PCA反应和肥大细胞脱粒作用。进一步的是,RBL-2H3肥大细胞用来鉴定梅花抗过敏化合物。研究发现,能够抑制lgE调节的肥大细胞脱粒作用的梅花化合物包括:香兰素、丁香酸、原儿茶醛、烯醇和对香豆酸。

最后,研究人员指出,他们的结果表明了梅花具有抑制肥大细胞脱粒作用的能力,并且也许与女性过敏症状风险的减少有关。

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    2018-08-18 yhy100201
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    2018-08-16 sunfeifeiyang

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