Arthritis Care Res:强化生活干预可防治肥胖相关的膝关节痛

2015-07-20 沐晴 译 MedSci原创

近来发表在Arthritis Care & Research(关节炎治疗与研究)的一篇研究表明,对于超重的成年糖尿病患者,强化生活方式干预(ILI)可以预防膝关节疼痛。 先前一项糖尿病健康研究(Look AHEAD)表明,在基线水平,糖尿病并不增加膝关节疼痛的风险,但是在肥胖糖尿病患者,膝关节疼痛风险很高。来自纽约特拉华大学的White博士及其同事,从Look AHEAD研究中,

近来发表在Arthritis Care & Research(关节炎治疗与研究)的一篇研究表明,对于超重的成年糖尿病患者,强化生活方式干预(ILI)可以预防膝关节疼痛。

先前一项糖尿病健康研究(Look AHEAD)表明,在基线水平,糖尿病并不增加膝关节疼痛的风险,但是在肥胖糖尿病患者,膝关节疼痛风险很高。来自纽约特拉华大学的White博士及其同事,从Look AHEAD研究中,选择2899名受试者作为亚群进行分析——是否强化生活方式干预,可以预防超重糖尿病患者的膝关节疼痛。

在追踪随访的第一年和第四年,分别对强化生化方式(ILI)或糖尿病教育(DSE)对膝关节疼痛事件的影响进行检测。ILIDSE两组受访者的年龄、性别、BMI大致相似,在基线水平,即随访初,均无膝关节痛病史。在随访第一年,研究者发现与DSE组相比,ILI组膝关节疼痛的发生率降低15%RR 0.85; 95% CI 0.74-0.98)。而在随访的第四年,这种差异下降到5%ILIDSE两组间不存在差异性。

因此,“在肥胖糖尿病人群中,通过饮食和运动方面的强化生活方式干预,可以在短期内预防膝关节疼痛的发生。”研究者认为:“在存在高风险膝关节痛发生人群,如肥胖或者糖尿病合并肥胖者,医疗保健者可以考虑推荐合理的饮食和运动方式阻止膝关节痛发生。”

原始出处:

White DK, Neogi T, Rejeski WJ, et al.Can an Intensive Diet and Exercise Program Prevent Knee Pain Among Overweight Adults at High Risk?. Arthritis Care Res (Hoboken). 2015 Jul;67(7):965-71. doi: 10.1002/acr.22544

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    2015-09-23 zutt
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    2015-07-22 zhaojie88
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