Crit Care:早期和晚期肾替代治疗对心脏手术后急性肾损伤患者死亡率的影响!

2017-06-19 xing.T MedSci原创

由此可见,早期开始RRT治疗可以降低28天的死亡率,尤其是当它在心脏手术后发生AKI的患者发病24小时内。

急性肾损伤是心脏外科手术后常见的并发症,并且会增加患者的死亡率和住院率。近日,危重病医学领域权威杂志Critical Care上发表了一篇荟萃分析文章,研究人员旨在探讨并进行更新的荟萃分析来定性和定量地评估早期肾脏替代治疗(RRT)和死亡率之间的关系。

研究人员检索了中国生物医学文献数据库、Cochrane图书馆、EMbase、全球健康网、Medline和PubMed等数据库。

研究人员确定了十五项研究(五个随机对照试验(RCT),一个前瞻性队列和九个回顾性队列),包括1479名患者被确定并进行详细评估。荟萃分析表明早期开始RRT可以降低28天死亡率(比值比(OR)为0.36;95%可信区间(CI)为0.23-0.57;I2=60%),缩短ICU(重症监护病房)住院时间(LOS)(平均差异(MD)为-2.50;95%CI为-3.53至-1.47;I2=88%)和住院LOS(MD为-0.69;95%CI为-1.13至-0.25;I2=88%),也降低了RRT的持续时间(MD为-1.18;95%CI为-2.26至-0.11;I2=69%),尤其是当心脏手术患者AKI后RRT开始较早,在12小时内(比值比为0.23;95%可信区间为0.08到0.63;I2=73%)在24小时内(比值比为0.52;95%可信区间为0.28至0.95;I2=58%)。

由此可见,早期开始RRT治疗可以降低28天的死亡率,尤其是当它在心脏手术后发生AKI的患者发病24小时内。

原始出处:

Honghong Zou,et al. Early versus late initiation of renal replacement therapy impacts mortality in patients with acute kidney injury post cardiac surgery: a meta-analysis.Critical Care.2017. https://ccforum.biomedcentral.com/articles/10.1186/s13054-017-1707-0

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    2017-06-19 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0

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    2017-06-19 我是谁??

    学习了。。。。。。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1692844, encodeId=914e1692844fb, content=<a href='/topic/show?id=e6d86032ee8' target=_blank style='color:#2F92EE;'>#替代治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60327, encryptionId=e6d86032ee8, topicName=替代治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b79d29305168, createdName=wfang555, createdTime=Mon Oct 02 04:46:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1983517, encodeId=2d4b198351e45, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat Jun 24 09:46:00 CST 2017, time=2017-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397226, encodeId=0616139e22634, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Jun 20 23:46:00 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212871, encodeId=65f32128e1d2, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Jun 19 22:52:13 CST 2017, time=2017-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212692, encodeId=f5642126927f, content=学习了。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo51eheDrP8dFkRicVB5LyaVk2Nc1S87J8nCBgASWQ4rrorsyzzr0UzN8N5bibeqGofE7ZtdT6YNZHEQ/0, createdBy=28d72072417, createdName=我是谁??, createdTime=Mon Jun 19 10:03:54 CST 2017, time=2017-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212670, encodeId=72f42126e088, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon Jun 19 08:52:46 CST 2017, time=2017-06-19, status=1, ipAttribution=)]
    2017-06-19 1771ae4158m

    学习一下很不错

    0

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