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Hypertension：从儿童到成年的血压变化轨迹居然有大作用！

2017-01-19 xing.T MedSci原创

血压变化轨迹
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该研究结果表明，从童年到成年的年轻人期间不同的血压变化轨迹与IMT和LVMI独立相关。该研究首次报道了来自儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。

近日，心血管权威杂志Hypertension上发表一篇研究文章，研究人员旨在明确从童年到成年的年轻人这段时间内血压变化轨迹相似的个体人群，并且明确血压变化轨迹与颈动脉内膜厚度（IMT）和左室质量指数（LVMI）之间的关系。 

该研究有683名参与者从童年到成年的年轻人这段时间内（0-23岁期间）测量血压的次数≤16，而进行IMT、LVMI测量的参与者分别有551名和546名。研究人员使用潜在类别模型，参与者从童年到成年的年轻人根据血压分成3个组，分别为高增长组、中度增长组和低增长组。 

研究人员发现，收缩压的变化轨迹的IMT和LVMI的显著预测因子，收缩压增长速率增加与较高水平的IMT和LVMI相关（P趋势＜0.001）。其他从童年到成年的年轻人血压变化轨迹组较为相似，在童年期（≤18年）3个血压变化轨迹的参与者都进行了血压测量；与低增长组比较，研究人员发现血压高增长组的参与者IMT增厚（P＜0.001）并且LVMI增加（P=0.043）。中度增长组参与者的结果也相似，但在舒张压变化轨迹中并不存在类似结果。 

该研究结果表明，从童年到成年的年轻人期间不同的血压变化轨迹与IMT和LVMI独立相关。该研究首次报道了来自儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。 

原始出处： 

Guang Hao, et al. Blood Pressure Trajectories From Childhood to Young Adulthood Associated With Cardiovascular Risk. Hypertension. 2017. http://hyper.ahajournals.org/content/early/2017/01/16/HYPERTENSIONAHA.116.08312

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    2017-11-10 feather89

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    2017-10-15 ms1467340776200723

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content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-10-18 12498ebem19暂无昵称

    #TENS#

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content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-11-23 FukaiBao

    #变化轨迹#

    0

  5. 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content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-01-21 jambiya

    #Hypertension#

    0

  6. 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content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-01-20 1e1f3a67m99(暂无匿称)

    独特的研究

    0

  7. 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content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-01-20 1ddf0692m34(暂无匿称)

    好东西

    0

  8. 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likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKPeeEwPQq9TMKicgf58mJaQxKhBsHa2jnPrEYVBnZ8QD4tbiaUo3aNqM7EUfOzoPiaEELUb7VRE0HKA/132, createdBy=afcb2012691, createdName=1e1f3a67m99(暂无匿称), createdTime=Fri Jan 20 14:25:18 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171591, encodeId=ffb21e1591e1, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Jan 20 13:54:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171580, encodeId=188c1e1580fb, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-01-20 忠诚向上

    好好学习

    0

  9. 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content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-01-20 1e10c84am36(暂无匿称)

    文章太好了，多读受益

    0

  10. 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content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Jan 20 11:34:31 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171553, encodeId=b9011e1553d1, content=文章太好了，多读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jan 20 10:18:13 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171542, encodeId=ffc81e154284, content=儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Fri Jan 20 10:01:47 CST 2017, time=2017-01-20, status=1, ipAttribution=)]
    2017-01-20 inter158

    儿童期的收缩压变化轨迹与青年期亚临床心血管疾病风险之间的相关性，表明从儿童时期开始监测血压的变化轨迹可能有助于识别早期心血管疾病高危人群。

    0

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