J Hypertens:青少年高血压前期与未来终末期肾病风险有何关系?

2017-05-21 xing.T MedSci原创

由此可见,无症状、健康的高血压前期青少年随后发生ESRD的风险增加2%,相比于最佳血压的青少年。

成年期持续性高血压是终末期肾病(ESRD)的主要原因。在高血压前期范围较低的血压值是否也与将来ESRD的发生存在相关性尚不清楚。甚至不清楚青春期发生高血压前期的潜在风险。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,为了解决这个问题,研究人员评估了16-19岁青年人血压测量值在高血压前期范围内是否可以预测成人ESRD。

在这项全国人口为基础的队列研究中,在1977年至2013年期间在服兵役之前对2194635名16-19岁青少年评估医疗健康的 医疗数据与以色列ESRD登记中心相互链接。记录了ESRD的发生病例,并使用了生存模型。

在35007506人次每年的随访中(平均随访时间为16.8年),有690例ESRD病例,总发病率为1.97例每100000人每年。升高的血压读数在高血压前期范围的受检者(血压在第九十和第九十五百分位范围或120-139/80-89mmHg之间的受检者)发生ESRD有所增加,其风险比为1.32(95%可信区间为1.11-1.58),调整了出生年份、受检年龄、性别、体重指数、教育程度、社会经济地位和国家。高血压(血压高于第九十五百分位数,或大于140/90mmHg)与ESRD发生相关的风险比为1.44(95%可信区间为1.17-1.79)。样条模型显示SBP值低94 mmHg时,其风险最低。

由此可见,无症状、健康的高血压前期青少年随后发生ESRD的风险增加2%,相比于最佳血压的青少年。

原始出处:


Leiba, Adi.et al. Prehypertension among 2.19 million adolescents and future risk for end-stage renal disease.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/2017/06000/Prehypertension_among_2_19_million_adolescents_and.23.aspx

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  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 22 13:50:01 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201007, encodeId=942320100ecc, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Mon May 22 00:31:12 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200931, encodeId=c7f6200931f1, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sun May 21 18:38:02 CST 2017, time=2017-05-21, status=1, ipAttribution=)]
    2017-05-23 1e1b8538m79(暂无匿称)

    这个是个不错的文章,受教了

    0

  6. 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createdName=dhzzm, createdTime=Sun May 21 18:38:02 CST 2017, time=2017-05-21, status=1, ipAttribution=)]
  7. 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  8. 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topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Fri Jun 09 23:05:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201705, encodeId=db7d201e05c0, content=这个是个不错的文章,受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue May 23 17:28:41 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490843, encodeId=ca5c14908434f, content=<a href='/topic/show?id=ead91026621c' target=_blank style='color:#2F92EE;'>#高血压前期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102662, encryptionId=ead91026621c, topicName=高血压前期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1448837648, createdName=kord1985, createdTime=Tue May 23 04:05:00 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1476354, encodeId=a2e414e63549c, content=<a href='/topic/show?id=eb69e81665d' target=_blank style='color:#2F92EE;'>#终末期肾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78166, encryptionId=eb69e81665d, topicName=终末期肾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fb27278676, createdName=zengjiayao, createdTime=Tue May 23 04:05:00 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201249, encodeId=3f8a2012490a, content=不错的文章,可以看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 22 13:50:01 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201007, encodeId=942320100ecc, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Mon May 22 00:31:12 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200931, encodeId=c7f6200931f1, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sun May 21 18:38:02 CST 2017, time=2017-05-21, status=1, ipAttribution=)]
    2017-05-22 1e1b8538m79(暂无匿称)

    不错的文章,可以看看

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1693454, encodeId=2e93169345419, content=<a href='/topic/show?id=7e2de81588c' target=_blank style='color:#2F92EE;'>#终末期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78158, encryptionId=7e2de81588c, topicName=终末期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1f6429431807, createdName=anminleiryan, createdTime=Tue Oct 10 18:05:00 CST 2017, time=2017-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726422, encodeId=c57a1e264226d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Fri Jun 09 23:05:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201705, encodeId=db7d201e05c0, content=这个是个不错的文章,受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue May 23 17:28:41 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490843, encodeId=ca5c14908434f, content=<a href='/topic/show?id=ead91026621c' target=_blank style='color:#2F92EE;'>#高血压前期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102662, encryptionId=ead91026621c, topicName=高血压前期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1448837648, createdName=kord1985, createdTime=Tue May 23 04:05:00 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1476354, encodeId=a2e414e63549c, content=<a href='/topic/show?id=eb69e81665d' target=_blank style='color:#2F92EE;'>#终末期肾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78166, encryptionId=eb69e81665d, topicName=终末期肾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fb27278676, createdName=zengjiayao, createdTime=Tue May 23 04:05:00 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201249, encodeId=3f8a2012490a, content=不错的文章,可以看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 22 13:50:01 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201007, encodeId=942320100ecc, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Mon May 22 00:31:12 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200931, encodeId=c7f6200931f1, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sun May 21 18:38:02 CST 2017, time=2017-05-21, status=1, ipAttribution=)]
    2017-05-22 130****4638

    学习了谢谢分享。

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 22 13:50:01 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201007, encodeId=942320100ecc, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Mon May 22 00:31:12 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200931, encodeId=c7f6200931f1, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sun May 21 18:38:02 CST 2017, time=2017-05-21, status=1, ipAttribution=)]
    2017-05-21 dhzzm

    学习了分享了

    0

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