JAMA Intern Med:心肺功能可预测远期心血管疾病

2017-11-03 小闪 医学论坛网

发表于《美国医学会杂志·内科学》一项研究表明,青年期的心肺功能水平可预测远期的心脏功能情况。


发表于《美国医学会杂志·内科学》一项研究表明,青年期的心肺功能水平可预测远期的心脏功能情况。
    
青年期冠状动脉风险发展(CARDIA)研究的最新结果表明,如果一个不大于30岁的成年人在基础平板运动实验中得分较高,那么25年后他的左室质量指数会相对较低,而二维整体纵向应变力(一种亚临床功能紊乱指标)则相对更好。
    
此外,研究者指出如果研究对象在基础平板实验中能多坚持一分钟,那么他死亡的危险性下降15%,患心血管病的危险性下降12%。在其7年后参加的随访测试中,坚持的时间每减少一分钟,心血管病的患病风险升高20%,死亡率升高21%。而心肺功能水平和冠脉钙化程度无显著关联。
    
研究者认为规律的运动可以提升年轻人的心肺功能水平,这可能在促进心血管健康和阻止早期心血管病发展中起到重要的作用。
     
随后的一篇评论认为,该项研究的亮点在于指出了心肺功能作为一项青年群体中心血管病危险因素的重要性。青壮年心肺功能发挥保护作用的生理学机制与其对动脉粥样硬化斑块发展的抑制无关,而是与其对心肌结构与功能的某种未知作用有关。心肺功能与冠状动脉钙化评分无关可能是由该研究中研究对象发生心血管事件率或死亡率太低导致的。
    
研究人员称,在这项大型的双人种队列,心肺功能与心血管病事件以及全因素死亡率密切相关,而不受心脏代谢和心血管疾病危险因素的干扰。因此,心肺功能是心血管远期风险的一种可变的预测指标。
      
原始出处:

Shah RV, Murthy VL, Colangelo LA,et al.Association of Fitness in Young Adulthood With Survival and Cardiovascular Risk: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.JAMA Intern Med. 2016 Jan;176(1):87-95. doi: 10.1001/jamainternmed.2015.6309.

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    2018-03-07 aids222
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    2017-11-22 微分

    非常好的文章.学习了

    0

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    2017-11-08 天涯183

    非常好的文章.学习了

    0

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    2017-11-03 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

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    2017-11-03 天涯183

    非常好的文章.学习了

    0

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臭氧暴露与心血管疾病死亡率有关,但其潜在的生物学机制尚不清楚。

JAMA intern Med:健康成人中臭氧暴露和心肺病理生理机制间的关联

暴露于臭氧中会影响心血管病死亡发生率,但是其中暗含的生物学机制却并不清楚。本文旨在探究臭氧暴露和心肺病理生理机制间的关联。从2014年12月1日到2015年1月31日期间对中国长沙89名健康成年校园工作人员进行观察研究。这种独特的拟实验性设计能够更好的表征暴露于空气污染环境中产生的效果,因为实验者的大部分时间都花在室内环境中。全程监测室内外臭氧浓度以及一氧化碳污染物颗粒,二氧化氮,二氧化硫情况。结

Stroke:中年期心肺功能越好,老年时卒中风险越低

近期发表在Stroke的研究表明,45-50岁具有高心肺适能的人群,其65岁后的卒中风险最高可下降37%,并且独立于其他传统的卒中危险因素。德克萨斯大学西南医学中心的Ambarish Pandey博士对1999-2009年纳入的19815名基线年龄在45到50年人群(男性占79%,白人占90%)进行了研究。该研究测量了参与者跑步机上的心肺运动能力,根据心肺能力的高、中、低水平进行分层,并对年龄和性

孩子心肺功能令人堪忧 远不及父辈当年

据法国《费加罗报》网站报道,位于美国达拉斯(德克萨斯州南部)的美国心脏协会在研究发表会上称,如今世界上多数孩子的心肺功能令人堪忧,而他们的父辈在处于他们这一年龄段时,心肺功能相对好一些。该发表会评估,当这一代的孩子们长大成人时,心肺功能问题将成为影响他们整体健康水准的一大代表性问题。 南澳大利亚大学公共卫生学院的院长,同时也是这次研究发表会的主要研究人员之一的格兰特·

JACC:在中国,室内空气净化对心肺功能好处多

背景:室内暴露于细颗粒物(PM2.5)从室外的来源是一个主要的健康问题,特别是在像中国这样的高污染发展中国家。很少有研究评估这些地区室内空气净化的效果对心肺健康的改善。    目的:本研究旨在评估一个短期的室内空气净化器干预措施是否提高心肺健康。    方法:2014年研究人员在中国上海对35位健康大学生进行随机、双盲、交叉试验。这些学生

JAMA Oncology:锻炼好心肺,防癌又长寿

心肺功能指心脏供血和肺吸氧的能力。即包括心血管系统和呼吸系统。两者协作作用是吸入氧气并运送到身体各个器官,以便为各个器官提供养分和能量。心肺功能良好,也反应身体主要机能都可健康运作,从而可推断出患慢性疾病如心血管病、内分泌系统疾病、呼吸系统疾病的机会较低。根据最新在线发表在JAMA Oncology杂志上的一项研究结果,拥有高健康水平中年男性的肺癌和结直肠癌的风险下降,但非前列腺癌,而更高的健康水