Am J Rhinol Allergy:非过敏性鼻炎患者的临床特性区分

2019-05-23 AlexYang MedSci原创

并不是所有的鼻炎患者均受免疫球蛋白E(lgE)调控的炎症过程影响。由于皮刺和血清过敏原评估受限,因而不能对局部过敏性鼻炎(LAR)进行确诊。因此,具有阴性系统性过敏评估的患者其实包括了非过敏性鼻炎患者(NAR)和LAR患者。最近,有研究人员确定了NAR患者的临床特性。研究是一个代表性的研究,包括了154名参与者(平均年龄为41.79±14.78岁,37.7%的为女性 )。与AR患者相比,NAR患者

并不是所有的鼻炎患者均受免疫球蛋白E(lgE)调控的炎症过程影响。由于皮刺和血清过敏原评估受限,因而不能对局部过敏性鼻炎(LAR)进行确诊。因此,具有阴性系统性过敏评估的患者其实包括了非过敏性鼻炎患者(NAR)和LAR患者。最近,有研究人员确定了NAR患者的临床特性。

研究是一个代表性的研究,包括了154名参与者(平均年龄为41.79±14.78岁,37.7%的为女性 )。与AR患者相比,NAR患者(11.7%)年龄更大(49.33±15.99 vs 40.78±14.38岁, P=0.02),具有更少的自我报道的哮喘(5.6% vs 36.3%, P<0.01)和屋尘螨激发的过敏(38.9 vs 65.2%, P=0.03)。另外,CII得分在NAR和AR患者中相似(31.06±28.88 vs 35.49±24.70, P=0.61)。

最后,研究人员指出,那些年龄更大,没有哮喘和没有吸入过敏激发的参与者更可能是NAR患者。环境激发并不是NAR的区分特性。这些结果也许可以作为鉴定鼻炎患者的指导。

原始出处:

Hamizan AW, Azer M, Alvarado R et al. The Distinguishing Clinical Features of Nonallergic Rhinitis Patients. Am J Rhinol Allergy. 20 May 2019

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    2019-05-25 膀胱癌

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