PLoS ONE :膳食豆制品或异黄酮摄入可降低患结直肠癌的风险

2015-11-23 MedSci MedSci原创

总豆制品或膳食异黄酮摄入量较高与整体结直肠癌的风险降低有关,尤其能降低受试者患远端结肠癌或直肠癌的风险。

韩国国家癌症中心分子流行病学部门Jeongseon Kim和同事进行一个韩国病例对照研究分析异黄酮和豆制品摄入量与结肠直肠癌的风险。研究结果2015年11月17日在PLoS ONE 在线发表。

目的:这项病例对照研究旨在评估膳食豆制品和异黄酮摄入量与结直肠癌风险之间的关系。

方法:研究共纳入在韩国国家癌症中心招募的901例结直肠癌患者和2669例对照组患者。使用半定量食物频率问卷评估受试者日常饮食习惯,从五个豆制品项目中估计异黄酮摄入量。

结果:总豆制品、豆类和豆芽的高摄入量与结直肠癌的风险降低有关,总豆制品的摄入量数与结直肠癌的风险升高有关。相比之下,豆瓣酱的摄入量较高与男性患直肠癌的风险升高有关。

摄入异黄酮最高的患者组与其他受试者相比显示结肠直肠癌的风险降低,男性受试者(OR 0.67,95%CI 0.51-0.89)和女性受试者(OR 0.65,95%CI0.43-0.99)。摄入异黄酮量最高的组显示男性受试者患远端结肠癌和女性受试者患直肠癌的风险均降低。绝经后的妇女中豆制品摄入量与结直肠癌风险之间的关系比绝经前女性中更加突出。

结论:总豆制品或膳食异黄酮摄入量较高与整体结直肠癌的风险降低有关,尤其能降低受试者患远端结肠癌或直肠癌的风险。

原始出处:

Shin A, Lee J, Lee J, et al. Isoflavone and Soyfood Intake and Colorectal Cancer Risk: A Case-Control Study in Korea. PLoS ONE 10(11): e0143228.


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    2017-08-12 随梦飞扬

    ,豆瓣酱的摄入量较高与男性患直肠癌的风险升高有关。

    0

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    2016-12-14 1e137bdcm70(暂无匿称)

    多吃豆制品,以后多吃豆制品

    0

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  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102860, encodeId=52b310286053, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1632208, encodeId=95961632208bc, content=<a href='/topic/show?id=e15649842f0' target=_blank style='color:#2F92EE;'>#异黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49842, encryptionId=e15649842f0, topicName=异黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d821868388, createdName=isabellayj, createdTime=Fri Jan 22 02:39:00 CST 2016, time=2016-01-22, status=1, ipAttribution=)]
    2016-09-13 doctorJiangchao

    继续学习

    0

  5. 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content=<a href='/topic/show?id=e15649842f0' target=_blank style='color:#2F92EE;'>#异黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49842, encryptionId=e15649842f0, topicName=异黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d821868388, createdName=isabellayj, createdTime=Fri Jan 22 02:39:00 CST 2016, time=2016-01-22, status=1, ipAttribution=)]
    2016-09-13 doctorJiangchao

    继续关注

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102860, encodeId=52b310286053, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1632208, encodeId=95961632208bc, content=<a href='/topic/show?id=e15649842f0' target=_blank style='color:#2F92EE;'>#异黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49842, encryptionId=e15649842f0, topicName=异黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d821868388, createdName=isabellayj, createdTime=Fri Jan 22 02:39:00 CST 2016, time=2016-01-22, status=1, ipAttribution=)]
    2016-09-10 医路开来

    多吃黄豆,,

    0

  7. 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createdName=doctorJiangchao, createdTime=Tue Sep 13 11:43:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125000, encodeId=8b1b12500064, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:43:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118935, encodeId=2ab9118935d3, content=多吃黄豆,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Sat Sep 10 11:23:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118936, encodeId=36b7118936df, content=学习啦,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Sat Sep 10 11:23:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102861, encodeId=313a102861d7, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102860, encodeId=52b310286053, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1632208, encodeId=95961632208bc, content=<a href='/topic/show?id=e15649842f0' target=_blank style='color:#2F92EE;'>#异黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49842, encryptionId=e15649842f0, topicName=异黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d821868388, createdName=isabellayj, createdTime=Fri Jan 22 02:39:00 CST 2016, time=2016-01-22, status=1, ipAttribution=)]
    2016-09-10 医路开来

    学习啦,,

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=232658, encodeId=e97923265845, content=,豆瓣酱的摄入量较高与男性患直肠癌的风险升高有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Sat Aug 12 00:32:23 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162840, encodeId=2e191628405b, content=多吃豆制品,以后多吃豆制品, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82351961337, createdName=1e137bdcm70(暂无匿称), createdTime=Wed Dec 14 22:01:52 CST 2016, time=2016-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789742, encodeId=af801e89742d5, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Sep 04 04:39:00 CST 2016, time=2016-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124999, encodeId=bfc412499937, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:43:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125000, encodeId=8b1b12500064, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:43:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118935, encodeId=2ab9118935d3, content=多吃黄豆,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Sat Sep 10 11:23:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118936, encodeId=36b7118936df, content=学习啦,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Sat Sep 10 11:23:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102861, encodeId=313a102861d7, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102860, encodeId=52b310286053, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1632208, encodeId=95961632208bc, content=<a href='/topic/show?id=e15649842f0' target=_blank style='color:#2F92EE;'>#异黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49842, encryptionId=e15649842f0, topicName=异黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d821868388, createdName=isabellayj, createdTime=Fri Jan 22 02:39:00 CST 2016, time=2016-01-22, status=1, ipAttribution=)]
    2016-08-24 doctorJiangchao

    继续关注

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102860, encodeId=52b310286053, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Aug 24 10:16:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1632208, encodeId=95961632208bc, content=<a href='/topic/show?id=e15649842f0' target=_blank style='color:#2F92EE;'>#异黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49842, encryptionId=e15649842f0, topicName=异黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d821868388, createdName=isabellayj, createdTime=Fri Jan 22 02:39:00 CST 2016, time=2016-01-22, status=1, ipAttribution=)]
    2016-08-24 doctorJiangchao

    继续学习

    0

  10. 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