J Endod:口腔内感觉的变化影响罹患有症状不可逆牙髓炎患者的牙髓敏感性测试

2020-05-05 lishiting MedSci原创

这篇病例对照研究的目的是为了比较临床诊断为有症状不可逆牙髓炎患者(n = 33)和健康个体(n = 33)之间三叉神经自体敏感性的差异,以此评估有症状不可逆牙髓炎自体感觉的分层对牙髓敏感性测试的影响。

这篇病例对照研究的目的是为了比较临床诊断为有症状不可逆牙髓炎患者(n = 33)和健康个体(n = 33)之间三叉神经自体敏感性的差异,以此评估有症状不可逆牙髓炎自体感觉的分层对牙髓敏感性测试的影响。

研究采用一套标准的敏感性定性评估系统检测触、冷和针刺对口内和口外的敏感性变化。采取冷刺激(refrigerant spray)引起的牙齿疼痛程度(0-100, numeric rating scale)和持续时间(seconds)分别应用于未受影响和受影响的牙齿以及上颌左右侧的前磨牙(controls);采用z score transformation, analysis of variance (ANOVA)和chi-square检验对数据进行统计学评估(P = .050)。

结果显示,罹患不可逆牙髓炎的患者发生口内超敏反应的频率要明显高于健康个体(分别为58%和33%; P < .05)。此外,与对照组相比,罹患不可逆牙髓炎的患者在牙髓敏感性测试后的疼痛程度(ANOVA main effects, F = 37.10, P < .05, partial η2 = 0.37)和持续时间(ANOVA main effects F = 23.3, P < .05, partial η2 = 0.27)的z得分更高。然而,考虑到存在口内超敏反应的亚组分析表明,大多数罹患有症状不可逆牙髓炎的患者疼痛持续,同时也存在口内的超敏反应(Tukey test, P < .05),但是在罹患不可逆牙髓炎且无口内超敏反应的患者与健康个体之间无显著性差异(Tukey test, P > .05)。

结论:QualST能够检测罹患有症状不可逆牙髓炎患者的口内改变,它有助于将患者分为不同亚组。因此,对于相邻组织的自体感觉评估可以为牙髓疾病的诊断提供微调。

原始出处

Yuri M Costa, Paulo Roberto J de Souza, et al. Intraoral Somatosensory Alterations Impact Pulp Sensibility Testing in Patients With Symptomatic Irreversible Pulpitis. J Endod., 2020 Apr 24;S0099-2399(20)30193-X. doi: 10.1016/j.joen.2020.03.012.

 

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    2020-05-18 jxrzshh
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