JAMA Cardiol:院外心脏骤停患者的10年生存率

2022-05-07 Nebula MedSci原创

院外心脏骤停后住院治疗活着出院后的10年长期生存率在62%至64%之间

尽管在过去几十年中,院前和院内护理都取得了重要进展,但院外心脏骤停 (OHCA) 仍然是居民死亡的主要原因之一。OHCA后住院患者的生存率只有50%-60%,而OHCA存活12个月以上的长期生存数据仍很少。

本研究旨在调查因院外心脏骤停住院治疗后活着出院的成人患者的长期生存率。

研究人员检索了EMBASE和MEDLINE数据库从建立到2021年3月25日期间收录的相关数据,纳入了报道OHCA后长期生存情况的临床研究。使用迭代算法从Kaplan-Meier曲线重构患者数据,然后合并生成生存曲线。主要终点是心脏骤停后活着出院或OHCA后30天后的长期生存率(>12个月)。


院外心脏骤停患者的15年生存率

筛查了15347篇报告,其中21篇(包含11800位患者)被纳入了基于Kaplan-Meier的荟萃分析,33篇 (包含16933位患者) 被纳入了汇总数据荟萃分析。在基于Kaplan-Meier的分析中,院外心脏骤停患者的中位生存时间为5.0年(范围 2.3-7.9年)。估计的3年生存率为82.8%,5年生存率为63.9%,10年生存率为63.9%,15年生存率为57.5%。


可 vs 不可电击复律心律患者的生存率

与不可电击复律心律患者相比,可电击复律心律患者长期死亡风险较低(风险比 0.30,p<0.001)。不同的分析,包括汇总数据的元分析,均证实了上述结果。

综上所述,在这项全面的系统综述和荟萃分析中,院外心脏骤停后住院治疗活着出院后的10年长期生存率在62%至64%之间

原始出处:

Amacher SA, Bohren C, Blatter R, et al. Long-term Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-analysis. JAMA Cardiol. Published online May 04, 2022. doi:10.1001/jamacardio.2022.0795

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    2022-05-07 肿瘤克星

    JAMA上文章都是顶级的,谢谢梅斯及时上新

    0

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