AP&T: 无麸质饮食的乳糜泻患者会增加患非酒精性脂肪性肝病的风险

2018-08-30 MedSci MedSci原创

目前有文献报到无谷蛋白饮食(GFD)与患者常出现代谢综合征有关。非酒精性脂肪性肝病(NAFLD)是代谢综合征的一项重要表现。乳糜泻患者(CD)患NAFLD的风险仍有待进一步研究。本项研究旨在评估用GFD治疗的CD患者中NAFLD的患病率和相对风险的变化。

背景
目前有文献报到无谷蛋白饮食(GFD)与患者常出现代谢综合征有关。非酒精性脂肪性肝病(NAFLD)是代谢综合征的一项重要表现。乳糜泻患者(CD)患NAFLD的风险仍有待进一步研究。本项研究旨在评估用GFD治疗的CD患者中NAFLD的患病率和相对风险的变化。

方法
本项研究是一项病例对照研究,研究人员按照1:1的比例匹配患者的人口统计学特征(年龄和性别)和代谢危险因素(超重,糖尿病,总胆固醇和甘油三酯)从而将患有CD的患者与健康对照组随机分组。。

结果
本项研究总共比较了202名CD患者和202名健康对照人群。CD和对照组的NAFLD原始患病率分别为34.7%和21.8%(P= 0.006)。二元logistic回归分析证实CD组NAFLD风险是显着增加的(OR= 2.90,95%置信区间:1.64-5.15,P<0.001)。此外,NAFLD的相对风险在非超重CD患者中显着更高(OR= 5.71,95%置信区间:2.30-14.19,P<0.001)。

结论
有超过三分之一的接受GFD饮食的CD患者同时患有NAFLD,与一般人群相比,患NAFLD的风险增加了三倍。因此针对患者的体质提供的饮食建议可以帮助患有NAFLD的CD患者实现合适的营养摄入,同时降低长期肝脏相关事件的风险。

原始出处:

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (8)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
    2018-12-31 qjddjq
  2. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1810096, encodeId=e46e181009633, content=<a href='/topic/show?id=70f484349b5' target=_blank style='color:#2F92EE;'>#脂肪性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84349, encryptionId=70f484349b5, topicName=脂肪性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Mon Dec 31 23:25:00 CST 2018, time=2018-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676427, encodeId=dfcb16e6427bf, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d18c27357544, createdName=Tommy1958, createdTime=Tue Mar 19 19:25:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1654015, encodeId=7c9316540153f, content=<a href='/topic/show?id=1e1584351b2' target=_blank style='color:#2F92EE;'>#脂肪性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84351, encryptionId=1e1584351b2, topicName=脂肪性肝病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46224431741, createdName=wwzzly, createdTime=Fri Mar 29 14:25:00 CST 2019, time=2019-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940513, encodeId=04621940513aa, content=<a href='/topic/show?id=d10910301364' target=_blank style='color:#2F92EE;'>#麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103013, encryptionId=d10910301364, topicName=麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Thu Nov 29 20:25:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1736344, encodeId=80551e36344d2, content=<a href='/topic/show?id=c9f35918e55' target=_blank style='color:#2F92EE;'>#无麸质饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59187, encryptionId=c9f35918e55, topicName=无麸质饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=923c34148027, createdName=kkunny, createdTime=Fri Jun 28 17:25:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1673424, encodeId=072916e3424bc, content=<a href='/topic/show?id=757b954e922' target=_blank style='color:#2F92EE;'>#酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95479, encryptionId=757b954e922, topicName=酒精性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=398f26933958, createdName=huiwelcome, createdTime=Thu Nov 22 22:25:00 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556663, encodeId=0d821556663aa, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Sat Sep 01 07:25:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341909, encodeId=2d07341909ba, content=即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 31 07:10:01 CST 2018, time=2018-08-31, status=1, ipAttribution=)]
    2018-08-31 太阳系小猪

    即使是乳糜泻也不能小觑,要认真对待,因为会影响长期预后

    0

相关资讯

J Periodontol: 拉美裔中牙周炎和氨基转移酶升高的关系

西班牙裔/拉丁裔中非酒精性脂肪肝(NAFLD)患病率高于其他种族/民族,并且西班牙裔/拉丁裔组间有差异。实验动物和人体研究证明牙周炎和NAFLD之间存在关联,而西班牙裔/拉美裔中尚未报道。这项研究检查了牙周炎可能是西班牙裔/拉美裔中NAFLD的一种新的危险因素。

Liver Int:PPARalpha/gamma激活剂—saroglitazar可改善NASH小鼠的肝脏功能和组织病理水平

Saroglitazar,一种具有PPARalpha/gamma活性的激动剂,可改善NASH疾病。与单纯的PPARalpha激动剂-非诺贝特和PPARgamma激动剂-吡格列酮相比,saroglitazar的效果更好。

Gut:miRNA-132通过协同多靶点抑制,促进肝脂肪变性和高脂血症

研究发现,miR-132是肝脏脂质稳态的关键调控因子,通过抑制多个靶点和累积协同效应,以环境依赖性的方式发挥作用。这表明降低miR-132水平可能治疗肝脂肪变性。

Hepatology:非酒精性脂肪性肝病和非酒精性脂肪性肝炎目前和未来的治疗方案

在未来的5年里,其中一些方案有望为NASH/NAFLD患者提供新的治疗方案。

Diabetes Care:曲格列嗪对2型糖尿病和非酒精性脂肪肝患者肝脏脂肪含量的影响!

由此可见,在2型糖尿病的标准治疗中加入曲格列嗪可以显著降低2型糖尿病和NAFLD患者肝脏脂肪含量,并改善ALT水平。

Liver Int:乙型肝炎病毒感染和非酒精性脂肪肝(NAFLD)风险:基于人群的队列研究

在中国CHB患者中,代谢因素对NAFLD的存在起着重要作用。然而,病毒复制因子与NAFLD没有关系,除了并发2型糖尿病患者。