PD-L1测试在使用内核超声引导针吸入(EBUS-TBNA)中获得的大部分标本中是否可行?

2021-08-19 MedSci原创 MedSci原创

PD-L1测试在使用内核超声引导针吸入(EBUS-TBNA)中获得的大部分标本中是否可行-C-TBNA和EBUS-TBNA的应用_问题1.

《梅斯直播课——支气管镜基本诊疗术及其临床应用

回答问题1:PD-L1测试在使用内核超声引导针吸入(EBUS-TBNA)中获得的大部分标本中是否可行?

 

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    2022-03-16 cy0324
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    2021-08-21 smartjoy
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    2021-08-19 145cf07em96暂无昵称

    学习了

    0

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Chest:EBUS-TBNA与切除肺癌标本之间PD-L1免疫组化染色的比较

EBUS-TBNA的PD-L1阈值≥1%与切除肿瘤标本有强相关性。当PD-L1≥50%时,与切除肿瘤相比,EBUS-TBNA标本的敏感性和PPV显著降低。

J Thor Oncol:超声引导针吸活检术能安全有效地诊断老年肺癌

近日,来自曼彻斯特大学的研究人员通过研究发现,对肺癌患者进行组织取样诊断检测或许仅在老年患者个体中是安全的,这就呼吁医生们需要开发一种更为准确安全的诊断技术,来保证患者的安全,当然这为医生们选择合适的疗法治疗肺癌患者也具有一定的价值,相关研究刊登于国际杂志Journal of Thoracic Oncology上。肺癌患者中有一半患者都是在70多岁时被诊断出了癌症,但是有研究却表明这些老年患者并不

Ann Thorac Surg:上海胸科医院韩宝惠等发现EBUS-TBNA对可疑胸内结核有很高诊断价值

支气管内超声引导下经支气管针吸活检(EBUS-TBNA)是一种微创操作,其对纵隔及肺门淋巴结的诊断评估具有很高的敏感性,但它在诊断胸内结核病(TB)方面的作用尚未明确。为此,来自上海交通大学附属上海市胸科医院内镜中心和肺内科的韩宝惠及其同事进行了一项研究,研究结果发表于2013年9月12日出版的《胸外科年鉴》(Ann Thorac Surg)杂志上。研究结果显示:EBUS-TBNA对于可疑的胸内结

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肺鳞癌耐药,ALK消失,病理转变,检出PD-L1高表达用免疫治疗达临床完全缓解!

该病例强调了ALK-TKI对ALK阳性LSCC患者的潜在价值。对第二代TKI的耐药性可能会导致ALK阴性和组织学转化,这凸显了TKI耐药后重复活检以做出正确治疗决策的必要性。

PD-1 vs PD-L1抑制剂:差异何在?揭秘免疫疗法新篇章!

PD-1抑制剂和PD-L1抑制剂在结构上存在差异,主要体现在它们的抗体分类、结合区域、给药前后构象变化以及ADCC效应等方面。

总生存率高达57.3%!北肿季加孚:双抗治胃癌,可带来18个月生存获益 | AACR 2024

研究显示,与安慰剂+化疗相比,卡度尼利联合化疗可显著改善晚期G/GEJ腺癌患者的总生存期和无进展生存期 ,且安全性可控。

陆军军医大学最新《自然·通讯》:靶向递送Fc融合PD-L1,有效治疗急性和慢性结肠炎

PD-L1-Fc修饰的纳米颗粒可以为IBD的靶向治疗提供有效和安全的策略。

Skin research and technology: PD-L1在尖锐湿疣中的表达及意义

HPV感染可上调尖锐湿疣角质形成细胞PD-L1的表达,并参与局部T细胞功能的抑制。

总生存期相差72%,哪些癌症患者能从免疫治疗联合化疗获益多、获益少?

对于肺癌的不同亚型,如果PD-L1表达的水平不同,患者使用化疗联合免疫治疗的效果差别大吗?今天癌度就给大家编译一篇最新的文献,希望对大家有所帮助。