微创经皮肾穿刺联合钬激光治疗幼儿复杂肾结石1例

2017-08-25 那彦群, 陈山 泌尿外科疑难病例讨论精选

小儿尿路结石发病率不高,但多与代谢异常、尿路畸形和感染有关。本文报告了1例“微创经皮肾穿刺联合钬激光治疗幼儿复杂肾结石”病例。

小儿尿路结石发病率不高,但多与代谢异常、尿路畸形和感染有关。本文报告了1例“微创经皮肾穿刺联合钬激光治疗幼儿复杂肾结石”病例。

【病例资料】

患儿男性,18个月。

主诉:间断全程肉眼血尿3个月。

现病史:患儿,男,18个月,河北籍。患儿于2008年2月无明显诱因间断出现全程肉眼血尿,无发热。在当地医院经腹平片和B超显示:左侧肾盂输尿管交界处有一约1.6cm×1.0cm的铸型结石,左肾盂积水,左肾下盏可见多个直径约0.4cm的结石,于2008年5月至我院就诊。既往体健,32周早产儿,母乳喂养至4个月断奶,奶粉喂养并添加辅食,饮食可。

【体格检查】

一般查体及专科查体均未见明显异常。

【辅助检查】

实验室检查:肌酐:56μmol/L;尿酸:204μmol/L;血钙:2.40mmol/L;血磷:.75mmol/L;甲状旁腺激素正常;尿常规示红细胞(3+),白细胞(+)。

影像学检查:B超显示左侧肾盂输尿管交界处有一约1.6cm×1.0cm的结石,左肾盂积水,左肾下盏可见直径约0.4cm的结石。

【术前诊断

左肾多发结石

【治疗方案】

采用微造瘘的经皮肾镜碎石术。

术中所见:应用气管插管全麻,患儿先取平卧位,双腿屈曲分开,德国wolf” F8/9.8输尿管镜直视下置入膀胱,双侧输尿管口清晰可见,沿左侧输尿管口插入导丝,沿导丝用推管顺利置入4F输尿管导管一根,位置满意。改俯卧位,超定位下十二肋下在腋后线与肩胛下线间穿刺左肾中盏成功,引入导丝,用塑料筋膜扩张器从8F逐步扩张至16F peel-away外鞘,放入F8/9.8半硬性输尿管镜,直视下在肾盂内可见1枚约1.5cm的黄色结石,质地稍硬,肾下盏内可见散在的小结石,用钬激光光纤(600μm,1.5J×10Hz)击碎结石,利用高压循环水冲出碎石,视野内探察肾盂肾盏无明显残留结石后,顺行放置F4.7/24cm双J管,留置14F肾造瘘管一根,患儿术中生命体征平稳,手术时间90分钟,出血10ml。

【术后诊断

左肾多发结石

【术后诊疗

术后复查腹平片未见明显阳性结石,术后1个月时在全麻诱导下用输尿管镜将D-J管完整拔除,随访至今结石无复发。

【讨论内容】

文献综述:小儿尿路结石发病率不高,但多与代谢异常、尿路畸形和感染有关。国内学者报道50.6%的患儿合并尿路感染,合并尿路畸形20.0%。近来国内出现较多服用含三聚氰胺的奶粉所致的结石患儿,此例可能与此有关。

一般认为,体外震波碎石(ESWL)为治疗小儿上尿路结石的首选方法,但小儿ESWL风险较大,体位配合差,多需要全麻。Jayanthi等建议ESWL适合治疗直径≤1.5cm不复杂的小儿肾结石。对于此例复杂性结石,碎石的排出存在较多的困难。

1985年Woodside等成功应用PCNL治疗小儿肾结石以来,目前国外多应用经皮肾技术治疗小儿复杂性肾结石,但对于低龄幼儿相关报道很少。而且文献报道多采用20F~30F的Amplatz鞘作为工作通道,尽管结石清除率可达86.8%,但对小儿肾脏损伤较大。

【专家点评】

本例采用经皮微造瘘(16F),利用成人输尿管镜经此通道碎石取石,碎石效果良好。因小儿的肾脏活动度大,集合系统细小,易出血,经皮肾操作存在较大的困难与风险。我们体会应在全麻下手术,采用微造瘘通道为宜;术中操作轻柔,进入小盏时应避免过度摆动镜体,以免撕裂肾脏;尽量缩短手术时间,减低灌注压力,避免水电失衡;同时尽可能将所有残石取净,以免复发。

原始出处:

1. 那彦群, 陈 山, 王建业,等.泌尿外科疑难病例讨论精选.[M].人民卫生出版社.30-31.


2. 吴开俊,陆伟,李逊,等.小儿肾结石的ESWL和PCNL治疗.中华泌尿外科杂志,2004,25:130-132

3. Ozden E,Sahin A,Tan B,et al. Percutaneous renal surgery in children with complex stones.J Pediatr Urol,2008,4(4):295-298

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CST 2017, time=2017-08-25, status=1, ipAttribution=)]
    2017-09-11 hyf028
  2. 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    2017-08-29 laoli

    学习了.谢谢分享!

    0

  3. 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    2017-08-27 一个字-牛

    学习了谢谢分享

    0

  4. 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    2017-08-27 oliver169
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    2017-08-27 rgjl
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    2017-08-27 vera_1203
  7. 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CST 2017, time=2017-08-25, status=1, ipAttribution=)]
  8. 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encodeId=e21b23e05786, content=非常好的文章.学习了.很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Fri Aug 25 19:54:59 CST 2017, time=2017-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=237007, encodeId=f29f23e00733, content=小儿尿路结石发病率不高.但多与代谢异常.尿路畸形和感染有关., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Aug 25 15:29:39 CST 2017, time=2017-08-25, status=1, ipAttribution=)]
    2017-08-25 天涯183

    非常好的文章.学习了.很受益

    0

  9. 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encodeId=e21b23e05786, content=非常好的文章.学习了.很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Fri Aug 25 19:54:59 CST 2017, time=2017-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=237007, encodeId=f29f23e00733, content=小儿尿路结石发病率不高.但多与代谢异常.尿路畸形和感染有关., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Aug 25 15:29:39 CST 2017, time=2017-08-25, status=1, ipAttribution=)]
    2017-08-25 有备才能无患

    小儿尿路结石发病率不高.但多与代谢异常.尿路畸形和感染有关.

    0

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