孕早期感染寨卡病毒易引发小头症

2016-12-13 Margaret A. Honein 中国科学报


巴西数千婴儿因寨卡病毒感染而患小头症。图片来源: Sumaia Villela

也许与寨卡病毒感染有关的小头畸形患儿比之前报道的要多。美国《发病率与死亡率周刊》(MMWR)近日刊载的一项针对哥伦比亚寨卡疫情的新研究指出,孕妇在怀孕前三四个月感染寨卡病毒最容易引发胎儿小头症。

去年以来,寨卡病毒在巴西等美洲国家持续肆虐,而哥伦比亚是遭受这种蚊媒疾病打击最严重的国家之一,但其小头畸形病例人均比例却比其南部邻居少得多。不过,一份新报告可能得出了不同结论。美国疾病控制和预防中心(CDC)研究人员与哥伦比亚的同行展开的研究显示,今年2月至11月中旬,哥伦比亚报告476例小头症病例,是去年同期的4倍之多。

研究人员在MMWR上报告称,其中小头症病例报告最多的是今年7月,共计94例,这一数字是去年7月的约9倍,相比寨卡病例报告数量的高峰期晚来了约6个月。基于此,研究人员得出结论:“与寨卡相关的小头症最大风险期是在孕期的前半段时间,尤其是在孕早期的3个月,或孕中期(4至6个月)的早期。”

相比之下,最新的世界卫生组织(WHO)“情况报告”称,哥伦比亚只报告了60例可能与寨卡病毒有关的小头症或中枢神经系统畸形,而巴西有2211例。CDC在一份声明中说,来自哥伦比亚的最新报告证明,小头症病例数量增多并不是仅特定于巴西,所有出现寨卡疫情的国家都可能经历小头症与其他寨卡相关出生缺陷病例数量的增多。

自2015年起,全球69个国家和地区已报告出现寨卡病毒传播,其中28个国家和地区出现了与寨卡病毒相关的小头症及其他神经系统病变。不过,WHO日前宣布,寨卡病毒及其引发的神经系统病变仍是显著持续的公共卫生挑战,但已不再构成“国际关注的突发公共卫生事件”,该机构将以长期应对机制对抗这种病毒。(来源:中国科学报 张章)

原始出处

Esther Liliana Cuevas, MS, MPH1; Van T. Tong, MPH2; Nathaly Rozo1; Diana Valencia, MS2; Oscar Pacheco, MD1.Preliminary Report of Microcephaly Potentially Associated with Zika Virus Infection During Pregnancy — Colombia, January–November 2016.MMWR.2016

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1694741, encodeId=d5661694e417b, content=<a href='/topic/show?id=f80c4e003e1' target=_blank style='color:#2F92EE;'>#小头症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47003, encryptionId=f80c4e003e1, topicName=小头症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a1229733121, createdName=nian.wang1992, createdTime=Sun Apr 23 01:11:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360047, encodeId=f43a136004ead, content=<a href='/topic/show?id=6783466083f' target=_blank style='color:#2F92EE;'>#寨卡病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46608, encryptionId=6783466083f, topicName=寨卡病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394185, encodeId=fd84139418514, content=<a href='/topic/show?id=1646452e771' target=_blank style='color:#2F92EE;'>#孕早期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45277, encryptionId=1646452e771, topicName=孕早期)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/0EDD6BA8A8C6A0C23E8ABC8BA5331A25/100, createdBy=d37d2500154, createdName=ms5106640509429053, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512888, encodeId=aa9315128884d, content=<a href='/topic/show?id=f0364660360' target=_blank style='color:#2F92EE;'>#寨卡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46603, encryptionId=f0364660360, topicName=寨卡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d79610514526, createdName=12498710m14暂无昵称, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162429, encodeId=d4b31624295f, content=棒棒哒???????, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Tue Dec 13 11:29:41 CST 2016, time=2016-12-13, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1694741, encodeId=d5661694e417b, content=<a href='/topic/show?id=f80c4e003e1' target=_blank style='color:#2F92EE;'>#小头症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47003, encryptionId=f80c4e003e1, topicName=小头症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a1229733121, createdName=nian.wang1992, createdTime=Sun Apr 23 01:11:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360047, encodeId=f43a136004ead, content=<a href='/topic/show?id=6783466083f' target=_blank style='color:#2F92EE;'>#寨卡病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46608, encryptionId=6783466083f, topicName=寨卡病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394185, encodeId=fd84139418514, content=<a href='/topic/show?id=1646452e771' target=_blank style='color:#2F92EE;'>#孕早期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45277, encryptionId=1646452e771, topicName=孕早期)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/0EDD6BA8A8C6A0C23E8ABC8BA5331A25/100, createdBy=d37d2500154, createdName=ms5106640509429053, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512888, encodeId=aa9315128884d, content=<a href='/topic/show?id=f0364660360' target=_blank style='color:#2F92EE;'>#寨卡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46603, encryptionId=f0364660360, topicName=寨卡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d79610514526, createdName=12498710m14暂无昵称, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162429, encodeId=d4b31624295f, content=棒棒哒???????, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Tue Dec 13 11:29:41 CST 2016, time=2016-12-13, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1694741, encodeId=d5661694e417b, content=<a href='/topic/show?id=f80c4e003e1' target=_blank style='color:#2F92EE;'>#小头症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47003, encryptionId=f80c4e003e1, topicName=小头症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a1229733121, createdName=nian.wang1992, createdTime=Sun Apr 23 01:11:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360047, encodeId=f43a136004ead, content=<a href='/topic/show?id=6783466083f' target=_blank style='color:#2F92EE;'>#寨卡病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46608, encryptionId=6783466083f, topicName=寨卡病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394185, encodeId=fd84139418514, content=<a href='/topic/show?id=1646452e771' target=_blank style='color:#2F92EE;'>#孕早期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45277, encryptionId=1646452e771, topicName=孕早期)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/0EDD6BA8A8C6A0C23E8ABC8BA5331A25/100, createdBy=d37d2500154, createdName=ms5106640509429053, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512888, encodeId=aa9315128884d, content=<a href='/topic/show?id=f0364660360' target=_blank style='color:#2F92EE;'>#寨卡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46603, encryptionId=f0364660360, topicName=寨卡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d79610514526, createdName=12498710m14暂无昵称, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162429, encodeId=d4b31624295f, content=棒棒哒???????, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Tue Dec 13 11:29:41 CST 2016, time=2016-12-13, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1694741, encodeId=d5661694e417b, content=<a href='/topic/show?id=f80c4e003e1' target=_blank style='color:#2F92EE;'>#小头症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47003, encryptionId=f80c4e003e1, topicName=小头症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a1229733121, createdName=nian.wang1992, createdTime=Sun Apr 23 01:11:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360047, encodeId=f43a136004ead, content=<a href='/topic/show?id=6783466083f' target=_blank style='color:#2F92EE;'>#寨卡病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46608, encryptionId=6783466083f, topicName=寨卡病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394185, encodeId=fd84139418514, content=<a href='/topic/show?id=1646452e771' target=_blank style='color:#2F92EE;'>#孕早期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45277, encryptionId=1646452e771, topicName=孕早期)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/0EDD6BA8A8C6A0C23E8ABC8BA5331A25/100, createdBy=d37d2500154, createdName=ms5106640509429053, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512888, encodeId=aa9315128884d, content=<a href='/topic/show?id=f0364660360' target=_blank style='color:#2F92EE;'>#寨卡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46603, encryptionId=f0364660360, topicName=寨卡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d79610514526, createdName=12498710m14暂无昵称, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162429, encodeId=d4b31624295f, content=棒棒哒???????, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Tue Dec 13 11:29:41 CST 2016, time=2016-12-13, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1694741, encodeId=d5661694e417b, content=<a href='/topic/show?id=f80c4e003e1' target=_blank style='color:#2F92EE;'>#小头症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47003, encryptionId=f80c4e003e1, topicName=小头症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a1229733121, createdName=nian.wang1992, createdTime=Sun Apr 23 01:11:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360047, encodeId=f43a136004ead, content=<a href='/topic/show?id=6783466083f' target=_blank style='color:#2F92EE;'>#寨卡病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46608, encryptionId=6783466083f, topicName=寨卡病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394185, encodeId=fd84139418514, content=<a href='/topic/show?id=1646452e771' target=_blank style='color:#2F92EE;'>#孕早期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45277, encryptionId=1646452e771, topicName=孕早期)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/0EDD6BA8A8C6A0C23E8ABC8BA5331A25/100, createdBy=d37d2500154, createdName=ms5106640509429053, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512888, encodeId=aa9315128884d, content=<a href='/topic/show?id=f0364660360' target=_blank style='color:#2F92EE;'>#寨卡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46603, encryptionId=f0364660360, topicName=寨卡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d79610514526, createdName=12498710m14暂无昵称, createdTime=Thu Dec 15 02:11:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162429, encodeId=d4b31624295f, content=棒棒哒???????, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Tue Dec 13 11:29:41 CST 2016, time=2016-12-13, status=1, ipAttribution=)]
    2016-12-13 1e184d7bm65(暂无匿称)

    棒棒哒???????

    0

相关资讯

世卫专家:寨卡疫苗进入临床试验阶段

世界卫生组织专家26日在通报6月至9月世卫“寨卡战略应对方案”执行情况时指出,当前全球寨卡疫情应对仍然不容乐观,不过来自美国与韩国的两种寨卡疫苗已进入第一阶段临床试验。 世卫组织寨卡病毒事件管理执行经理鲍里斯·保林当天在日内瓦万国宫举行的发布会上介绍说,全球至少30家机构及公司正在研发寨卡疫苗,分别由美国国家过敏症和传染病研究所和韩国“基因一号”生命科学公司研制的两种DNA(脱氧核糖核酸)

Nature:惊人发现,寨卡会影响男性生育力?

导语:众所周知,寨卡病毒会导致新生儿小头畸形和一种严重的神经疾病。目前人们主要在研究寨卡病毒影响孕妇和胎儿的具体机制。然而Nature杂志发表的一项最新研究表明,寨卡病毒感染可能对男性也有很大危害,会严重干扰其生育能力。众所周知,寨卡病毒会导致新生儿小头畸形和一种严重的神经疾病。目前人们主要在研究寨卡病毒影响孕妇和胎儿的具体机制。然而Nature杂志发表的一项最新研究表明,寨卡病毒感染可能对男性也

Cell:高福院士、李向东教授发现Zika病毒或导致雄性小鼠不育!

导语:近期,中国科学院微生物研究所研究员、中科院院士高福团队和中国农业大学教授李向东课题组合作揭示Zika病毒(ZIKV)会损害雄性小鼠睾丸组织,导致不育问题。这一研究从新的角度揭示了Zika病毒对生殖健康的影响,或将引起新的关注。相关研究成果在线发表在Cell期刊。近期,中国科学院微生物研究所研究员、中科院院士高福团队和中国农业大学教授李向东课题组合作在《Cell》期刊在线发表一篇题为“Zika

美国开始寨卡灭活疫苗临床试验

继今年8月启动一项寨卡疫苗临床试验后,美国科学家于11月7日又宣布启动另一种寨卡疫苗的一期临床试验。 美国国家过敏症和传染病研究所所长安东尼·福奇在一份声明中说,寨卡病毒仍在继续扩散,对孕妇及其婴儿尤其不利。“我们迫切需要一种安全、有效的寨卡疫苗,保护人们不被寨卡病毒感染。” 受美国国家过敏症和传染病研究所资助,美国沃尔特·里德陆军研究所当天开始测试一种纯化灭活寨卡疫苗的安全性以及