ASCO 2016的Panel Discussion,看大牛如何提问?!

2016-06-10 MedSci MedSci原创

ASCO 的Panel Discussion,那些让人目瞪口呆的问题 2016年的ASCO ,华丽谢幕,国内的看官们已经被铺天盖地的图文包围了。偶然听到Lung Cancer-Non-Small Cell Metastatic Oral session 的一段panel discussion,一群犀利哥的问题,忍不住想跟大家分享一下。 ▼ 先是一个日本presenter ,Hiros

ASCO 的Panel Discussion,那些让人目瞪口呆的问题

2016年的ASCO ,华丽谢幕,国内的看官们已经被铺天盖地的图文包围了。偶然听到Lung Cancer-Non-Small Cell Metastatic Oral session 的一段panel discussion,一群犀利哥的问题,忍不住想跟大家分享一下。


先是一个日本presenter ,Hiroshi Nokihara 呈现了J ALEX的数据,结果大家都知道,Alec组vs crizotinib HR 为0.34, Alec 一线PFS可能超过20.3m(该数据有50%的成熟度);



然后是韩国的presenter ,Dong-wan Kim ,呈现了 brigatinib(AP26113)在ALK阳性二线治疗的数据,PFS 12.4m,也很漂亮
 

再然后,这位印度大叔 Shirish M.Gadgeel雄赳赳的抛出了一个议题:ALK positive NSCLC, which drug to choose first。

然后,热闹的panel discussion就开始了印度大叔遭遇了第一个问题

Q1:How many inhibitors do we need ?Do we need ceritinib?一股凌厉的气息扑面而来,刚一问完,会场响起了心领神会的笑声。。。

Q2:肿瘤届男神Tony Mok问了第二个杀气腾腾的问题,在J-ALEX中,脑转移人群Alec对比cirzotinib的HR达到了0.08,这是一个好到令人难以置信的数字,意味着,Alec降低92%的颅内进展风险,这是什么原因?是否与中期终止较短的随访有关?脑转移人群的具体特征包括什么,颅内病灶的大小和数量如何分布?
脑转移的数字,见下图(估计好多人都很难看见。。。。。。Tony,乃是火眼晶晶吗?)脑转移这部分的数据确实引人注意,同期ASCO -poster的PROFILE 1029 中,一线cirzotinib组入组20%脑转移人群,而化疗组入组了31%脑转移人群,这种两组间的不均衡也值得探讨

Q3 :Do we have more infromation about Alec resistant profile? Are you going to carry out rebiopsy after disease progression on Alec arm?(来自中国的一位参会者)


Q4:ALK 之父,Alectinib北美PhaseII 临床的第一作者 Sai hong Ou,一连问了3-4个问题,J Alex中,crizotinib组进展后是否cross到Alectinib组?你们会观测PFS2吗?

Q5:在日本,色瑞替尼,仅被批准作为crizotinib失败后的二线用药,Alectinib组进展后的方案是什么?

Q6:现在我们看到了ALTA(最长的二线数据),看到了J ALEX(最长的一线数据),这些数据都非常的漂亮,难道一线的较量,不应该是Alectinib对比brigatinib吗?

看的出来,日本的presenter已经很努力在回答这些同样是亚洲面孔的thoughts leader的问题,但画面总感觉像奥特曼们群殴小怪兽。。。。。。能说一口流利的英语,在这个时候是多么的重要啊

问题是,reader们,你们有答案吗?

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    2016-10-20 vividelife
  3. 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    2017-03-24 nymo
  4. 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encryptionId=220059936c, topicName=Discussion)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Mon Feb 27 15:36:00 CST 2017, time=2017-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938589, encodeId=3d75193858956, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Aug 25 14:36:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89672, encodeId=78d7896e2c8, content=有视频么 想看, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2012097, encodeId=5d96201209e8e, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Mar 14 19:36:00 CST 2017, time=2017-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786081, encodeId=7d6a1e8608101, content=<a href='/topic/show?id=e27d13e1792' target=_blank style='color:#2F92EE;'>#panel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13717, encryptionId=e27d13e1792, topicName=panel)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, createdName=vividelife, createdTime=Thu Oct 20 04:36:00 CST 2016, time=2016-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1649417, encodeId=015f164941efb, content=<a href='/topic/show?id=081a16e10e8' target=_blank style='color:#2F92EE;'>#SSI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16710, encryptionId=081a16e10e8, topicName=SSI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=586523824746, createdName=nymo, createdTime=Fri Mar 24 07:36:00 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784356, encodeId=b0951e843569c, content=<a href='/topic/show?id=220059936c' target=_blank style='color:#2F92EE;'>#Discussion#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5993, encryptionId=220059936c, topicName=Discussion)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Mon Feb 27 15:36:00 CST 2017, time=2017-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938589, encodeId=3d75193858956, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Aug 25 14:36:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89672, encodeId=78d7896e2c8, content=有视频么 想看, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
    2016-08-25 quxin068
  6. [GetPortalCommentsPageByObjectIdResponse(id=2012097, encodeId=5d96201209e8e, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Mar 14 19:36:00 CST 2017, time=2017-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786081, encodeId=7d6a1e8608101, content=<a href='/topic/show?id=e27d13e1792' target=_blank style='color:#2F92EE;'>#panel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13717, encryptionId=e27d13e1792, topicName=panel)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
    2016-06-12 马里奥8433

    有视频么 想看

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2012097, encodeId=5d96201209e8e, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Mar 14 19:36:00 CST 2017, time=2017-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786081, encodeId=7d6a1e8608101, content=<a href='/topic/show?id=e27d13e1792' target=_blank style='color:#2F92EE;'>#panel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13717, encryptionId=e27d13e1792, topicName=panel)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, createdName=vividelife, createdTime=Thu Oct 20 04:36:00 CST 2016, time=2016-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1649417, encodeId=015f164941efb, content=<a href='/topic/show?id=081a16e10e8' target=_blank style='color:#2F92EE;'>#SSI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16710, encryptionId=081a16e10e8, topicName=SSI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=586523824746, createdName=nymo, createdTime=Fri Mar 24 07:36:00 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784356, encodeId=b0951e843569c, content=<a href='/topic/show?id=220059936c' target=_blank style='color:#2F92EE;'>#Discussion#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5993, encryptionId=220059936c, topicName=Discussion)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Mon Feb 27 15:36:00 CST 2017, time=2017-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938589, encodeId=3d75193858956, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Aug 25 14:36:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89672, encodeId=78d7896e2c8, content=有视频么 想看, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
    2016-06-12 yankaienglish
  8. 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encryptionId=220059936c, topicName=Discussion)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Mon Feb 27 15:36:00 CST 2017, time=2017-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938589, encodeId=3d75193858956, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Aug 25 14:36:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89672, encodeId=78d7896e2c8, content=有视频么 想看, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
    2016-06-10 milkshark

    的确不错

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2012097, encodeId=5d96201209e8e, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Mar 14 19:36:00 CST 2017, time=2017-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786081, encodeId=7d6a1e8608101, content=<a href='/topic/show?id=e27d13e1792' target=_blank style='color:#2F92EE;'>#panel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13717, encryptionId=e27d13e1792, topicName=panel)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, createdName=vividelife, createdTime=Thu Oct 20 04:36:00 CST 2016, time=2016-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1649417, encodeId=015f164941efb, content=<a href='/topic/show?id=081a16e10e8' target=_blank style='color:#2F92EE;'>#SSI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16710, encryptionId=081a16e10e8, topicName=SSI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=586523824746, createdName=nymo, createdTime=Fri Mar 24 07:36:00 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784356, encodeId=b0951e843569c, content=<a href='/topic/show?id=220059936c' target=_blank style='color:#2F92EE;'>#Discussion#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5993, encryptionId=220059936c, topicName=Discussion)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Mon Feb 27 15:36:00 CST 2017, time=2017-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938589, encodeId=3d75193858956, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Aug 25 14:36:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89672, encodeId=78d7896e2c8, content=有视频么 想看, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
    2016-06-10 milkshark

    值得学习

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=2012097, encodeId=5d96201209e8e, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Mar 14 19:36:00 CST 2017, time=2017-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786081, encodeId=7d6a1e8608101, content=<a href='/topic/show?id=e27d13e1792' target=_blank style='color:#2F92EE;'>#panel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13717, encryptionId=e27d13e1792, topicName=panel)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eocJY6moGTnYzC8V8lUl3k679Uxh0PVMjIamhoDYuSYr6D4KDKlbpuNuCKFlJaiaVrmFIrbseIWqUA/132, createdBy=ad571630249, createdName=马里奥8433, createdTime=Sun Jun 12 20:05:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587796, encodeId=1f42158e796e4, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Sun Jun 12 01:36:00 CST 2016, time=2016-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89224, encodeId=e77b8922421, content=的确不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89225, encodeId=83b68922584, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Fri Jun 10 19:38:00 CST 2016, time=2016-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89207, encodeId=350c8920e34, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=d0921674448, createdName=gyczyxy, createdTime=Fri Jun 10 13:33:00 CST 2016, time=2016-06-10, status=1, ipAttribution=)]
    2016-06-10 gyczyxy

    了解

    0

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