PLoS One:踝臂血压指数小于0.9是发生卒中的独立危险因素?

2015-10-27 phylis 译 MedSci原创

目的:研究者调查了有卒中史的中国成人中踝臂血压指数(ABI),双臂血压(BP)的差及踝间血压差的相关性。方法:这个研究选取中国高血压研究调查中的1485名受试者,年龄大于35岁。研究者应用示波设备检测四肢血压,并计算ABI及臂间血压差/踝间血压差。应用logistic回归分析评估血压参数和卒中史的其他因素的相关性。结果:在单变量分析中,受试者ABI <0.9,臂间血压差≥15 mmHg及踝间

目的:研究者调查了有卒中史的中国成人中踝臂血压指数(ABI),双臂血压(BP)的差、踝间血压差与卒中的相关性。

方法:这个研究选取中国高血压研究调查中的1485名受试者,年龄大于35岁。研究者应用示波设备检测四肢血压,并计算ABI及臂间血压差/踝间血压差。应用logistic回归分析评估血压参数和卒中史的其他因素的相关性。

结果:在单变量分析中,受试者ABI <0.9,臂间血压差≥15 mmHg及踝间血压差≥10 mmHg与卒中发生较高相关。多元logistic回归分析表示,校正臂间血压差≥15 mmHg及踝间血压差≥10 mmHg和传统的卒中危险因素,ABI<0.9与卒中史独立相关。当高血压和ABI两个变量移出回归模型时,发现踝间血压差≥10 mmHg与先前卒中相关。净重新分类的改进分析显示将踝间血压差≥10 mmHg作为独立的危险因素(年龄、卒中家族史、高血压和ABI),使得净分类增加11.92%。

结论:ABI <0.9是中国成年人发生卒中的独立危险因素,但是,这只是检测了小部分的受试者。将踝间血压差≥10 mmHg作为卒中的独立的危险因子能改善对卒中的预测能力。

原文出处:

Guo H, Sun F, Dong L,et al. The Association of Four-Limb Blood Pressure with History of Stroke in Chinese Adults: A Cross-Sectional Study. PLoS One. 2015,Oct 9


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