世界首例深低温冷冻自体皮肤治疗在辽宁获得成功

2017-10-19 朱明宇 中国新闻网

本次盛京医院自行深低温冷冻自体皮治疗大面积皮肤撕脱伤,尚属世界首例。

中国医科大学附属盛京医院18日发布消息称,世界首例深低温冷冻自体皮肤治疗大面积撕脱获得成功。

据盛京医院手足踝显微外科病房主任田立杰教授18日介绍,一位女性患者在1个多月前因车祸碾压造成左下腹及大腿损伤,导致皮肤大面积撕脱。

医疗机构以往面对此类患者,一般会采取取皮植皮或原位缝合。取皮回植成活率约60%,并可能危及患者生命;原位缝合会在数日后因皮瓣缺血导致此处皮肤大部分坏死,造成皮肤浪费。

在国际上,有医生曾采取最低至-80℃的冰箱保存皮肤用于植皮,但保存液或设备昂贵,且保存时间短,过程复杂。

田立杰表示,在-196℃液氮中保存皮肤已应用了几十年,技术成熟,但此前都是应用在异体皮上,理论上可以通过完善技术尝试自体皮肤保存。他为此带领科研小组查找了大量文献,准备了相关器械和药品,创造性地将患者自体皮肤保存在液氮中,以最大限度保证细胞活性。

经医生密切关注患者的身体情况,待其创面经皮肤保护材料覆盖及全身营养状态调整好后,立即取出保存的皮肤原位植皮以闭合创面,最终获得了95%的植皮成活率。

由于深低温冷冻可以降低组织代谢,减少营养物质及氧的需求,使撕脱的皮肤保存期可达一年甚至更久,患者因此可避免复杂的皮瓣移植手术。

据公开资料显示,仅2012年一名意大利医生Mario Dini在其国家皮库的协助下保存了患者皮肤,再二期植皮获得成功。而本次盛京医院自行深低温冷冻自体皮治疗大面积皮肤撕脱伤,尚属世界首例,这也标志着中国此项医疗技术达到国际领先水平。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1968458, encodeId=cbd419684586d, content=<a href='/topic/show?id=a57f208660f' target=_blank style='color:#2F92EE;'>#世界首例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20866, encryptionId=a57f208660f, topicName=世界首例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Fri Jul 06 01:44:00 CST 2018, time=2018-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254298, encodeId=3ecd2542988b, content=厉害了, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/16/e9fe76b8a03f249298f44ed7d5e78b3d.jpg, createdBy=1d9b2002194, createdName=痛快淋漓, createdTime=Thu Oct 19 11:53:54 CST 2017, time=2017-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254280, encodeId=e10f2542809b, content=非常厉害.期待能看到相关联的视频, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/b594a756d77e4171b5313e531ef89b43/31c000a8a97d4872b698c80fb8a33369.jpg, createdBy=624b2152505, createdName=大叔默默路过, createdTime=Thu Oct 19 11:18:40 CST 2017, time=2017-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254271, encodeId=76512542e1f3, content=超厉害的说, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Oct 19 10:17:36 CST 2017, time=2017-10-19, status=1, ipAttribution=)]
    2017-10-19 痛快淋漓

    厉害了

    0

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    2017-10-19 大叔默默路过

    非常厉害.期待能看到相关联的视频

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1968458, encodeId=cbd419684586d, content=<a href='/topic/show?id=a57f208660f' target=_blank style='color:#2F92EE;'>#世界首例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20866, encryptionId=a57f208660f, topicName=世界首例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Fri Jul 06 01:44:00 CST 2018, time=2018-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254298, encodeId=3ecd2542988b, content=厉害了, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/16/e9fe76b8a03f249298f44ed7d5e78b3d.jpg, createdBy=1d9b2002194, createdName=痛快淋漓, createdTime=Thu Oct 19 11:53:54 CST 2017, time=2017-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254280, encodeId=e10f2542809b, content=非常厉害.期待能看到相关联的视频, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/b594a756d77e4171b5313e531ef89b43/31c000a8a97d4872b698c80fb8a33369.jpg, createdBy=624b2152505, createdName=大叔默默路过, createdTime=Thu Oct 19 11:18:40 CST 2017, time=2017-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254271, encodeId=76512542e1f3, content=超厉害的说, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Oct 19 10:17:36 CST 2017, time=2017-10-19, status=1, ipAttribution=)]
    2017-10-19 戒馋,懒,贪

    超厉害的说

    0